Browsing Bergen Open Research Archive by Author "Opdal, Mimi Stokke"

Now showing items 1-3 of 3

    • Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations 

      Bergland, Ola Undrum; Halvorsen, Lene Vernås; Søraas, Camilla Lund; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Rognstad, Stine; Brobak, Karl Marius; Aune, Arleen; Olsen, Eirik; Fauchald, Ylva; Heimark, Sondre; Thorstensen, Christian W; Liestøl, Knut; Solbu, Marit Dahl; Gerdts, Eva; Mo, Rune; Rostrup, Morten; Kjeldsen, Sverre; Høieggen, Aud; Opdal, Mimi Stokke; Fadl Elmula, Fadl Elmula M. (Journal article; Peer reviewed, 2021)
      Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in ...

    • Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension 

      Thorstensen, Christian W.; Clasen, Per-Erik; Rognstad, Stine; Haldsrud, Renate; Føreid, Siri; Helstrøm, Trine; Bergland, Ola Undrum; Halvorsen, Lene Vernås; Aune, Arleen; Olsen, Erik; Brobak, Karl Marius; Høieggen, Aud; Gustavsen, Ingebjørg G.; Larstorp, Anne Cecilie Kjeldsen; Søraas, Camilla Lund; Opdal, Mimi Stokke (Journal article; Peer reviewed, 2022)
      We developed three ultra-high pressure liquid chromatography coupled to mass spectrometry detection (UHPLC-MS/MS) methods to quantify 25 antihypertensive drugs in serum samples. Patient-reported drug lists were collected, ...

    • Effect of Therapeutic Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial 

      Halvorsen, Lene Vernås; Søraas, Camilla Lund; Larstorp, Anne Cecilie Kjeldsen; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Liestøl, Knut; Aune, Arleen; Olsen, Erik; Brobak, Karl Marius; Bergland, Ola Undrum; Rognstad, Stine; Aarskog, Nikolai Ravn; Heimark, Sondre; Fadl Elmula, Fadl Elmula M.; Gerdts, Eva; Mo, Rune; Solbu, Marit Dahl; Opdal, Mimi Stokke; Kjeldsen, Sverre; Rostrup, Morten; Høieggen, Aud (Journal article; Peer reviewed, 2024)
      Background: Drug concentration in blood or urine is an acknowledged method to detect nonadherence. Observational studies suggest that informing patients about low or absent serum drug levels improves blood pressure (BP). ...