• Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation 

      van der Meer, Dennis; Cheng, Weiqiu; Rokicki, Jaroslav; Fernandez-Cabello, Sara; Shadrin, Alexey; Smeland, Olav Bjerkehagen; Ehrhart, Friederike; Guloksuz, Sinan; Pries, Lotta-Katrin; Lin, Bochao Danae; Rutten, Bart P F; Van Os, Jim; O’Donovan, Michael; Richards, Alexander L.; Steen, Nils Eiel; Djurovic, Srdjan; Westlye, Lars Tjelta; Andreassen, Ole; Kaufmann, Tobias Herbert (Journal article; Peer reviewed, 2024)
      Background Schizophrenia is a highly heritable brain disorder with a typical symptom onset in early adulthood. The 2-hit hypothesis posits that schizophrenia results from differential early neurodevelopment, predisposing ...
    • Genome-wide Association Analysis of Parkinson’s Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci 

      Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Bahrami, Shahram; Broce, Iris J.; Tesli, Martin Steen; Frei, Oleksandr; Wirgenes, Katrine Verena; O`Connell, Kevin; Krull, Florian; Bettella, Francesco; Steen, Nils Eiel; Sugrue, Leo P.; Wang, Yunpeng; Svenningsson, Per; Sharma, Manu; Pihlstrøm, Lasse; Toft, H. Mathias S.; O’Donovan, Michael; Djurovic, Srdjan; Desikan, Rahul S; Dale, Anders M.; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2021)
      Background Parkinson’s disease (PD) and schizophrenia (SCZ) are heritable brain disorders that involve dysregulation of the dopaminergic system. Epidemiological studies have reported potential comorbidity between the ...