Browsing Bergen Open Research Archive by Author "Pedersen, Kjetil Boye"
Now showing items 1-3 of 3
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Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
Namløs, Heidi Maria; Khelik, Ksenia; Nakken, Sigve; Vodak, Daniel; Hovig, Eivind; Myklebost, Ola; Pedersen, Kjetil Boye; Meza, Leonardo Zepeda (Journal article; Peer reviewed, 2023)Patients with localised, high-risk gastrointestinal stromal tumours (GIST) benefit from adjuvant imatinib treatment. Still, approximately 40% of patients relapse within 3 years after adjuvant therapy and the clinical and ... -
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
Peneder, Peter; Stütz, Adrian M.; Surdez, Didier; Krumbholz, Manuela; Semper, Sabine; Chicard, Mathieu; Sheffield, Nathan C.; Pierron, Gaelle; Lapouble, Eve; Tötzl, Marcus; Ergüner, Bekir; Barreca, Daniele; Rendeiro, André F.; Agaimy, Abbas; Boztug, Heidrun; Engstler, Gernot; Dworzak, Michael; Bernkopf, Marie; Taschner-Mandl, Sabine; Ambros, Inge M.; Myklebost, Ola; Marec-Bérard, Perrine; Burchill, Susan A.; Brennan, Bernadette; Strauss, Sandra; Whelan, Jeremy; Schleiermacher, Gudrun; Schaefer, Christiane; Dirksen, Uta; Hutter, Caroline; Pedersen, Kjetil Boye; Ambros, Peter F.; Delattre, Olivier; Metzler, Markus; Bock, Christoph; Tomazou, Eleni M. (Journal article; Peer reviewed, 2021)Sequencing of cell-free DNA in the blood of cancer patients (liquid biopsy) provides attractive opportunities for early diagnosis, assessment of treatment response, and minimally invasive disease monitoring. To unlock ... -
Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
Pedersen, Kjetil Boye; Jacob, Havjin; Frikstad, Kari-Anne; Nesland, Jahn M; Mælandsmo, Gunhild; Dahl, Olav; Nesbakken, Arild; Flatmark, Kjersti (Peer reviewed; Journal article, 2016-08)Current clinical algorithms are unable to precisely predict which colorectal cancer patients would benefit from adjuvant chemotherapy, and there is a need for novel biomarkers to improve the selection of patients. The ...