Browsing Bergen Open Research Archive by Author "Oltedal, Satu"
Now showing items 1-3 of 3
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Influence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I–III colon cancers
Berg, Marianne; Guriby, Marianne; Nordgård, Oddmund; Nedrebø, Bjørn Steinar Olden; Ahlquist, Terje Cruickshank; Smaaland, Rune; Oltedal, Satu; Søreide, Jon Arne; Kørner, Hartwig; Lothe, Ragnhild A.; Søreide, Kjetil (Peer reviewed; Journal article, 2013)Lymph node (LN) harvest is influenced by several factors, including tumor genetics. Microsatellite instability (MSI) is associated with improved node harvest, but the association to other genetic factors is largely unknown. ... -
Molecular subtypes in stage II-III colon cancer defined by genomic instability: Early recurrence-risk associated with a high copy-number variation and loss of RUNX3 and CDKN2A
Berg, Marianne; Nordgård, Oddmund; Kørner, Hartwig; Oltedal, Satu; Smaaland, Rune; Søreide, Jon Arne; Søreide, Kjetil (Peer reviewed; Journal article, 2015-04-16)Objective: We sought to investigate various molecular subtypes defined by genomic instability that may be related to early death and recurrence in colon cancer. Methods: We sought to investigate various molecular subtypes ... -
Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing
Tjensvoll, Kjersti; Lapin, Morten; Gilje, Bjørnar; Garresori, Herish; Oltedal, Satu; Forthun, Rakel Brendsdal; Molven, Anders; Rozenholc, Yves; Nordgård, Oddmund (Journal article; Peer reviewed, 2022)Circulating tumor DNA (ctDNA) analysis has emerged as a clinically useful tool for cancer diagnostics and treatment monitoring. However, ctDNA detection is complicated by low DNA concentrations and technical challenges. ...