Browsing Bergen Open Research Archive by Author "Mrdalj, Jelena"
Now showing items 1-10 of 10
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Alerting and Circadian Effects of Short-Wavelength vs. Long-Wavelength Narrow-Bandwidth Light during a Simulated Night Shift
Sunde, Erlend; Pedersen, Torhild; Mrdalj, Jelena; Thun, Eirunn; Grønli, Janne; Harris, Anette; Bjorvatn, Bjørn; Waage, Siri; Skene, Debra J.; Pallesen, Ståle (Journal article; Peer reviewed, 2020)Light can be used to facilitate alertness, task performance and circadian adaptation during night work. Novel strategies for illumination of workplaces, using ceiling mounted LED-luminaires, allow the use of a range of ... -
Blue-enriched white light improves performance but not subjective alertness and circadian adaptation during three consecutive simulated night shifts
Sunde, Erlend; Pedersen, Torhild; Mrdalj, Jelena; Thun, Eirunn; Grønli, Janne; Harris, Anette; Bjorvatn, Bjørn; Waage, Siri; Skene, Debra J.; Pallesen, Ståle (Journal article; Peer reviewed, 2020)Use of blue-enriched light has received increasing interest regarding its activating and performance sustaining effects. However, studies assessing effects of such light during night work are few, and novel strategies for ... -
Bright light exposure during simulated night work improves cognitive flexibility
Sunde, Erlend; Mrdalj, Jelena; Pedersen, Torhild Thue; Bjorvatn, Bjørn; Grønli, Janne; Harris, Anette Kristoffersen; Waage, Siri; Pallesen, Ståle (Journal article; Peer reviewed, 2022)Night work leads to sleepiness and reduced vigilant attention during work hours, and bright light interventions may reduce such effects. It is also known that total sleep deprivation impairs cognitive flexibility as measured ... -
Cognitive function and brain plasticity in a rat model of shift work: role of daily rhythms, sleep and glucocorticoids
Marti, Andrea Rørvik; Pedersen, Torhild; Wisor, Jonathan P.; Mrdalj, Jelena; Holmelid, Øystein; Patil, Sudarshan; Meerlo, Peter; Bramham, Clive R.; Grønli, Janne (Journal article; Peer reviewed, 2020)Many occupations require operations during the night-time when the internal circadian clock promotes sleep, in many cases resulting in impairments in cognitive performance and brain functioning. Here, we use a rat model ... -
Early and Later Life Stress Alter Brain Activity and Sleep in Rats
Mrdalj, Jelena; Pallesen, Ståle; Milde, Anne Marita; Jellestad, Finn Konow; Murison, Robert; Ursin, Reidun; Bjorvatn, Bjørn; Grønli, Janne (Peer reviewed; Journal article, 2013-07-26)Exposure to early life stress may profoundly influence the developing brain in lasting ways. Neuropsychiatric disorders associated with early life adversity may involve neural changes reflected in EEG power as a measure ... -
The early life condition: Importance for sleep, circadian rhythmicity, behaviour and response to later life challenges
Mrdalj, Jelena (Doctoral thesis, 2014-12-09)Early life environment has a vast impact on development and adult functioning. Optimal brain development depends not only on genetic programming but also on specific external stimuli, where mother-infant relationships play ... -
Implication of NOTCH1 Gene in Susceptibility to Anxiety and Depression among Sexual Abuse Victims
Steine, Iris Mulders; Zayats, Tetyana; Stansberg, Christine; Pallesen, Ståle; Mrdalj, Jelena; Håvik, Bjarte; Soule, Jonathan; Haavik, Jan; Milde, Anne Marita; Skrede, Silje; Murison, Robert; Krystal, John H; Grønli, Janne (Peer reviewed; Journal article, 2016-12-13)Sexual abuse contributes to the development of multiple forms of psychopathology, including anxiety and depression, but the extent to which genetics contributes to these disorders among sexual abuse victims remains unclear. ... -
No escaping the rat race: simulated night shift work alters the time-of-day variation in BMAL1 translational activity in the prefrontal cortex
Marti, Andrea Rørvik; Patil, Sudarshan; Mrdalj, Jelena; Meerlo, Peter; Skrede, Silje; Pallesen, Ståle; Pedersen, Torhild; Bramham, Clive R.; Grønli, Janne (Peer reviewed; Journal article, 2017-10-04)Millions of people worldwide work during the night, resulting in disturbed circadian rhythms and sleep loss. This may cause deficits in cognitive functions, impaired alertness and increased risk of errors and accidents. ... -
Remote postconditioning by humoral factors in effluent from ischemic preconditioned rat hearts is mediated via PI3K/Akt-dependent cell-survival signaling at reperfusion
Breivik, Lars Ertesvåg; Helgeland, Erik; Aarnes, Eva-Katrine; Mrdalj, Jelena; Jonassen, Anne Kristin (Peer reviewed; Journal article, 2010-12-29)Short non-lethal ischemic episodes administered to hearts prior to (ischemic preconditioning, IPC) or directly after (ischemic postconditioning, IPost) ischemic events facilitate myocardial protection. Transferring coronary ... -
Shift in Food Intake and Changes in Metabolic Regulation and Gene Expression during Simulated Night-Shift Work: A Rat Model
Marti, Andrea Rørvik; Meerlo, Peter; Grønli, Janne; Hasselt, Sjoerd van; Mrdalj, Jelena; Pallesen, Ståle; Pedersen, Torhild; Henriksen, Tone Elise Gjøtterud; Skrede, Silje (Journal article; Peer reviewed, 2016)Night-shift work is linked to a shift in food intake toward the normal sleeping period, and to metabolic disturbance. We applied a rat model of night-shift work to assess the immediate effects of such a shift in food intake ...