• Assessment of Small Bowel Motility and SMA Blood Flow Studied with Transabdominal Ultrasound 

      Nylund, Kim; Gjengsto, Andreas Jessen; Volkmann, Hilde Løland Von; Gilja, Odd Helge (Journal article; Peer reviewed, 2022)
      Purpose: Gastrointestinal ultrasound (GIUS) is a noninvasive imaging technique that may be used to study physiological changes in the small bowel. The aim of the study was to investigate the feasibility of measuring blood ...
    • Bowel Perfusion Measured with Dynamic Contrast-enhanced Ultrasound Predicts Treatment Outcome in Patients with Crohn’s Disease 

      Sævik, Fredrik Eriksen; Nylund, Kim; Hausken, Trygve; Ødegaard, Svein; Gilja, Odd Helge (Peer reviewed; Journal article, 2014-09-02)
      Background: To improve management of patients with Crohn's disease (CD), objective measurements of the degree of local inflammation in the gastrointestinal wall are needed. Increased microvessel density and perfusion are ...
    • Defining Transabdominal Intestinal Ultrasound Treatment Response and Remission in Inflammatory Bowel Disease: Systematic Review and Expert Consensus Statement 

      Ilvermarl, Johan FKF; Hansen, Tawnya; Goodsall, Thomas M.; Seidelin, Jakob B.; Al-Farhan, Heba; Allocca, Mariangela; Begun, Jakob; Bryant, Robert V.; Carter, Dan; Christensen, Britt; Dubinsky, Marla C.; Gecse, Krisztina B.; Kucharzik, Torsten; Lu, Cathy; Maaser, Christian; Maconi, Giovanni; Nylund, Kim; Palmela, Carolina; Wilson, Stephanie; Wilkens, Rune (Journal article; Peer reviewed, 2021)
      Background and Aims No consensus exists on defining intestinal ultrasound response, transmural healing, or transmural remission in inflammatory bowel disease, nor clear guidance for optimal timing of assessment during ...
    • Development and Validation of a Simple Ultrasound Activity Score for Crohn’s Disease 

      Sævik, Fredrik Bjorvatn; Eriksen, Ragnar; Eide, Geir Egil; Gilja, Odd Helge; Nylund, Kim (Journal article; Peer reviewed, 2020-06-06)
      Background and Aims To improve management of patients with Crohn’s disease, objective measurements of disease activity are needed. Ileocolonoscopy is the current reference standard but has limitations that restrict repeated ...
    • Gastrointestinal Ultrasound Can Predict Endoscopic Activity in Crohn’s Disease 

      Sævik, Fredrik; Gilja, Odd Helge; Nylund, Kim (Journal article; Peer reviewed, 2020-04-24)
      Purpose To explore the ability of gastrointestinal ultrasound (GIUS) to separate patients in endoscopic remission from patients with active disease in a heterogeneous hospital cohort with Crohn’s disease (CD). Materials ...
    • Intestinal ultrasound early on in treatment follow-up predicts endoscopic response to anti-TNFα treatment in Crohn's disease 

      de Voogd, Floris; Bots, Steven; Gecse, Krisztina B.; Gilja, Odd Helge; D'Haens, Geert; Nylund, Kim (Journal article; Peer reviewed, 2022)
      Background To assess treatment response, objective measures are superior to clinical improvement in Crohn’s disease [CD]. Intestinal ultrasound [IUS] is an attractive, non-invasive alternative to endoscopy, demonstrating ...
    • Intestinal Ultrasound to Assess Disease Activity in Ulcerative Colitis: Development of a novel UC-Ultrasound Index 

      Bots, Steven; Nylund, Kim; Löwenberg, Mark; Gecse, Krisztina; D'Haens, Geert (Journal article; Peer reviewed, 2021)
      Introduction: Intestinal ultrasound [IUS] is useful to assess inflammation in ulcerative colitis [UC] patients. We aimed to develop an ultrasonographic activity index using endoscopy as the reference standard. Methods: ...
    • Plasma levels of guanylins are reduced in patients with Crohn’s disease 

      Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Tronstad, Rune Rose; Dizdar, Vernesa; Nylund, Kim; Hanevik, Kurt; Hausken, Trygve; Gilja, Odd Helge; Fiskerstrand, Torunn (Journal article; Peer reviewed, 2020)
      Background: Guanylin (GN) and uroguanylin (UGN) are endogenous ligands for the intestinal receptor guanylate cyclase C (GC-C), an important regulator of intestinal fluid homeostasis. Gene expression and protein levels of ...
    • Point-of-care ultrasound of the gastrointestinal tract 

      Gilja, Odd Helge; Nylund, Kim (Journal article; Peer reviewed, 2023)
      The widespread use of portable ultrasound scanners has promoted the concept of point of care ultrasound (POCUS), namely “ultrasound performed bedside and interpreted directly by the clinician.” The purpose of this short ...
    • Prolonged intestinal transit and diarrhea in patients with an activating GUCY2C mutation 

      Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Gilja, Odd Helge; Tronstad, Rune Rose; Sangnes, Dag André; Nortvedt, Ragnar; Hausken, Trygve; Dimcevski, Georg Gjorgji; Fiskerstrand, Torunn; Nylund, Kim (Peer reviewed; Journal article, 2017)
      Introduction: Increased intestinal hydration by activation of the epithelial enzyme linked receptor guanylate cyclase C (GC-C) is a pharmacological principle for treating constipation. Activating mutations in the GUCY2C ...
    • A Rare Case of Unilateral Renal Cortical Necrosis 

      Haaskjold, Yngvar Lunde; Nylund, Kim; Skrunes, Rannveig (Journal article; Peer reviewed, 2021)
      Unilateral cortical necrosis is a rare condition, and only described in a few case reports. We present a case of a previously healthy 24-year-old male with acute unilateral cortical necrosis, where contrast-enhanced ...
    • Ultrasound imaging for assessing functions of the GI tract 

      Steinsvik, Elisabeth Kjelsvik; Hatlebakk, Jan Gunnar; Hausken, Trygve; Nylund, Kim; Gilja, Odd Helge (Journal article; Peer reviewed, 2021)
      Objective: In the following review we outline how ultrasound can be used to measure physiological processes in the gastrointestinal tract. Approach: We have investigated the potential of ultrasound in assessing ...
    • Ultrasound in Crohn’s Disease - bowel wall characteristics and perfusion estimates using microbubbles 

      Nylund, Kim (Doctoral thesis, 2013-01-18)
      Crohn’s disease (CD) is a chronic inflammatory bowel disease which often presents early in life and sometimes can be debilitating. The patients need frequent diagnostic work-up to assess disease activity, location, extent ...