Blar i Bergen Open Research Archive på forfatter "Monnin, Audrey"
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Long-term persistence of mitochondrial DNA instability in HIV-exposed uninfected children during and after exposure to antiretroviral drugs and HIV
Desquiret-Dumas, Valérie; D’Ottavi, Morgana; Monnin, Audrey; Goudenège, David; Méda, Nicolas; Vizeneux, Amélie; Kankasa, Chipepo; Tylleskär, Thorkild; Bris, Céline; Procaccio, Vincent; Nagot, Nicolas; Van de Perre, Philippe; Reynier, Pascal; Molès, Jean-Pierre (Journal article; Peer reviewed, 2022)HIV-exposed uninfected (HEU) children show impaired health outcomes during childhood. A high rate of mitochondrial DNA (mtDNA) instability was reported in the blood of HEU at birth. We aimed to explore the relationship ... -
Longitudinal Follow-Up of Blood Telomere Length in HIV-Exposed Uninfected Children Having Received One Year of Lopinavir/Ritonavir or Lamivudine as Prophylaxis
Monnin, Audrey; Vizeneux, Amélie; Nagot, Nicolas; Eymard-Duvernay, Sabrina; Meda, Nicolas; Singata-Madliki, Mandisa; Ndeezi, Grace; Tumwine, James K; Kankasa, Chipepo; Goga, Ameena; Tylleskär, Thorkild; Van de Perre, Philippe; Molès, Jean-Pierre (Journal article; Peer reviewed, 2021)Telomere shortening can be enhanced upon human immunodeficiency virus (HIV) infection and by antiretroviral (ARV) exposures. The aim of this study was to evaluate the acute and long-term effect on telomere shortening of ... -
Mitochondrial DNA Instability Is Common in HIV-Exposed Uninfected Newborns
Monnin, Audrey; Desquiret-Dumas, Valérie; Meda, Nicolas; Goudenège, David; Bris, Céline; Kankasa, Chipepo; Singata-Madliki, Mandisa; Tylleskär, Thorkild; Procaccio, Vincent; Nagot, Nicolas; Van De Perre, Philippe; Reynier, Pascal; Molès, Jean-Pierre (Journal article; Peer reviewed, 2021)Worldwide, one million HIV-exposed uninfected (HEU) children are born yearly, and chronic health impairments have been reported in these children. Mitochondrial DNA (mtDNA) instability and altered mtDNA content have been ...