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Browsing Bergen Open Research Archive by Author "Nygård, Ottar Kjell"

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    • Assessment of Dietary Choline Intake, Contributing Food Items, and Associations with One-Carbon and Lipid Metabolites in Middle-Aged and Elderly Adults: The Hordaland Health Study 

      Van Parys, Anthea; Lysne, Vegard; Dierkes, Jutta; Nygård, Ottar Kjell; Øyen, Jannike; Vinknes, Kathrine Jørgensen; Karlsson, Therese; Haugsgjerd, Teresa Risan; Tell, Grethe S.; Ueland, Per Magne; Brække, Maria Sandvik (Journal article; Peer reviewed, 2022)
      Background: Choline is an essential nutrient for humans and is involved in various physiologic functions. Through its metabolite betaine, it is closely connected to the one-carbon metabolism, and the fat-soluble choline ...
    • Changes in lipoprotein particle subclasses, standard lipids, and apolipoproteins after supplementation with n-3 or n-6 PUFAs in abdominal obesity: A randomized double-blind crossover study 

      Grytten, Elise; Laupsa-Borge, Johnny; Bohov, Pavol; Bjørndal, Bodil; Strand, Elin; Skorve, Jon; Nordrehaug, Jan Erik; Berge, Rolf Kristian; Rostrup, Espen; Mellgren, Gunnar; Dankel, Simon N; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2021)
      Background & aims Marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), lower circulating levels of triacylglycerols (TAGs), and the plant-derived ...
    • Complement component 7 is associated with total- and cardiac death in chest-pain patients with suspected acute coronary syndrome 

      Aarsetøy, Reidun; Ueland, Thor; Aukrust, Pål; Michelsen, Annika Elisabet; Leon de la Fuente, Ricardo; Grundt, Magnea Heidi Jonsdottir; Staines, Harry; Nygård, Ottar Kjell; Nilsen, Dennis W.T. (Journal article; Peer reviewed, 2021)
      Background Complement activation has been associated with atherosclerosis, atherosclerotic plaque destabilization and increased risk of cardiovascular events. Complement component 7 (CC7) binds to the C5bC6 complex which ...
    • Food Sources Contributing to Intake of Choline and Individual Choline Forms in a Norwegian Cohort of Patients With Stable Angina Pectoris 

      Van Parys, Anthea; Karlsson, Therese; Vinknes, Kathrine; Olsen, Thomas; Øyen, Jannike; Dierkes, Jutta; Nygård, Ottar Kjell; Lysne, Vegard (Journal article; Peer reviewed, 2021)
      Background: Choline is an essential nutrient involved in a wide range of physiological functions. It occurs in water- and lipid-soluble forms in the body and diet. Foods with a known high choline content are eggs, beef, ...
    • Hepatic Energy Metabolism Underlying Differential Lipidomic Responses to High-Carbohydrate and High-Fat Diets in Male Wistar Rats 

      Dankel, Simon N; Bjørndal, Bodil; Lindquist, Carine; Grinna, Mari Lausund; Rossmann, Christine Renate; Bohov, Pavol; Nygård, Ottar Kjell; Hallstrom, Seth; Strand, Elin; Berge, Rolf Kristian (Journal article; Peer reviewed, 2021)
      Background Low-carbohydrate diets are suggested to exert metabolic benefits by reducing circulating triacylglycerol (TG) concentrations, possibly by enhancing mitochondrial activity. Objective We aimed to elucidate ...
    • No effect of plasma trimethylamine N-Oxide (TMAO) and plasma trimethyllysine (TML) on the association between choline intake and acute myocardial infarction risk in patients with stable angina pectoris 

      Van Parys, Anthea; Lysne, Vegard; Øyen, Jannike; Dierkes, Jutta; Nygård, Ottar Kjell (Journal article, 2020)
      Plasma concentrations of trimethylamine N-oxide (TMAO) have been linked to cardiovascular disease (CVD) risk and mortality. TMAO is formed through the bacterial conversion of trimethylamine which is obtained either directly ...
    • Primary cardiovascular risk prediction by LDL-cholesterol in Caucasian middle-aged and older adults: a joint analysis of three cohorts 

      Hilvo, Mika; Dhar, Indu; Lääperi, Mitja; Lysne, Vegard; Sulo, Gerhard; Tell, Grethe S.; Jousilahti, Pekka; Nygård, Ottar Kjell; Brenner, Hermann; Schöttker, Ben; Laaksonen, Reijo (Journal article; Peer reviewed, 2021)
      Aims Low-density lipoprotein cholesterol (LDL-C) is an established causal driver of atherosclerotic cardiovascular disease (ASCVD), but its performance and age-dependency as a biomarker for incident events and mortality ...
    • Trimethyllysine predicts all-cause and cardiovascular mortality in community-dwelling adults and patients with coronary heart disease 

      Bjørnestad, Espen Øglænd; Dhar, Indu; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Kristine Ringdal; Svenningsson, Mads Malm; Tell, Grethe Seppola; Ueland, Per Magne; Ørn, Stein; Sulo, Gerhard; Laaksonen, Reijo; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2021)
      Aims Trimethyllysine (TML) is involved in carnitine synthesis, serves as a precursor of trimethylamine N-oxide (TMAO) and is associated with cardiovascular events in patients with established coronary heart disease (CHD). ...
    • β-blocker use and risk of all-cause mortality in patients with coronary heart disease: effect modification by serum vitamin A 

      Dhar, Indu; Svingen, Gard Frodahl Tveitevåg; Olsen, Thomas; Lysne, Vegard; Bjørnestad, Espen Øglænd; Ueland, Per Magne; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2021)
      Aims  Blockade of β-adrenoceptors reduces sympathetic nervous system activity and improves survival in patients with heart failure with reduced left ventricular ejection fraction (HFrEF); however, any improvement in ...

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