Blar i Bergen Open Research Archive på forfatter "Mosevoll, Knut Anders"
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Clinical Characteristics and Histopathology in Suspected Necrotizing Soft Tissue Infections
Gundersen, Ingunn Margareetta; Berget, Ellen; Haugland, Hans Kristian; Bruun, Trond; Almeland, Stian Kreken; Assmus, Jörg; Rath, Eivind; Norrby-Teglund, Anna; Skrede, Steinar; Mosevoll, Knut Anders (Journal article; Peer reviewed, 2022)Background Necrotizing soft tissue infections (NSTIs) are severe diseases with high morbidity and mortality. The diagnosis is challenging. Several guidelines recommend tissue biopsies as an adjunct diagnostic in routine ... -
Concomitant Hemophagocytic Lymphohistiocytosis and Cytomegalovirus Disease: A Case Based Systemic Review
Rolsdorph, Linn; Mosevoll, Knut Anders; Helgeland, Lars; Reikvam, Håkon (Journal article; Peer reviewed, 2022)Background: Hemophagocytic lymphohistiocytosis (HLH) is an immune mediated life-threatening condition. It is driven by an overactivation of the immune system and causes inflammatory tissue damage potentially leading to ... -
Coordination of Metabolism and Virulence Factors Expression of Extraintestinal Pathogenic Escherichia coli Purified from Blood Cultures of Patients with Sepsis
Pettersen, Veronika Kucharova; Mosevoll, Knut Anders; Lindemann, Paul Christoffer; Wiker, Harald G (Peer reviewed; Journal article, 2016-09)One of the trademarks of extraintestinal pathogenic Escherichia coli is adaptation of metabolism and basic physiology to diverse host sites. However, little is known how this common human pathogen adapts to permit survival ... -
COVID-19 myocarditis and postinfection Bell’s palsy
Dahl, Elin Hoffmann; Mosevoll, Knut Anders; Cramariuc, Dana; Vedeler, Christian Alexander; Blomberg, Bjørn (Journal article; Peer reviewed, 2021)Here we present the case of a 37-year-old previously healthy man who developed fever, headache and a unilateral, painful neck swelling while working offshore. He had no known contact with anyone with COVID-19; however, due ... -
Cytokine profiles in inflammation
Mosevoll, Knut Anders (Doctoral thesis, 2017-06-16)Inflammation is a complex tissue response to harmful stimuli such as microorganisms, damaged or dead cells, or irritants. The inflammatory process can be initiated by many different diseases, including thromboses, neoplastic ... -
Cytokines, adhesion molecules, and matrix metalloproteases as predisposing, diagnostic, and prognostic factors in venous thrombosis
Mosevoll, Knut Anders; Johansen, Silje; Wendelbo, Øystein; Nepstad, Ina; Bruserud, Øystein; Reikvam, Håkon (Peer reviewed; Journal article, 2018-05-22)The inflammatory response is a well-established part of, and a prerequisite for, venous thrombosis. To better understand the pathophysiology of venous thrombosis and to identify improved diagnostic biomarkers, further ... -
Febrile Neutropenia in Acute Leukemia. Epidemiology, Etiology, Pathophysiology and Treatment
Hansen, Bent Are; Wendelbo, Øystein; Bruserud, Øyvind; Hemsing, Anette Lodvir; Mosevoll, Knut Anders; Reikvam, Håkon (Journal article; Peer reviewed, 2020)Acute leukemias are a group of aggressive malignant diseases associated with a high degree of morbidity and mortality. An important cause of both the latter is infectious complications. Patients with acute leukemia are ... -
MicroRNA serum profiles and chronic graft-versus-host disease
Reikvam, Håkon; Vo, Anh Khoi; Johansen, Silje; Hemsing, Anette Lodvir; Haugland Solheim, Magne; Mosevoll, Knut Anders; Tvedt, Tor Henrik Anderson; Hatfield, Kimberley Joanne (Journal article; Peer reviewed, 2022)Chronic graft-versus-host disease (cGVHD) is the most common long-term complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). During the last decade, the interest of micro RNAs (miRNAs) in the ... -
Nekrotiserende bløtdelsinfeksjoner
Gundersen, Ingunn; Bruun, Trond; Almeland, Stian Kreken; Skutlaberg, Dag Harald; Nedrebø, Torbjørn; Rath, Eivind; Oppegaard, Oddvar; Guttormsen, Anne Berit; Norrby-Teglund, Anna; Mosevoll, Knut Anders; Skrede, Steinar (Journal article; Peer reviewed, 2024)Nekrotiserende bløtdelsinfeksjoner rammer hud, subkutant vev, overfladisk fascie, dyp fascie eller muskulatur. Infeksjonene er alvorlige, sprer seg hurtig og kan medføre omfattende vevstap. De er sjeldne, men har høy ... -
Patients with Bacterial Sepsis Are Heterogeneous with Regard to Their Systemic Lipidomic Profiles
Mosevoll, Knut Anders; Hansen, Bent-Are; Gundersen, Ingunn Margareetta; Reikvam, Håkon; Bruserud, Øyvind; Bruserud, Øystein; Wendelbo, Øystein (Journal article; Peer reviewed, 2023)Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. In the present study, we investigated the systemic/serum lipidomic profile at the time of hospital admission for ... -
Patients with treatment-requiring chronic graft versus host disease after allogeneic stem cell transplantation have altered metabolic profiles due to the disease and immunosuppressive therapy: Potential implication for biomarkers
Reikvam, Håkon; Grønningsæter, Ida Sofie; Mosevoll, Knut Anders; Lindås, Roald; Hatfield, Kimberley Joanne; Bruserud, Øystein (Journal article; Peer reviewed, 2018)Chronic graft versus host disease (cGVHD) is a common long-term complication after allogeneic hematopoietic stem cell transplantation. The objective of our study was to compare the metabolic profiles for allotransplant ... -
The Regulation of Neutrophil Migration in Patients with Sepsis: The Complexity of the Molecular Mechanisms and Their Modulation in Sepsis and the Heterogeneity of Sepsis Patients
Bruserud, Øystein; Mosevoll, Knut Anders; Bruserud, Øyvind; Reikvam, Håkon; Wendelbo, Øystein (Journal article; Peer reviewed, 2023)Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Common causes include gram-negative and gram-positive bacteria as well as fungi. Neutrophils are among the first ... -
Skåringsverktøy for tidlig oppdagelse av sepsis på sengepost
Karlsen, Elisabet Ethun; Rønsåsbjørg, Nora Almlid; Skrede, Steinar; Mosevoll, Knut Anders (Journal article; Peer reviewed, 2023)BAKGRUNN Sepsis er en av de vanligste årsakene til død i norske sykehus. Tilstanden er ofte oversett og behandlingen forsinket. Skåringsverktøy for å oppdage pasienter med sepsis er hyppigst undersøkt i akuttmottak, ... -
Systemic immune activation profiles in streptococcal necrotizing soft tissue infections: A prospective multicenter study
Rath, Eivind; Palma Medina, Laura M.; Jahagirdar, Sanjeevan; Mosevoll, Knut Anders; Damås, Jan Kristian; Madsen, Martin B.; Svensson, Mattias; Hyldegaard, Ole; Martins dos Santos, Vitor A.P.; Saccenti, Edoardo; Norrby-Teglund, Anna; Skrede, Steinar; Bruun, Trond (Journal article; Peer reviewed, 2023)Objective Early stages with streptococcal necrotizing soft tissue infections (NSTIs) are often difficult to discern from cellulitis. Increased insight into inflammatory responses in streptococcal disease may guide correct ... -
Systemic levels of the endothelium-derived soluble adhesion molecules endocan and E-selectin in patients with suspected deep vein thrombosis
Mosevoll, Knut Anders; Lindås, Roald; Wendelbo, Øystein; Bruserud, Øystein; Reikvam, Håkon (Peer reviewed; Journal article, 2014-09-30)The initial evaluation of patients with suspected deep vein thrombosis includes the use of biomarkers reflecting activation of the coagulation system. However, the thromboembolic process and neighboring inflammatory responses ... -
Systemic metabolomic profiles in adult patients with bacterial sepsis: Characterization of patient heterogeneity at the time of diagnosis
Mosevoll, Knut Anders; Hansen, Bent-Are; Gundersen, Ingunn Margareetta; Reikvam, Håkon; Bruserud, Øyvind; Bruserud, Øystein; Wendelbo, Øystein (Journal article; Peer reviewed, 2023-01-24)Sepsis is a dysregulated host response to infection that causes potentially life-threatening organ dysfunction. We investigated the serum metabolomic profile at hospital admission for patients with bacterial sepsis. The ... -
Thrombocytopaenia in the critically ill
Bruserud, Øyvind; Mosevoll, Knut Anders; Kristoffersen, Einar Klæboe; Kvåle, Reidar; Reikvam, Håkon (Journal article; Peer reviewed, 2021)