Browsing Bergen Open Research Archive by Author "Opoka, Robert"
Now showing items 1-6 of 6
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Adherence to community versus facility-based delivery of monthly malaria chemoprevention with dihydroartemisinin-piperaquine for the post-discharge management of severe anemia in Malawian children: A cluster randomized trial
Nkosi-Gondwe, Thandile; Robberstad, Bjarne; Mukaka, Mavuto; Idro, Richard; Opoka, Robert; Banda, Saidon; Kühl, Melf-Jakob; Ter Kuile, Feiko O.; Blomberg, Bjørn; Phiri, Kamija S. (Journal article; Peer reviewed, 2021-08-10)Background: The provision of post-discharge malaria chemoprevention (PMC) in children recently admitted with severe anemia reduces the risk of death and re-admissions in malaria endemic countries. The main objective of ... -
Dihydroartemisinin-piperaquine or sulphadoxine-pyrimethamine for the chemoprevention of malaria in children with sickle cell anaemia in eastern and southern Africa (CHEMCHA): a protocol for a multi-centre, two-arm, double-blind, randomised, placebo-controlled superiority trial
Nkosi-Gondwe, Thandile; Robberstad, Bjarne; Opoka, Robert; Kalibbala, Dennis; Rujumba, Joseph; Galileya, Lufina Tsirizani; Akun, Pamela; Nambatya, Winnie; Ssenkusu, John; TerKuile, Feiko; Phiri, Kamija; Idro, Richard (Journal article; Peer reviewed, 2023)Background An estimated 300,000 babies are born with sickle cell anaemia (SCA) annually. Affected children have chronic ill health and suffer premature death. Febrile illnesses such as malaria commonly precipitate acute ... -
Economic evaluation of postdischarge malaria chemoprevention in preschool children treated for severe anaemia in Malawi, Kenya, and Uganda: A cost-effectiveness analysis
Kühl, Melf-Jakob; Gondwe, Thandile; Dhabangi, Aggrey; Kwambai, Titus K.; Mori, Amani Thomas; Opoka, Robert; John, C. Chandy; Idro, Richard; ter Kuile, Feiko O.; Phiri, Kamija S.; Robberstad, Bjarne (Journal article; Peer reviewed, 2022)Background Children hospitalised with severe anaemia in malaria-endemic areas are at a high risk of dying or being readmitted within six months of discharge. A trial in Kenya and Uganda showed that three months of ... -
Malaria Chemoprevention in the Postdischarge Management of Severe Anemia
Kwambai, Titus Kimutai; Dhabangi, Aggrey; Idro, Richard; Opoka, Robert; Watson, Victoria; Kariuki, Simon; Kuya, Nickline A.; Onyango, Eric D.; Otieno, Kephas; Samuels, Aaron M.; Desai, Meghna R.; Hensbroek, Michael Boele van; Wang, Duolao; John, Chandy C.; Robberstad, Bjarne; Phiri, Kamija S.; ter Kuile, Feiko (Journal article; Peer reviewed, 2020-12-03)BACKGROUND Children who have been hospitalized with severe anemia in areas of Africa in which malaria is endemic have a high risk of readmission and death within 6 months after discharge. No prevention strategy specifically ... -
Post-discharge malaria chemoprevention in children admitted with severe anaemia in malaria-endemic settings in Africa: a systematic review and individual patient data meta-analysis of randomised controlled trials
Phiri, Kamija S.; Khairallah, Carole; Kwambai, Titus Kimutai; Bojang, Kalifa; Dhabangi, Aggrey; Opoka, Robert; Idro, Richard; Stepniewska, Kasia; Hensbroek, Michael Boele van; Chandy, John; Robberstad, Bjarne; Greenwood, Brian; ter Kuile, Feiko O (Journal article; Peer reviewed, 2024)Background Severe anaemia is associated with high in-hospital mortality among young children. In malaria-endemic areas, surviving children also have an increased risk of mortality or readmission after hospital discharge. ... -
Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa
Okell, Lucy C.; Kwambai, Titus K.; Dhabangi, Aggrey; Khairallah, Carole; Nkosi-Gondwe, Thandile; Winskill, Peter; Opoka, Robert; Mousa, Andria; Kühl, Melf-Jakob; Lucas, Tim C.D.; Challenger, Joseph D.; Idro, Richard; Weiss, Daniel J.; Cairns, Matthew; ter Kuile, Feiko O.; Phiri, Kamija; Robberstad, Bjarne; Mori, Amani Thomas (Journal article; Peer reviewed, 2023)Children recovering from severe malarial anaemia (SMA) remain at high risk of readmission and death after discharge from hospital. However, a recent trial found that post-discharge malaria chemoprevention (PDMC) with ...