Browsing Bergen Open Research Archive by Author "Oftedal, Linn Silje Wathne"
Now showing items 1-2 of 2
-
Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity Synergizing with Daunorubicin to Kill Leukemia Cells, but not Cardiomyocytes
Oftedal, Linn Silje Wathne; Selheim, Frode; Wahlsten, Matti; Sivonen, Kaarina; Døskeland, Stein Ove; Herfindal, Lars (Peer reviewed; Journal article, 2010-10-14)The potential of marine benthic cyanobacteria as a source of anticancer drug candidates was assessed in a screen for induction of cell death (apoptosis) in acute myeloid leukemia (AML) cells. Of the 41 marine cyanobacterial ... -
Marine Benthic Diatoms Contain Compounds Able to Induce Leukemia Cell Death and Modulate Blood Platelet Activity
Prestegard, Siv Kristin; Oftedal, Linn Silje Wathne; Coyne, Rosie Theresa; Nygård, Gyrid; Skjærven, Kaja Helvik; Knutsen, Gjert; Døskeland, Stein Ove; Herfindal, Lars (Peer reviewed; Journal article, 2009-11-18)In spite of the high abundance and species diversity of diatoms, only a few bioactive compounds from them have been described. The present study reveals a high number of mammalian cell death inducing substances in ...