Browsing Bergen Open Research Archive by Author "Olsen, Erik"

Now showing items 1-4 of 4

    • Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension 

      Thorstensen, Christian W.; Clasen, Per-Erik; Rognstad, Stine; Haldsrud, Renate; Føreid, Siri; Helstrøm, Trine; Bergland, Ola Undrum; Halvorsen, Lene Vernås; Aune, Arleen; Olsen, Erik; Brobak, Karl Marius; Høieggen, Aud; Gustavsen, Ingebjørg G.; Larstorp, Anne Cecilie Kjeldsen; Søraas, Camilla Lund; Opdal, Mimi Stokke (Journal article; Peer reviewed, 2022)
      We developed three ultra-high pressure liquid chromatography coupled to mass spectrometry detection (UHPLC-MS/MS) methods to quantify 25 antihypertensive drugs in serum samples. Patient-reported drug lists were collected, ...

    • Effect of Therapeutic Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial 

      Halvorsen, Lene Vernås; Søraas, Camilla Lund; Larstorp, Anne Cecilie Kjeldsen; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Liestøl, Knut; Aune, Arleen; Olsen, Erik; Brobak, Karl Marius; Bergland, Ola Undrum; Rognstad, Stine; Aarskog, Nikolai Ravn; Heimark, Sondre; Fadl Elmula, Fadl Elmula M.; Gerdts, Eva; Mo, Rune; Solbu, Marit Dahl; Opdal, Mimi Stokke; Kjeldsen, Sverre; Rostrup, Morten; Høieggen, Aud (Journal article; Peer reviewed, 2024)
      Background: Drug concentration in blood or urine is an acknowledged method to detect nonadherence. Observational studies suggest that informing patients about low or absent serum drug levels improves blood pressure (BP). ...

    • Gender Differences in Cardiac Organ Damage in Arterial Hypertension: Assessing the Role of Drug Nonadherence 

      Aune, Arleen; Ohldieck, Annabel Eide; Halvorsen, Lene Vernås; Brobak, Karl Marius; Olsen, Erik; Rognstad, Stine; Larstorp, Anne Cecilie Kjeldsen; Søraas, Camilla Lund; Rossebø, Anne Bjørhovde; Rösner, Assami; Grytaas, Marianne Aardal; Gerdts, Eva (Journal article; Peer reviewed, 2024)
      Introduction Cardiac organ damage like left ventricular (LV) hypertrophy and left atrial (LA) enlargement is more prevalent in women than men with hypertension, but the mechanisms underlying this gender difference remain ...

    • Novel biomarkers in patients with uncontrolled hypertension with and without kidney damage 

      Brobak, Karl Marius; Halvorsen, Lene Vernås; Aass, Hans Christian; Søraas, Camilla Lund; Aune, Arleen; Olsen, Erik; Bergland, Ola Undrum; Rognstad, Stine; Blom, Kjersti Benedicte; Birkeland, Jon Arne; Høieggen, Aud; Larstorp, Anne Cecilie Kjeldsen; Solbu, Marit Dahl (Journal article; Peer reviewed, 2024)
      Introduction Estimated glomerular filtration rate (eGFR) and urine albumin/creatinine ratio (ACR) are insensitive biomarkers for early detection of hypertension-mediated organ damage (HMOD). In this nationwide cross-sectional ...