Blar i Bergen Open Research Archive på forfatter "Malinen, Eirik"
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Combined RBE and OER optimization in proton therapy with FLUKA based on EF5-PET
Henjum, Helge; Dahle, Tordis Johnsen; Mairani, Andrea; Pilskog, Sara Margareta Cecilia; Stokkevåg, Camilla Hanquist; Boer, Camilla Grindeland; Redalen, Kathrine Røe; Minn, Heikki; Malinen, Eirik; Ytre-Hauge, Kristian Smeland (Journal article; Peer reviewed, 2023)Introduction Tumor hypoxia is associated with poor treatment outcome. Hypoxic regions are more radioresistant than well-oxygenated regions, as quantified by the oxygen enhancement ratio (OER). In optimization of proton ... -
The FLUKA Monte Carlo code coupled with an OER model for biologically weighted dose calculations in proton therapy of hypoxic tumors
Dahle, Tordis Johnsen; Rusten, Espen; Stokkevåg, Camilla Hanquist; Silvoniemi, Antti; Mairani, Andrea; Fjæra, Lars Fredrik; Rørvik, Eivind; Henjum, Helge; Wright, Pauliina; Boer, Camilla Grindeland; Forsback, Sarita; Minn, Heikki; Malinen, Eirik; Ytre-Hauge, Kristian (Journal article; Peer reviewed, 2020)Introduction The increased radioresistance of hypoxic cells compared to well-oxygenated cells is quantified by the oxygen enhancement ratio (OER). In this study we created a FLUKA Monte Carlo based tool for inclusion of ... -
Microdosimetry with a 3D silicon on insulator (SOI) detector in a low energy proton beamline
Samnøy, Andreas Tefre; Ytre-Hauge, Kristian; Malinen, Eirik; Tran, Linh; Rosenfeld, Anatoly; Povoli, Marco; Kok, Angela Chun Ying; Summanwar, Anand; Røhrich, Dieter (Journal article; Peer reviewed, 2020)An accurate description of the radiation quality of proton beams is a precondition to increase our understanding of radiobiological mechanisms and to develop accurate biological response models for radiotherapy. However, ... -
Volumetric parameters from [18F]FDG PET/CT predicts survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms
Langen Stokmo, Henning; Aly, Mahmoud; Lothe, Inger Marie Bowitz; Borja, Austin J.; Seraj, Siavash Mehdizadeh; Ghorpade, Rina; Miao, Xuan; Hjortland, Geir Olav; Malinen, Eirik; Sorbye, Halfdan; Werner, Thomas J.; Alavi, Abass; Rootwelt-Revheim, Mona Elisabeth (Journal article; Peer reviewed, 2022)A positive fluorine-18 labelled 2-deoxy-2-fluoroglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) has been associated with more aggressive disease and less differentiated neuroendocrine neoplasms ...