Blar i Bergen Open Research Archive på forfatter "Paunas, Flavia Teodora Ioana"
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Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli
Paunas, Flavia Teodora Ioana; Finne, Kenneth; Leh, Sabine Maria; Osman, Tarig Al-Hadi; Marti, Hans-Peter; Berven, Frode; Vikse, Bjørn Egil (Peer reviewed; Journal article, 2019-11-14)Background IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN. Methods In ... -
Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy
Paunas, Flavia Teodora Ioana; Finne, Kenneth; Leh, Sabine Maria; Marti, Hans-Peter; Mollnes, Tom Eirik; Berven, Frode; Vikse, Bjørn Egil (Peer reviewed; Journal article, 2017-08-14)Background: The clinical course of IgA nephropathy (IgAN) is variable and complement activation may predict prognosis. The present study investigated whether glomerular abundance of complement proteins associates with ... -
Glomerular and tubular proteome markers of progressive IgA nephropathy
Paunas, Flavia Teodora Ioana (Doctoral thesis, 2022-06-03)Background: IgA nephropathy (IgAN) is the most common glomerulonephritis in the world, with a clinical course ranging from asymptomatic non-progressive to aggressive and progressive disease to kidney failure. The exact ... -
Glomerular transcriptomics predicts long term outcome and identifies therapeutic strategies for patients with assumed benign IgA nephropathy
Rivedal, Mariell Lossius; Mikkelsen, Håvard; Marti, Hans Peter; Liu, Lili; Kiryluk, Krzysztof; Knoop, Thomas; Bjørneklett, Rune Oskar; Haaskjold, Yngvar Lunde; Furriol Palmer, Jessica; Leh, Sabine; Paunas, Flavia Teodora Ioana; Babickova, Janka; Scherer, Andreas; Serre, Camille Julia; Eikrem, Øystein Solberg; Strauss, Philipp (Journal article; Peer reviewed, 2024)Some patients diagnosed with benign IgA nephropathy (IgAN) develop a progressive clinical course, not predictable by known clinical or histopathological parameters. To assess if gene expression can differentiate between ... -
Proteomic signature of tubulointerstitial tissue predicts prognosis in IgAN
Paunas, Flavia Teodora Ioana; Finne, Kenneth; Leh, Sabine; Marti, Hans Peter; Berven, Frode Steingrimsen; Vikse, Bjørn Egil (Journal article; Peer reviewed, 2022-03-24)Background: IgA nephropathy (IgAN) is associated with a significant risk of progression to kidney failure. Tubular atrophy is an established important risk factor for progressive disease, but few studies have investigated ...