• Addressing the clinical unmet needs in primary Sjögren's Syndrome through the sharing, harmonization and federated analysis of 21 European cohorts 

      Pezoulas, Vasileios C.; Goules, Andreas; Kalatzis, Fanis; Chatzis, Luke; Kourou, Konstantina D.; Venetsanopoulou, Aliki; Exarchos, Themis P.; Gandolfo, Saviana; Votis, Konstantinos; Zampeli, Evi; Burmeister, Jan; May, Thorsten; Marcelino Pérez, Manuel; Lishchuk, Iryna; Chondrogiannis, Thymios; Andronikou, Vassiliki; Varvarigou, Theodora; Filipovic, Nenad; Tsiknakis, Manolis; Baldini, Chiara; Bombardieri, Michele; Bootsma, Hendrika; Bowman, Simon J.; Shahnawaz Soyfoo, Muhammad; Parisis, Dorian; Delporte, Christine; Devauchelle-Pensec, Valérie; Pers, Jacques-Olivier; Dörner, Thomas; Bartoloni, Elena; Gerli, Roberto; Giacomelli, Roberto; Jonsson, Roland; Ng, Wan-Fai; Priori, Roberta; Ramos-Casals, Manuel; Sivils, Kathy; Skopouli, Fotini; Torsten, Witte; A. G. van Roon, Joel; Xavier, Mariette; De Vita, Salvatore; Tzioufas, Athanasios G.; Fotiadis, Dimitrios I. (Journal article; Peer reviewed, 2022)
      For many decades, the clinical unmet needs of primary Sjögren’s Syndrome (pSS) have been left unresolved due to the rareness of the disease and the complexity of the underlying pathogenic mechanisms, including the ...
    • Genetic variants at the RTP4/MASP1 locus are associated with fatigue in Scandinavian patients with primary Sjögren’s syndrome 

      Norheim, Katrine Brække; Imgenberg-Kreuz, Juliana; Alexsson, Andrei; Johnsen, Svein Joar Auglæn; Bårdsen, Kjetil; Brun, Johan Gorgas; Dehkordi, Rezvan Kiani; Theander, Elke; Mandl, Thomas; Jonsson, Roland; Ng, Wan-Fai; Lessard, Christopher J; Rasmussen, Astrid; Sivilis, Kathy; Rönnblom, Lars; Omdal, Roald (Journal article; Peer reviewed, 2021)
      Objectives Fatigue is common and severe in primary Sjögren’s syndrome (pSS). The aim of this study was to identify genetic determinants of fatigue in pSS through a genome-wide association study. Methods Patients with ...
    • Genome-wide association study identifies Sjögren’s risk loci with functional implications in immune and glandular cells 

      Khatri, Bhuwan; Tessneer, Kandice L.; Rasmussen, Astrid; Aghakhanian, Farhang; Reksten, Tove Ragna; Adler, Adam; Alevizos, Ilias; Anaya, Juan-Manuel; Aqrawi, Lara A.; Baecklund, Eva; Brun, Johan Gorgas; Bucher, Sara Magnusson; Eloranta, Maija-Leena; Engelke, Fiona; Forsblad-d’Elia, Helena; Glenn, Stuart B.; Hammenfors, Daniel; Imgenberg-Kreuz, Juliana; Jensen, Janicke Liaaen; Johnsen, Svein Joar Auglæn; Jonsson, Malin Viktoria; Kvarnström, Marika; Kelly, Jennifer A.; Li, He; Mandl, Thomas; Martín, Javier; Nocturne, Gaétane; Norheim, Katrine Brække; Palm, Øyvind; Skarstein, Kathrine; Stolarczyk, Anna M.; Taylor, Kimberly E.; Teruel, Maria; Theander, Elke; Venuturupalli, Swamy; Wallace, Daniel J.; Grundahl, Kiely M.; Hefner, Kimberly S.; Radfar, Lida; Lewis, David M.; Stone, Donald U.; Kaufman, C. Erick; Brennan, Michael T.; Guthridge, Joel M.; James, Judith A.; Scofield, R. Hal; Gaffney, Patrick M.; Criswell, Lindsey A.; Jonsson, Roland; Eriksson, Per; Bowman, Simon J.; Omdal, Roald; Rönnblom, Lars; Warner, Blake; Rischmueller, Maureen; Witte, Torsten; Farris, A. Darise; Mariette, Xavier; Alarcon-Riquelme, Marta E.; Shiboski, Caroline H.; Herlenius, Marie Elisabeth Wahren; Ng, Wan-Fai; Sivils, Kathy L.; Adrianto, Indra; Nordmark, Gunnel; Lessard, Christopher J. (Journal article; Peer reviewed, 2022)
      Sjögren’s disease is a complex autoimmune disease with twelve established susceptibility loci. This genome-wide association study (GWAS) identifies ten novel genome-wide significant (GWS) regions in Sjögren’s cases of ...
    • Weight of salivary gland ultrasonography compared to other items of the 2016 ACR/EULAR classification criteria for Primary Sjögren's syndrome 

      Jousse-Joulin, Sandrine; Gatineau, Florence; Baldini, Chiara; Baer, Alan; Barone, Francesca; Bootsma, Hendrika; Bowman, Simon Jonathan; Brito-Zerón, Pilar; Cornec, Divi; Dörner, Thomas; de Vita, Salvatore; Fisher, Benjamin A.; Hammenfors, Daniel; Jonsson, Malin V; Mariette, Xavier; Milić, Vera D.; Nakamura, Hideki; Ng, Wan-Fai; Nowak, Emmanuel; Ramos-Casals, Manuel; Rasmussen, Astrid; Séror, Raphaèle; Shiboski, Caroline H.; Nakamura, Takashi; Vissink, Arjan; Saraux, Alain; Devauchelle-Pensec, Valérie (Peer reviewed; Journal article, 2020)
      Objective: Major salivary gland ultrasonography (SGUS) is widely used for the diagnosis of primary Sjögren’s syndrome (pSS). Our objective was to assess the contribution of SGUS compared to other items of the 2016 ACR/EULAR ...