• Blood glucose and risk of incident and fatal cancer in the metabolic syndrome and cancer project (me-can): analysis of six prospective cohorts 

      Stocks, Tanja; Rapp, Kilian; Bjørge, Tone; Manjer, Jonas; Ulmer, Hanno; Selmer, Randi Marie; Lukanova, Annekatrin; Johansen, Dorthe; Concin, Hans; Tretli, Steinar; Hallmans, Göran; Jonsson, Håkan; Stattin, Pär (Peer reviewed; Journal article, 2009-12-22)
      Background: Prospective studies have indicated that elevated blood glucose levels may be linked with increased cancer risk, but the strength of the association is unclear. We examined the association between blood glucose ...
    • Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development 

      Li, Yafang; Xiao, Xiangjun; Bossé, Yohan; Gorlova, Olga; Gorlov, Ivan; Han, Younghun; Byun, Jinyoung; Leighl, Natasha; Johansen, Jakob S.; Barnett, Matt; Chen, Chu; Goodman, Gary; Cox, Angela; Taylor, Fiona; Woll, Penella; Wichmann, Erich; Manz, Judith; Muley, Thomas; Risch, Angela; Rosenberger, Albert; Han, Jiali; Siminovitch, Katherine; Arnold, Susanne; Haura, Eric B.; Bolca, Ciprian; Holcátová, Ivana; Janout, Vladimir; Kontic, Milica; Lissowska, Jolanta; Mukeria, Anush; Ognjanovic, Simona; Orlowski, Tadeusz M.; Scelo, Ghislaine; Swiatkowska, Beata; Zaridze, David; Bakke, Per S.; Skaug, Vidar; Zienolddiny, Shanbeh; Duell, Eric J.; Butler, Lesley M.; Houlston, Richard; Artigas, Maria Soler; Grankvist, Kjell; Johansson, Mikael; Shepherd, Frances A.; Marcus, Michael; Brunnström, Hans; Manjer, Jonas; Melander, Olle; Muller, David C.; Overvad, Kim; Trichopoulou, Antonia; Tumino, Rosaria; Liu, Geoffrey; Bojesen, Stig; Wu, Xifeng; Le Marchand, Loic; Albanes, Demetrios; Bickeböller, Heike; Aldrich, Melinda C.; Bush, William S.; Tardon, Adonina; Rennert, Gad; Teare, M. Dawn; Field, John K.; Kiemeney, Lambertus A.; Lazarus, Philip; Haugen, Aage; Lam, Stephen; Schabath, Matthew B.; Andrew, Angeline S.; Bertazzi, Pier Alberto; Pesatori, Angela C.; Christiani, David C.; Caporaso, Neil; Johansson, Mattias; McKay, James D.; Brennan, Paul; Hung, Rayjean J.; Amos, Christopher I. (Peer reviewed; Journal article, 2019)
      The development of cancer is driven by the accumulation of many oncogenesis-related genetic alterationsand tumorigenesis is triggered by complex networks of involved genes rather than independent actions. To explore the ...
    • Identification of susceptibility pathways for the roleof chromosome 15q25.1 in modifying lung cancerrisk 

      Ji, Xuemei; Bossé, Yohan; Landi, Maria Teresa; Gui, Jiang; Xiao, Xiangjun; Qian, David C; Joubert, Philippe; Lamontagne, Maxime; Li, Yafang; Gorlov, Ivan; de Biasi, Mariella; Han, Younghun; Gorlova, Olga; Hung, Rayjean J.; Wu, Xifeng; McKay, James; Zong, Xuchen; Carreras-Torres, Robert; Christiani, David C.; Caporaso, Neil; Johansson, Mattias; Liu, Geoffrey; Bojesen, Stig E.; Le Marchand, Loic; Albanes, Demetrios; Bickeboller, Heike; Aldrich, Melinda C.; Bush, William S.; Tardon, Adonina; Rennert, Gad; Chen, Chu; Teare, M. Dawn; Field, John K.; Kiemeney, Lambertus A.; Lazarus, Philip; Haugen, Aage; Lam, Stephen; Schabath, Matthew B.; Andrew, Angeline S.; Shen, Hongbing; Hong, Yun-Chul; Yuan, Jian-Min; Bertazzi, Pier A.; Pesatori, Angela C.; Ye, Yuanqing; Diao, Nancy; Su, Li; Zhang, Ruyang; Brhane, Yonathan; Leighl, Natasha; Johansen, Jakob S.; Mellemgaard, Anders; Saliba, Walid; Haiman, Christopher; Wilkens, Lynne; Fernandez-Somoano, Ana; Fernandez-Tardon, Guillermo; van der Heijden, Erik H. F. M.; Kim, Jin Hee; Dai, Juncheng; Hu, Zhibin; Davies, Michael P.A.; Marcus, Michael W.; Brunnström, Hans; Manjer, Jonas; Melander, Olle; Muller, David C.; Overvad, Kim; Trichopoulou, Antonia; Tumino, Rosario; Doherty, Jennifer; Goodman, Gary; Cox, Angela; Taylor, Fiona; Woll, Penella; Brüske, Irene; Manz, Judith; Muley, Thomas; Risch, Angela; Rosenberger, Albert; Grankvist, Kjell; Johansson, Mikael; Shepherd, Frances; Ming-Sound, Tsao; Arnold, Susanne M.; Haura, Eric B.; Bolca, Ciprian; Holcatova, Ivana; Janout, Vladimir; Kontic, Milica; Lissowska, Jolanta; Mukeria, Anush; Ognjanovic, Simona; Orlowski, Tadeusz M.; Scelo, Ghislaine; Swiatkowska, Beata; Zaridze, David; Bakke, Per S.; Skaug, Vidar; Zienolddiny, Shanbeh; Duell, Eric J.; Butler, Lesley M.; Koh, Woon-Puay; Gao, Yu-Tang; Houlston, Richard; McLaughlin, John; Stevens, Victoria; Nickle, David C.; Obeidat, Ma'en; Timens, Wim; Zhu, Bin; Song, Lei; Artigas, María Soler; Tobin, Martin D.; Wain, Louise V.; Gu, Fangyi; Byun, Jinyoung; Kamal, Ahsan; Zhu, Dakai; Tyndale, Rachel F.; Wei, Wei-Qi; Chanock, Stephen; Brennan, Paul; Amos, Christopher I. (Peer reviewed; Journal article, 2018-08-13)
      Genome-wide association studies (GWAS) identified the chromosome 15q25.1 locus as a leading susceptibility region for lung cancer. However, the pathogenic pathways, through which susceptibility SNPs within chromosome 15q25.1 ...
    • Linear age-course effects on the associations between body mass index, triglycerides, and female breast and male liver cancer risk: An internal replication study of 800,000 individuals 

      Häggström, Christel; Jonsson, Håkan; Bjørge, Tone; Nagel, Gabriele; Manjer, Jonas; Ulmer, Hanno; Drake, Isabel; Ghaderi, Sara; Lang, Alois; Engeland, Anders; Stattin, Pär; Stocks, Tanja (Peer reviewed; Journal article, 2019)
      Apart from the consistently observed differential association between obesity and breast cancer risk by menopausal status, the associations between obesity and other metabolic imbalances with risks of cancers have not been ...
    • Metabolic risk factors for esophageal squamous cell carcinoma and adenocarcinoma: a prospective study of 580 000 subjects within the Me-Can project 

      Lindkvist, Björn; Johansen, Dorthe; Stocks, Tanja; Concin, Hans; Bjørge, Tone; Almquist, Martin; Häggström, Christel; Engeland, Anders; Hallmans, Göran; Nagel, Gabriele; Jonsson, Håkan; Selmer, Randi; Ulmer, Hanno; Tretli, Steinar; Stattin, Pär; Manjer, Jonas (Peer reviewed; Journal article, 2014-02-18)
      Background: Obesity is associated with an increased risk of esophageal adenocarcinoma (EAC) and a decreased risk of esophageal squamous cell carcinoma (ESCC). However, little is known about the risk of EAC and ESCC related ...
    • Metabolic risk score and cancer risk: pooled analysis of seven cohorts 

      Stocks, Tanja; Bjørge, Tone; Ulmer, Hanno; Manjer, Jonas; Häggström, Christel; Nagel, Gabriele; Engeland, Anders; Johansen, Dorthe; Hallmans, Göran; Selmer, Randi; Concin, Hans; Tretli, Steinar; Jonsson, Håkan; Stattin, Pär (Peer reviewed; Journal article, 2015)
      Background: There are few data on the joint influence of metabolic factors on risk of separate cancers. Methods: We analysed data on body mass index, blood pressure and plasma levels of glucose, total cholesterol and ...
    • Pooled cohort study on height and risk of cancer and cancer death 

      Wiren, Sara; Häggström, Christel; Ulmer, Hanno; Manjer, Jonas; Bjørge, Tone; Nagel, Gabriele; Johansen, Dorthe; Hallmans, Göran; Engeland, Anders; Concin, Hans; Jonsson, Håkan; Selmer, Randi; Tretli, Steinar; Stocks, Tanja; Stattin, Pär (Peer reviewed; Journal article, 2013-10-31)
      Purpose: To assess the association between height and risk of cancer and cancer death. Methods: The metabolic syndrome and cancer project is a prospective pooled cohort study of 585,928 participants from seven cohorts in ...
    • A prospective study on metabolic risk factors and gallbladder cancer in the metabolic syndrome and cancer (Me-Can) collaborative study 

      Borena, Wegene; Edlinger, Michael; Bjørge, Tone; Häggström, Christel; Lindkvist, Björn; Nagel, Gabriele; Engeland, Anders; Stocks, Tanja; Strohmaier, Susanne; Manjer, Jonas; Selmer, Randi; Tretli, Steinar; Concin, Hans; Hallmans, Göran; Jönsson, Håkan; Stattin, Pär; Ulmer, Hanno (Peer reviewed; Journal article, 2014-02-21)
      Objective: To investigate the association between metabolic risk factors (individually and in combination) and risk of gallbladder cancer (GBC). Methods: The metabolic syndrome and cancer project (Me-Can) includes cohorts ...
    • The triglyceride-glucose index as a measure of insulin resistance and risk of obesity-related cancers 

      Fritz, Josef; Bjørge, Tone; Nagel, Gabriele; Manjer, Jonas; Engeland, Anders; Häggström, Christel; Concin, Hans; Teleka, Stanley; Tretli, Steinar; Gylling, Björn; Lang, Alois; Stattin, Pär; Stocks, Tanja; Ulmer, Hanno (Peer reviewed; Journal article, 2020)
      Background: The role of insulin resistance as a mediator in the association of body mass index (BMI) with site-specific cancer risk has, to our knowledge, never been systematically quantified. Methods: Altogether 510 471 ...