Browsing Bergen Open Research Archive by Author "Manyahi, Joel"
Now showing items 1-13 of 13
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Antibiotic use at a tertiary hospital in Tanzania: findings from a point prevalence survey
Katyali, Denis; Kawau, Godfrey; Blomberg, Bjørn; Manyahi, Joel (Journal article; Peer reviewed, 2023)Background In Tanzania, data on antibiotic use at the patient level is scarce, and intervention measures to optimize antibiotic use and reduce antimicrobial resistance are rarely performed. Objectives To describe ... -
Bacteraemia, Malaria, and Case Fatality Among Children Hospitalized With Fever in Dar es Salaam, Tanzania
Moyo, Sabrina John; Manyahi, Joel; Blomberg, Bjørn; Tellevik, Marit Gjerde; Masoud, Nahya Salim; Aboud, Said; Manji, Karim; Roberts, Adam P.; Hanevik, Kurt; Mørch, Kristine; Langeland, Nina (Journal article; Peer reviewed, 2020)Background: Febrile illness is the commonest cause of hospitalization in children <5 years in sub-Saharan Africa, and bacterial bloodstream infections and malaria are major causes of death. Methods: From March 2017 to ... -
First identification of bla NDM-5 producing Escherichia coli from neonates and a HIV infected adult in Tanzania
Manyahi, Joel; Moyo, Sabrina John; Kibwana, Upendo; Goodman, Richard N.; Allman, Ellie; Hubbard, Alasdair T.M.; Blomberg, Bjørn; Langeland, Nina; Roberts, Adam P. (Journal article; Peer reviewed, 2022)Introduction. Carbapenem-resistant members of the family Enterobacteriaceae are emerging as a global public-health threat and cause substantial challenges in clinical practice. Gap Statement. There is a need for increased ... -
Fluoroquinolone resistance among fecal extended spectrum βeta lactamases positive Enterobacterales isolates from children in Dar es Salaam, Tanzania
Kibwana, Upendo O.; Manyahi, Joel; Sandnes, Helene Heitmann; Blomberg, Bjørn; Mshana, Stephen E.; Langeland, Nina; Roberts, Adam P.; Moyo, Sabrina John (Journal article; Peer reviewed, 2023-03-07)Background: Fluoroquinolones have been, and continue to be, routinely used for treatment of many bacterial infections. In recent years, most parts of the world have reported an increasing trend of fluoroquinolone resistant ... -
Gastrointestinal colonization of extended-spectrum beta-lactamase-producing bacteria among children below five years of age hospitalized with fever in Dar es Salaam, Tanzania
Kibwana, Upendo O.; Manyahi, Joel; Sandnes, Helene Heitmann; Blomberg, Bjørn; Mshana, Stephen E.; Langeland, Nina; Moyo, Sabrina John (Journal article; Peer reviewed, 2022)Objectives: Gastrointestinal colonization of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) is of concern because prior colonization increases risk for subsequent infections. To date, the link between ... -
Genetic determinants of macrolide and tetracycline resistance in penicillin non-susceptible Streptococcus pneumoniae isolates from people living with HIV in Dar es Salaam, Tanzania
Manyahi, Joel; Moyo, Sabrina John; Langeland, Nina; Blomberg, Bjørn (Journal article; Peer reviewed, 2023-02-20)Background: Over one million yearly deaths are attributable to Streptococcus pneumoniae and people living with HIV are particularly vulnerable. Emerging penicillin non-susceptible Streptococcus pneumoniae (PNSP) challenges ... -
High prevalence of fecal carriage of extended spectrum β-lactamase-producing enterobacteriaceae among newly HIV-diagnosed adults in a community setting in Tanzania
Manyahi, Joel; Moyo, Sabrina John; Tellevik, Marit Gjerde; Langeland, Nina; Blomberg, Bjørn (Journal article; Peer reviewed, 2020)Colonization in HIV-infected populations with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) is particularly worrisome in low-income settings. This study describes the prevalence of ESBL-PE carriage ... -
High rate of antimicrobial resistance and multiple mutations in the dihydrofolate reductase gene among Streptococcus pneumoniae isolated from HIV-infected adults in a community setting in Tanzania
Manyahi, Joel; Moyo, Sabrina John; Aboud, Said; Langeland, Nina; Blomberg, Bjørn (Journal article; Peer reviewed, 2020)Objectives: The aim of this study was to characterize molecular mechanisms of resistance to trimethoprim and other antibiotics in Streptococcus pneumoniae isolates from HIV-infected adults in Dar es Salaam, Tanzania. Methods: ... -
Molecular characterisation of the first New Delhi metallo-β-lactamase 1-producing Acinetobacter baumannii from Tanzania
Moyo, Sabrina John; Manyahi, Joel; Hubbard, Alasdair T. M; Byrne, Rachel L; Masoud, Nahya Salim; Aboud, Said; Manji, Karim; Blomberg, Bjørn; Langeland, Nina; Roberts, Adam P. (Journal article; Peer reviewed, 2021)Background We aimed to characterise the genetic determinants and context of two meropenem-resistant clinical isolates of Acinetobacter baumannii isolated from children hospitalised with bloodstream infections in Dar es ... -
Molecular characterization of antibiotic resistant bacteria in newly HIV diagnosed adults in a community setting in Tanzania. Implications for infection prevention and control in HIV : Antibiotic resistant bacteria, HIV, Community, Sub-Saharan Africa
Manyahi, Joel (Doctoral thesis, 2022-08-26)Mennesker som lever med HIV-infeksjon i utviklingsland har økt risiko for å bli smittet med antibiotikaresistente bakterier. Høyere forbruk av antibiotika på grunn av HIV-relatert sykdom gir et seleksjonspress som kan føre ... -
Predominance of multidrug-resistant Salmonella Typhi genotype 4.3.1 with low-level ciprofloxacin resistance in Zanzibar
Onken, Annette; Moyo, Sabrina John; Miraji, Mohammed Khamis; Bohlin, Jon; Marijani, Msafiri; Manyahi, Joel; Kibwana, Kibwana Omar; Müller, Fredrik; Jenum, Pål; Abeid, Khamis Ali; Reimers, Marianne; Langeland, Nina; Mørch, Kristine; Blomberg, Bjørn (Journal article; Peer reviewed, 2024-04-17)Background: Typhoid fever is a common cause of febrile illness in low- and middle-income countries. While multidrug-resistant (MDR) Salmonella Typhi (S. Typhi) has spread globally, fluoroquinolone resistance has mainly ... -
Predominance of PVL-negative community-associated methicillin-resistant Staphylococcus aureus sequence type 8 in newly diagnosed HIV-infected adults, Tanzania
Manyahi, Joel; Moyo, Sabrina John; Aboud, Said; Langeland, Nina; Blomberg, Bjørn (Journal article; Peer reviewed, 2021)Difficult-to-treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are of concern in people living with HIV infection as they are more vulnerable to infection. We aimed to identify molecular ... -
Use of probiotics to reduce infections and death and prevent colonization with extended-spectrum beta-lactamase (ESBL)- producing bacteria among newborn infants in Tanzania (ProRIDE Trial): study protocol for a randomized controlled clinical trial
Kuwelker, Kanika; Langeland, Nina; Löhr, Iren Høyland; Gidion, Joshua; Manyahi, Joel; Moyo, Sabrina John; Blomberg, Bjørn; Klingenberg, Claus (Journal article; Peer reviewed, 2021)Background Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has emerged as an urgent global health threat and is by the World Health Organization ranked as priority 1 among pathogens in need of new ...