Blar i Bergen Open Research Archive på forfatter "Pedersen, Linda Margareth"

Viser treff 1-6 av 6

    • The causal role of smoking on the risk of hip or knee replacement due to primary osteoarthritis: a Mendelian randomisation analysis of the HUNT study 

      Johnsen, Marianne Bakke; Vie, Gunnhild Åberge; Winsvold, Bendik K S; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Gabrielsen, Maiken Elvestad; Pedersen, Linda Margareth; Hellevik, Alf Inge; Langhammer, Arnulf; Furnes, Ove; Flugsrud, Gunnar B; Skorpen, Frank; Romundstad, Pål Richard; Storheim, Kjersti; Nordsletten, Lars; Zwart, John-Anker (Peer reviewed; Journal article, 2017-06)
      Objective: Smoking has been associated with a reduced risk of hip and knee osteoarthritis (OA) and subsequent joint replacement. The aim of the present study was to assess whether the observed association is likely to be ...

    • COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study 

      Jacobsen, Kaya Kvarme; Børte, Sigrid; Laborie, Lene Bjerke; Kristiansen, Hege; Schäfer, Annette; Gundersen, Trude; Zayats, Tetyana; Winsvold, Bendik Kristoffer Slagsvold; Karen, Rosendahl; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Fors, Egil Andreas; Kristoffersen, Espen Saxhaug; Heuch, Ingrid; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Nielsen, Jonas B.; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars G; Thomas, Laurent Francois; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Lie, Marie U.; Stensland, Synne; Zhou, Wei (Journal article; Peer reviewed, 2024)
      Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30% of all total hip arthroplasties (THAs) in adults ...

    • Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement 

      Vigeland, Maria Dehli; Flåm, Siri Tennebø; Vigeland, Magnus Dehli; Espeland, Ansgar; Kristoffersen, Per Martin; Vetti, Nils; Wigemyr, Monica; Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Schistad, Ellina Iordanova; Haugen, Anne Julsrud; Johanessen, Anne Froholdt; Skouen, Jan Sture; Zwart, John Anker Henrik; Storheim, Kjersti; Pedersen, Linda Margareth; Lie, Benedicte Alexandra (Journal article; Peer reviewed, 2022-01-07)
      Disability and distress caused by chronic low back pain (LBP) lacking clear pathoanatomical explanations cause huge problems both for patients and society. A subgroup of patients has Modic changes (MC), identifiable by MRI ...

    • Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study) 

      Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Gervin, Kristina; Pripp, Are Hugo; Skouen, Jan Sture; Schistad, Elina Iordanova; Pedersen, Linda Margareth; Wigemyr, Monica; Selmer, Kaja Kristine; Dalsbotten Aass, Hans Christian; Goll, Guro Løvik; Brox, Jens Ivar; Espeland, Ansgar; Grøvle, Lars; Zwart, John Anker Henrik; Storheim, Kjersti (Journal article; Peer reviewed, 2023)
      Objective: Randomized trials testing the effect of antibiotics for chronic low back pain (LBP) with vertebral bone marrow changes on MRI (Modic changes) report inconsistent results. A proposed explanation is subgroups with ...

    • Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools 

      Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik K S; O'Connell, Kevin S; Frei, Oleksandr; Shadrin, Alexey; Cheng, Weiqiu; Bettella, Francesco; Rødevand, Linn; Ødegaard, Ketil Joachim; Fan, Chun C; Pirinen, Matti J; Hautakangas, Heidi M; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Tronvik, Erling Andreas; Kristoffersen, Espen Saxhaug; Zwart, John Anker Henrik; Nielsen, Jonas Bille; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Stovner, Lars Jacob; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir Lingaas; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole (Journal article; Peer reviewed, 2022)
      Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are ...

    • Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes 

      Vigeland, Maria Dehli; Flåm, Siri Tennebø; Vigeland, Magnus Dehli; Espeland, Ansgar; Zucknick, Manuela; Wigemyr, Monica; Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Zwart, John Anker Henrik; Storheim, Kjersti; Pedersen, Linda Margareth; Selmer, Kaja Kristine; Lie, Benedicte Alexandra; Gervin, Kristina (Journal article; Peer reviewed, 2023-07-21)
      Long-term antibiotics are prescribed for a variety of medical conditions, recently including low back pain with Modic changes. The molecular impact of such treatment is unknown. We conducted longitudinal transcriptome and ...