• Brain Distribution of 10 cart Transcripts and Their Response to 4 Days of Fasting in Atlantic Salmon (Salmo salar L.) 

      Kalananthan, Tharmini; Gomes, Ana S.; Lai, Floriana; Tolås, Ingvill; Jordal, Ann-Elise O.; Norland, Sissel; Murashita, Koji; Rønnestad, Ivar (Journal article; Peer reviewed, 2021-10-25)
      Cocaine- and amphetamine-regulated transcript (CART) has been known to be involved in feeding and energy balance in mammals, acting as an anorexigenic neuropeptide in hypothalamus. In Atlantic salmon, little is known about ...
    • Effect of a plant-based low-fishmeal diet on digestive physiology in yellowtail Seriola quinqueradiata 

      Murashita, Koji; Matsunari, Hiroyuki; Fukada, Haruhisa; Suzuki, Nobuhiro; Furuita, Hirofumi; Oku, Hiromi; Rønnestad, Ivar; Yoshinaga, Hazuki; Yamamoto, Takeshi (Peer reviewed; Journal article, 2019)
      To characterize the effects of a plant-based low-fishmeal (LFM) diet on the digestive physiology of yellowtail, Seriola quinqueradiata, we prepared two isonitrogenous and isolipidic diets; an FM-based diet (diet Control, ...
    • Hypothalamic agrp and pomc mRNA Responses to Gastrointestinal Fullness and Fasting in Atlantic Salmon (Salmo salar, L.) 

      Kalananthan, Tharmini; Murashita, Koji; Rønnestad, Ivar; Ishigaki, Mitsumasa; Takahashi, Kota; Silva, Marta Sofia; Wakabayashi, Yuki; Lai, Floriana; Shimizu, Munetaka; Nilsen, Tom Ole; Martinez, Enrique Pino; Gomes, Ana S. (Journal article; Peer reviewed, 2020-02-11)
      The orexigenic agouti-related protein (AgRP) and the anorexigenic pro-opiomelanocortin (POMC) are crucial players in the control of feed intake in vertebrates, yet their role in teleosts has not been fully established. ...
    • Identification and characterization of the Atlantic salmon peptide transporter 1a 

      Gomes, Ana S.; Vacca, Francesca; Cinquetti, Raffaella; Murashita, Koji; Barca, Amilcare; Bossi, Elena; Rønnestad, Ivar; Verri, Tiziano (Journal article; Peer reviewed, 2020)
      Peptide transporter 1 (PepT1) mediates the uptake of dietary di-/tripeptides in vertebrates. However, in teleost fish gut, more than one PepT1-type transporter might operate, because of teleost-specific whole gen(om)e ...
    • Leptin receptor-deficient (knockout) zebrafish: Effects on nutrient acquisition 

      Del Vecchio, Gianmarco; Murashita, Koji; Verri, Tiziano; Gomes, Ana Cristina Da Silva; Rønnestad, Ivar (Journal article; Peer reviewed, 2021)
      In mammals, knockout of LEPR results in a hyperphagic, morbid obese, and diabetic phenotype, which supports that leptin plays an important role in the control of appetite and energy metabolism, and that its receptor, LEPR, ...
    • The Melanocortin System in Atlantic Salmon (Salmo salar L.) and Its Role in Appetite Control 

      Kalananthan, Tharmini; Lai, Floriana; Gomes, Ana S.; Murashita, Koji; Handeland, Sigurd O; Rønnestad, Ivar (Journal article; Peer reviewed, 2020-08-21)
      The melanocortin system is a key neuroendocrine network involved in the control of food intake and energy homeostasis in vertebrates. Within the hypothalamus, the system comprises two main distinct neuronal cell populations ...
    • Regional Expression of npy mRNA Paralogs in the Brain of Atlantic Salmon (Salmo salar, L.) and Response to Fasting 

      Tolås, Ingvill; Kalananthan, Tharmini; Gomes, Ana S.; Lai, Floriana; Norland, Sissel; Murashita, Koji; Rønnestad, Ivar (Journal article; Peer reviewed, 2021-08-26)
      Neuropeptide Y (NPY) is known as a potent orexigenic signal in vertebrates, but its role in Atlantic salmon has not yet been fully established. In this study, we identified three npy paralogs, named npya1, npya2, and npyb, ...