Blar i Bergen Open Research Archive på forfatter "Ousdal, Olga Therese"

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    • The association of PTSD symptom severity with amygdala nuclei volumes in traumatized youths 

      Ousdal, Olga Therese; Milde, Anne Marita; Hafstad, Gertrud Sofie; Hodneland, Erlend; Dyb, Grete; Craven, Alexander R.; Melinder, Annika Maria D; Endestad, Tor; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020)
      The amygdala is a core component in neurobiological models of stress and stress-related pathologies, including post-traumatic stress disorder (PTSD). While numerous studies have reported increased amygdala activity following ...

    • Brain changes induced by electroconvulsive therapy are broadly distributed 

      Ousdal, Olga Therese; Argyelan, Miklos; Narr, Katherine L.; Abbott, Christopher; Wade, Benjamin; Vandenbulcke, Mathieu; Urretavizcaya, Mikel; Tendolkar, Indira; Takamiya, Akihiro; Stek, Max L.; Soriano-Mas, Carles; Redlich, Ronny; Paulson, Olaf B.; Oudega, Mardien L.; Opel, Nils; Nordanskog, Pia; Kishimoto, Taishiro; Kämpe, Robin; Jørgensen, Anders; Hanson, Lars G.; Hamilton, J. Paul; Espinoza, Randall; Emsell, Louise; van Eijndhoven, Philip; Dols, Annemieke; Dannlowski, Udo; Cardoner, Narcis; Bouckaert, Filip; Anand, Amit; Bartsch, Hauke; Kessler, Ute; Ødegaard, Ketil Joachim; Dale, Anders; Oltedal, Leif (Peer reviewed; Journal article, 2020-03-01)
      Background Electroconvulsive therapy (ECT) is associated with volumetric enlargements of corticolimbic brain regions. However, the pattern of whole-brain structural alterations following ECT remains unresolved. Here, we ...

    • Diffusion Tensor Imaging Before and 3 Months After Concentrated Exposure Response Prevention in Obsessive-Compulsive Disorder 

      Brecke, Vilde; Thorsen, Anders Lillevik; Ousdal, Olga Therese; Vriend, Chris; Alnæs, Dag; Hagen, Kristen; Hansen, Bjarne; Kvale, Gerd; van den Heuvel, Odile A (Journal article; Peer reviewed, 2021)
      Background: Subtle differences in white matter microstructure have been found in obsessive-compulsive disorder (OCD) compared to controls using diffusion tensor imaging (DTI), but it is unclear if and how this change after ...

    • Disentangling Within- and Between-Person Effects During Response Inhibition in Obsessive-Compulsive Disorder 

      Hagland, Pernille; Thorsen, Anders Lillevik; Ousdal, Olga Therese; Gjestad, Rolf; de Wit, Stella J.; Hansen, Bjarne Kristian Aaslie; Hagen, Kristen; Kvale, Gerd; van den Heuvel, Odile A. (Journal article; Peer reviewed, 2021)
      Background: Obsessive-compulsive disorder (OCD) has been related to worse performance, abnormal brain activity, and functional connectivity during response inhibition. Whether these findings are indications of stable traits ...

    • Effects of Bergen 4-Day Treatment on Resting-State Graph Features in Obsessive-Compulsive Disorder 

      Thorsen, Anders Lillevik; Vriend, Chris; de Wit, Stella J.; Ousdal, Olga Therese; Hagen, Kristen; Hansen, Bjarne; Kvale, Gerd; van den Heuvel, Odile A (Journal article; Peer reviewed, 2020)
      Background Exposure and response prevention is an effective treatment for obsessive-compulsive disorder (OCD), but it is unclear how symptom reduction is related to changes in the brain. We aimed to determine the effects ...

    • Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression 

      Argyelan, Miklos; Deng, Zhi-De; Ousdal, Olga Therese; Oltedal, Leif; Angulo, Brian; Baradits, Mate; Spitzberg, Andrew J.; Kessler, Ute; Sartorius, Alexander; Dols, Annemiek; Narr, Katherine L.; Espinoza, Randall; van Waarde, Jeroen A.; Tendolkar, Indira; van Eijndhoven, Philip; van Wingen, Guido A.; Takamiya, Akihiro; Kishimoto, Taishiro; Jorgensen, Martin B.; Jorgensen, Anders; Paulson, Olaf B.; Yrondi, Antoine; Péran, Patrice; Soriano-Mas, Carles; Cardoner, Narcis; Cano, Marta; van Diermen, Linda; Schrijvers, Didier; Belge, Jean-Baptiste; Emsell, Louise; Bouckaert, Filip; Vandenbulcke, Mathieu; Kiebs, Maximilian; Hurlemann, René; Mulders, Peter Cr.; Redlich, Ronny; Dannlowski, Udo; Erhan, Kavakbasi; Kritzer, Michael D.; Ellard, Kristen K.; Camprodon, Joan A.; Petrides, Georgios; Malhotra, Anil K.; Abbott, Christopher C. (Journal article; Peer reviewed, 2023)
      Neurostimulation is a mainstream treatment option for major depression. Neuromodulation techniques apply repetitive magnetic or electrical stimulation to some neural target but significantly differ in their invasiveness, ...

    • Elevated body weight modulates subcortical volume change and associated clinical response following electroconvulsive therapy 

      Opel, Nils; Narr, Katherine L; Abbott, Christopher; Argyelan, Miklos; Espinoza, Randall; Emsell, Louise; Bouckaert, Filip; Sienaert, Pascal; Vandenbulcke, Mathieu; Nordanskog, Pia; Repple, Jonathan; Kavakbasi, Erhan; Jorgensen, Martin B.; Paulson, Olaf B.; Hanson, Lars G.; Dols, Annemieke; van Exel, Eric; Oudega, Mardien L.; Takamiya, Akihiro; Kishimoto, Taishiro; Ousdal, Olga Therese; Haavik, Jan; Hammar, Åsa Karin; Ødegaard, Ketil Joachim; Kessler, Ute; Bartsch, Hauke; Dale, Anders M.; Baune, Bernhard T; Dannlowski, Udo; Oltedal, Leif; Redlich, Ronny (Journal article; Peer reviewed, 2021)
      Background: Obesity is a frequent somatic comorbidity of major depression, and it has been associated with worse clinical outcomes and brain structural abnormalities. Converging evidence suggests that electroconvulsive ...

    • The human amygdala encodes value and space during decision making 

      Ousdal, Olga Therese; Specht, Karsten; Server, Andres; Andreassen, Ole Andreas; Dolan, Ray J.; Jensen, Jimmy Kristian (Peer reviewed; Journal article, 2014-11-01)
      Valuable stimuli are invariably localized in space. While our knowledge regarding the neural networks supporting value assignment and comparisons is considerable, we lack a basic understanding of how the human brain ...

    • Inhibitory control as possible risk and/or resilience factor for the development of trauma related symptoms–a study of the Utøya terror attack survivors 

      Hammar, Åsa Karin; Schmid, Marit Therese; Petersdotter, Linn; Ousdal, Olga Therese; Milde, Anne Marita (Journal article; Peer reviewed, 2023)
      PTSD symptomatology is known to be associated with executive dysfunction. Inhibitory control is a core component of executive functioning, and inhibitory skills are essential both for adequate functioning in everyday life ...

    • Longitudinal changes in neurometabolite concentrations in the dorsal anterior cingulate cortex after concentrated exposure therapy for obsessive-compulsive disorder 

      de Joode, Niels T.; Thorsen, Anders Lillevik; Vester, Eline L.; Vriend, Chris; Pouwels, Petra J.W.; Hagen, Kristen; Ousdal, Olga Therese; Hansen, Bjarne Kristian Aaslie; Kvale, Gerd; van den Heuvel, Odile A. (Journal article; Peer reviewed, 2021)
      Background The dorsal anterior cingulate cortex (dACC) plays an important role in the pathophysiology of obsessive-compulsive disorder (OCD) due to its role in error processing, cognitive control and emotion regulation. ...

    • Longitudinal stability of the brain functional connectome is associated with episodic memory performance in aging 

      Ousdal, Olga Therese; Kaufmann, Tobias; Kolskår, Knut-Kristian; Vik, Alexandra; Wehling, Eike; Lundervold, Astri; Lundervold, Arvid; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2020)
      The brain functional connectome forms a relatively stable and idiosyncratic backbone that can be used for identification or “fingerprinting” of individuals with a high level of accuracy. While previous cross‐sectional ...

    • Neural Substrates of Psychotic Depression: Findings From the Global ECT-MRI Research Collaboration 

      Takamiya, Akihiro; Dols, Annemiek; Emsell, Louise; Abbott, Christopher; Yrondi, Antoine; Soriano-Mas, Carles; Jørgensen, Martin Balslev; Nordanskog, Pia; Rhebergen, Didi; van Exel, Eric; Oudega, Mardien L.; Bouckaert, Filip; Vandenbulcke, Mathieu; Sienaert, Pascal; Péran, Patrice; Cano, Marta; Cardoner, Narcis; Jørgensen, Anders; Paulson, Olaf B.; Hamilton, Paul; Kampe, Robin; Bruin, Willem; Bartsch, Hauke; Ousdal, Olga Therese; Kessler, Ute; van Wingen, Guido; Oltedal, Leif; Kishimoto, Taishiro (Journal article; Peer reviewed, 2021)
      Psychotic major depression (PMD) is hypothesized to be a distinct clinical entity from nonpsychotic major depression (NPMD). However, neurobiological evidence supporting this notion is scarce. The aim of this study is to ...

    • The Neurobiological Effects of Electroconvulsive Therapy Studied Through Magnetic Resonance: What Have We Learned, and Where Do We Go? 

      Ousdal, Olga Therese; Brancati, Giulio E.; Kessler, Ute; Erchinger, Vera; Dale, Anders M.; Abbott, Christopher; Oltedal, Leif (Journal article; Peer reviewed, 2021)
      Electroconvulsive therapy (ECT) is an established treatment choice for severe, treatment-resistant depression, yet its mechanisms of action remain elusive. Magnetic resonance imaging (MRI) of the human brain before and ...

    • Short and long-term effects of single and multiple sessions of electroconvulsive therapy on brain gray matter volumes 

      Brancati, Giulio Emilio; Brekke, Njål; Bartsch, Hauke; Sørhaug, Ole Johan Evjenth; Ousdal, Olga Therese; Hammar, Åsa Karin; Schuster, Peter Moritz; Ødegaard, Ketil Joachim; Kessler, Ute; Oltedal, Leif (Journal article; Peer reviewed, 2021)
      Background: Electroconvulsive therapy (ECT) has been shown to induce broadly distributed cortical and subcortical volume increases, more prominently in the amygdala and the hippocampus. Structural changes after one ECT ...

    • Stable inhibition-related inferior frontal hypoactivation and fronto-limbic hyperconnectivity in obsessive–compulsive disorder after concentrated exposure therapy 

      Thorsen, Anders Lillevik; de Wit, Stella J.; Hagland, Pernille; Ousdal, Olga Therese; Hansen, Bjarne; Hagen, Kristen; Kvale, Gerd; van den Heuvel, Odile A (Journal article; Peer reviewed, 2020)
      Response inhibition has previously been suggested as an endophenotype for obsessive–compulsive disorder (OCD), evidenced by studies showing worse task performance, and altered task-related activation and connectivity. ...

    • Task-based functional connectivity reveals aberrance with the salience network during emotional interference in late-life depression 

      Almdahl, Ina Selseth; Martinussen, Liva Jenny; Ousdal, Olga Therese; Kraus, Miroslawa; Sowa, Piotr; Agartz, Ingrid; Korsnes, Maria Stylianou (Journal article; Peer reviewed, 2023)
      Objectives Late-life depression (LLD) is a common and debilitating disorder. Previously, resting-state studies have revealed abnormal functional connectivity (FC) of brain networks in LLD. Since LLD is associated with ...