Browsing Bergen Open Research Archive by Author "Negård, Anne"
Now showing items 1-7 of 7
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Algebraic topology-based machine learning using MRI predicts outcomes in primary sclerosing cholangitis
Singh, Yashbir; Jons, William A.; Eaton, John E.; Vesterhus, Mette Nåmdal; Karlsen, Tom Hemming; Bjørk, Ida; Abildgaard, Andreas; Jørgensen, Kristin Kaasen; Folseraas, Trine; Little, Derek; Gulamhusein, Aliya F.; Petrovic, Kosta; Negård, Anne; Conte, Gian Marco; Sobek, Joseph D.; Jagtap, Jaidip; Venkatesh, Sudhakar K.; Gores, Gregory J.; LaRusso, Nicholas F.; Lazaridis, Konstantinos N.; Erickson, Bradley J. (Journal article; Peer reviewed, 2022)Background: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease that can lead to cirrhosis and hepatic decompensation. However, predicting future outcomes in patients with PSC is challenging. Our ... -
Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade
Ree, Anne Hansen; Høye, Eirik; Esbensen, Qin Ying; Røberg Beitnes, Ann-Christin; Negård, Anne; Bernklev, Linn; Tetlie, Linn Kruse; Fretland, Åsmund Avdem; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Nilsen, Hilde; Flatmark, Kjersti; Meltzer, Sebastian (Journal article; Peer reviewed, 2024)The randomized METIMMOX trial (NCT03388190) examined if patients with previously untreated, unresectable abdominal metastases from microsatellite-stable (MSS) colorectal cancer (CRC) might benefit from potentially immunogenic, ... -
Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
Meltzer, Sebastian; Negård, Anne; Bakke, Kine Mari; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Flatmark, Kjersti; Ree, Anne Hansen (Journal article; Peer reviewed, 2022)Background: Immune checkpoint blockade (ICB) results in radiologic tumour response dynamics that differ from chemotherapy efficacy measures and require an early signal of clinical utility. Methods: Previously untreated, ... -
First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial
Ree, Anne Hansen; Saltyte Benth, Jurate; Hamre, Hanne Mari; Kersten, Christian; Hofsli, Eva; Guren, Marianne; Sorbye, Halfdan; Johansen, Christin; Negård, Anne; Bjørnetrø, Tonje; Nilsen, Hilde; Berg, Jens Petter; Flatmark, Kjersti; Meltzer, Sebastian (Journal article; Peer reviewed, 2024)Background: We evaluated first-line treatment of metastatic microsatellite-stable colorectal cancer with short-course oxaliplatin-based chemotherapy alternating with immune checkpoint blockade. Methods: Patients were ... -
A novel MRI index for paraspinal muscle fatty infiltration: reliability and relation to pain and disability in lumbar spinal stenosis: results from a multicentre study
Aaen, Jørn Ståle; Storheim, Kjersti; Negård, Anne; Myklebust, Tor Åge; Grotle, Margreth; Hellum, Christian; Espeland, Ansgar; Anvar, Masoud D; Indrekvam, Kari; Weber, Clemens; Brox, Jens Ivar; Brisby, Helena; Hermansen, Erland; Banitalebi, Hasan (Journal article; Peer reviewed, 2022)Background Fatty infiltration of the paraspinal muscles may play a role in pain and disability in lumbar spinal stenosis. We assessed the reliability and association with clinical symptoms of a method for assessing fatty ... -
Preoperative fatty infiltration of paraspinal muscles assessed by MRI is associated with less improvement of leg pain 2 years after surgery for lumbar spinal stenosis
Banitalebi, Hasan; Hermansen, Erland; Hellum, Christian; Espeland, Ansgar; Storheim, Kjersti; Myklebust, Tor Åge; Indrekvam, Kari; Brisby, Helena; Weber, Clemens; Anvar, Masoud; Aaen, Jørn Ståle; Negård, Anne (Journal article; Peer reviewed, 2024)Abstract Purpose Fatty infiltration (FI) of the paraspinal muscles may associate with pain and surgical complications in patients with lumbar spinal stenosis (LSS). We evaluated the prognostic influence of MRI-assessed ... -
Reliability of preoperative MRI findings in patients with lumbar spinal stenosis
Banitalebi, Hasan; Espeland, Ansgar; Anvar, Masoud D; Hermansen, Erland; Hellum, Christian; Brox, Jens Ivar; Myklebust, Tor Åge; Indrekvam, Kari; Brisby, Helena; Weber, Clemens; Aaen, Jørn Ståle; Austevoll, Ivar Magne; Grundnes, Oliver; Negård, Anne (Journal article; Peer reviewed, 2022)Background Magnetic Resonance Imaging (MRI) is an important tool in preoperative evaluation of patients with lumbar spinal stenosis (LSS). Reported reliability of various MRI findings in LSS varies from fair to excellent. ...