Browsing Bergen Open Research Archive by Author "Pu, Jinjun"

Now showing items 1-2 of 2

Propofol alleviates DNA damage induced by oxygen glucose deprivation and reperfusion via FoxO1 nuclear translocation in H9c2 cells

Zhou, Dandan; Zhuang, Jinqiang; Wang, Yihui; Zhao, Dandan; Zhao, Lidong; Zhu, Shun; Pu, Jinjun; Yin, Ming; Zhang, Hongyu; Wang, Zejian; Hong, Jiang (Peer reviewed; Journal article, 2019-03-15)

Ischemia/reperfusion (I/R) injury induces irreversible oxidative stress damage to the cardiac myocytes. Many studies have revealed that propofol alleviates the important organelle-mediated injury from oxidative stress in ...
Propofol ameliorates H9c2 cells apoptosis induced by oxygen glucose deprivation and reperfusion injury via inhibiting high levels of mitochondrial fusion and fission

Zhao, Lidong; Zhuang, Jinqiang; Wang, Yihui; Zhou, Dandan; Zhao, Dandan; Zhu, Shun; Pu, Jinjun; Zhang, Hongyu; Yin, Ming; Zhao, Wenjuan; Wang, Zejian; Hong, Jiang (Peer reviewed; Journal article, 2019-02-12)

Background: The cardioprotective effect of propofol on ischemia-reperfusion injury (I/R injury) is partly due to suppressing apoptosis. Mitochondrial dynamics are also involved in apoptosis. Mitochondrial fusion and fission ...