Blar i Bergen Open Research Archive på forfatter "Melvær, Giil Lasse"

Viser treff 1-11 av 11

    • Association Between Amygdala Volume and Trajectories of Neuropsychiatric Symptoms in Alzheimer’s Disease and Dementia With Lewy Bodies 

      Jaramillo-Jiménez, Alberto; Melvær, Giil Lasse; Tovar-Rios, Diego Alejandro; Borda, Miguel Germán; Ferreira, Daniel; Brønnick, Kolbjørn Kallesten; Oppedal, Ketil; Aarsland, Dag (Journal article; Peer reviewed, 2021)
      Introduction: The amygdala is implicated in psychiatric illness. Even as the amygdala undergoes significant atrophy in mild dementia, amygdala volume is underexplored as a risk factor for neuropsychiatric symptoms ...

    • Computed Tomography Assessment of Anatomic Graft Placement After ACL Reconstruction: A Comparative Study of Grid and Angle Measurements 

      Parkar, Anagha P.; Adriaensen, Miraude E.A.M.P.; Melvær, Giil Lasse; Solheim, Eirik (Peer reviewed; Journal article, 2019)
      Background: The anatomic placement of anterior cruciate ligament (ACL) grafts is often assessed with postoperative imaging. In clinical practice, graft angles are measured to indicate anatomic placement on magnetic resonance ...

    • Differentiating traits and states identifies the importance of chronic neuropsychiatric symptoms for cognitive prognosis in mild dementia 

      Melvær, Giil Lasse; Aarsland, Dag; Vik-Mo, Audun Osland (Journal article; Peer reviewed, 2021)
      Introduction Neuropsychiatric symptoms (NPS) in dementia are associated with poor cognitive outcomes in longitudinal studies. Whether this is due to differences in symptom burden between persons (BP) or changes within ...

    • The effect of drug-eluting stents on target lesion revascularization in native coronary arteries: results from the NORSTENT randomized study 

      Mølstad, Per; Nordrehaug, Jan Erik; Steigen, Terje; Melvær, Giil Lasse; Wilsgaard, Tom; Wiseth, Rune; Bønaa, Kaare Harald (Journal article; Peer reviewed, 2020)
      Background: The NORSTENT trial randomized 9,013 patients to percutaneous coronary intervention (PCI) with a drug-eluting stent (DES) or bare-metal stent (BMS) with 5-year follow-up. No difference was found in the composite ...

    • Effects of anthocyanin supplementation on serum lipids, glucose, markers of inflammation and cognition in adults with increased risk of dementia - A pilot study 

      Bergland, Anne Katrine; Sønnesyn, Hogne; Dalen, Ingvild; Rodriguez-Mateos, Ana; Berge, Rolf Kristian; Melvær, Giil Lasse; Rajendran, Lawrence; Siow, Richard; Tassotti, Michele; Larsen, Alf Inge; Aarsland, Dag (Peer reviewed; Journal article, 2019-06-11)
      Background: Anthocyanins may protect against cardiovascular related cognitive decline and dementia. Objective: Open-label study to measure changes in serum lipids, glucose, glycosylated hemoglobin (HbA1c), and markers of ...

    • Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF 

      Fossdal, Guri; Mjelle, Anders Batman; Wiencke, Kristine; Bjørk, Ida Torunn; Gilja, Odd Helge; Folseraas, Trine; Karlsen, Tom Hemming; Rosenberg, William; Melvær, Giil Lasse; Vesterhus, Mette Nåmdal (Journal article; Peer reviewed, 2021)
      Background & Aims Primary sclerosing cholangitis (PSC) is a progressive liver disease characterised by fluctuating liver biochemistries and highly variable disease progression. The Enhanced Liver Fibrosis (ELF®) test and ...

    • GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis 

      Cabral-Marques, Otavio; Marques, Alexandre; Melvær, Giil Lasse; De Vito, Roberta; Rademacher, Judith; Günther, Jeannine; Lange, Tanja; Humrich, Jens; Klapa, Sebastian; Schinke, Susanne; Schimke, Lena; Marschner, Gabriele; Pitann, Silke; Adler, Sabine; Dechend, Ralf; Muller, Dominik N.; Braicu, Ioana; Sehouli, Jalid; Schulze-Forster, Kai; Trippel, Tobias; Scheibenbogen, Carmen; Staff, Anne Cathrine; Mertens, Peter; Löbel, Madlen; Mastroianni, Justin; Plattfaut, Corinna; Gieseler, Frank; Dragun, Duska; Engelhardt, Barbara Elizabeth; Fernandez-Cabezudo, Maria; Ochs, Hans D; Al-Ramadi, Basel K; Lamprecht, Peter; Mueller, Antje; Heidecke, Harald; Riemekasten, Gabriela (Peer reviewed; Journal article, 2018-12-06)
      Autoantibodies have been associated with autoimmune diseases. However, studies have identified autoantibodies in healthy donors (HD) who do not develop autoimmune disorders. Here we provide evidence of a network of ...

    • Impaired glucose utilization in the brain of patients with delirium following hip fracture 

      Titlestad, Irit; Watne, Leiv; Caplan, Gideon A.; McCann, Adrian; Ueland, Per Magne; Neerland, Bjørn Erik; Myrstad, Marius; Halaas, Nathalie Bodd; Pollmann, Christian Thomas; Henjum, Kristi; Ranhoff, Anette Hylen; Solberg, Lene Bergendal; Figved, Wender; Cunningham, Colm; Melvær, Giil Lasse (Journal article; Peer reviewed, 2024)
      Alterations in brain energy metabolism have long been proposed as one of several neurobiological processes contributing to delirium. This is supported by previous findings of altered CSF lactate and neuron-specific enolase ...

    • Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging 

      Solvang, Stein-Erik Hafstad; Hodge, Allison; Watne, Leiv; Cabral-Marques, Otavio; Nordrehaug, Jan Erik; Giles, Graham G.; Dugué, Pierre-Antoine; Nygård, Ottar Kjell; Ueland, Per Magne; McCann, Adrian; Idland, Ane-Victoria; Midttun, Øivind; Ulvik, Arve; Halaas, Nathalie Bodd; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2022)
      The kynurenine pathway is implicated in aging, longevity, and immune regulation, but longitudinal studies and assessment of the cerebrospinal fluid (CSF) are lacking. We investigated tryptophan (Trp) and downstream kynurenine ...

    • Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia 

      Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Aarsland, Dag; Lange, Johannes; Ueland, Per Magne; McCann, Adrian; Midttun, Øivind; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2019)
      Introduction: Circulating tryptophan (Trp) and its downstream metabolites, the kynurenines, are potentially neuroactive. Consequently, they could be associated with neuropsychiatric symptoms and cognitive prognosis in ...

    • The Truth behind the Zeros: A New Approach to Principal Component Analysis of the Neuropsychiatric Inventory 

      Hellton, Kristoffer Herland; Cummings, Jeffrey; Vik-Mo, Audun Osland; Nordrehaug, Jan Erik; Aarsland, Dag; Selbæk, Geir; Melvær, Giil Lasse (Journal article; Peer reviewed, 2021)
      Psychiatric syndromes in dementia are often derived from the Neuropsychiatric Inventory (NPI) using principal component analysis (PCA). The validity of this statistical approach can be questioned, since the excessive ...