Blar i Bergen Open Research Archive på forfatter "Miettinen, Markus"
-
Leaflet Tensions Control the Spatio-Temporal Remodeling of Lipid Bilayers and Nanovesicles
Lipowsky, Reinhard; Ghosh, Rikhia; Satarifard, Vahid; Sreekumari, Aparna; Zamaletdinov, Miftakh; Różycki, Bartosz; Miettinen, Markus; Grafmüller, Andrea (Journal article; Peer reviewed, 2023)Biological and biomimetic membranes are based on lipid bilayers, which consist of two monolayers or leaflets. To avoid bilayer edges, which form when the hydrophobic core of such a bilayer is exposed to the surrounding ... -
Photocontrol of the β-Hairpin Polypeptide Structure through an Optimized Azobenzene-Based Amino Acid Analogue
Parlato, Raffaella; Volarić, Jana; Lasorsa, Alessia; Bagherpoor Helabad, Mahdi; Kobauri, Piermichele; Jain, Greeshma; Miettinen, Markus; Feringa, Ben L.; Szymanski, Wiktor; van der Wel, Patrick C. A. (Journal article; Peer reviewed, 2024)A family of neurodegenerative diseases, including Huntington’s disease (HD) and spinocerebellar ataxias, are associated with an abnormal polyglutamine (polyQ) expansion in mutant proteins that become prone to form amyloid-like ... -
Probing the elastic response of lipid bilayers and nanovesicles to leaflet tensions via volume per lipid
Zamaletdinov, Miftakh F.; Miettinen, Markus; Lipowsky, Reinhard (Journal article; Peer reviewed, 2023)Biological and biomimetic membranes are based on lipid bilayers, consisting of two monolayers or leaflets. One important but challenging physical parameter of these membranes is their tension. For a long time, this tension ... -
Quantitative Comparison against Experiments Reveals Imperfections in Force Fields’ Descriptions of POPC-Cholesterol Interactions
Javanainen, Matti; Heftberger, Peter; Madsen, Jesper J.; Miettinen, Markus; Pabst, Georg; Ollila, O. H. Samuli (Journal article; Peer reviewed, 2023)Cholesterol is a central building block in biomembranes, where it induces orientational order, slows diffusion, renders the membrane stiffer, and drives domain formation. Molecular dynamics (MD) simulations have played a ... -
Structure of POPC Lipid Bilayers in OPLS3e Force Field
Kurki, Milla; Poso, Antti; Bartos, Piia; Miettinen, Markus (Journal article; Peer reviewed, 2022)It is crucial for molecular dynamics simulations of biomembranes that the force field parameters give a realistic model of the membrane behavior. In this study, we examined the OPLS3e force field for the carbon−hydrogen ...