Browsing Bergen Open Research Archive by Author "Qu, Yi"
Now showing items 1-4 of 4
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Context dependent regulatory patterns of the androgen receptor and androgen receptor target genes
Olsen, Jan R; Azeem, Waqas; Hellem, Margrete R; Marvyin, Kristo; Hua, Yaping; Qu, Yi; Li, Lisha; Lin, Biaoyang; Ke, XI- S; Øyan, Anne Margrete; Kalland, Karl-Henning (Peer reviewed; Journal article, 2016-07-04)Background Expression of the androgen receptor (AR) is associated with androgen-dependent proliferation arrest and terminal differentiation of normal prostate epithelial cells. Additionally, activation of the AR is required ... -
Epithelial to Mesenchymal Transition of a Primary Prostate Cell Line with Switches of Cell Adhesion Modules but without Malignant Transformation
Ke, Xi-Song; Qu, Yi; Goldfinger, Naomi; Rostad, Kari; Hovland, Randi; Akslen, Lars A.; Rotter, Varda; Øyan, Anne Margrete; Kalland, Karl-Henning (Peer reviewed; Journal article, 2008-10-13)Background: Epithelial to mesenchymal transition (EMT) has been connected with cancer progression in vivo and the generation of more aggressive cancer cell lines in vitro. EMT has been induced in prostate cancer cell lines, ... -
Generation of a stepwise prostate carcinogenesis model. A study of epithelial to mesenchymal transition and malignant transformation of prostate primary epithelial cells
Qu, Yi (Doctoral thesis; Peer reviewed, 2013-05-29)Despite progress in recent years, prostate cancer continues to be one of the most prevalent causes of cancer-related mortality and morbidity in men in Western countries. A major clinical challenge of prostate cancer therapy ... -
Global profiling of histone and DNA methylation reveals epigenetic-based regulation of gene expression during epithelial to mesenchymal transition in prostate cells
Ke, Xi-Song; Qu, Yi; Cheng, Yang; Li, Wen-Cheng; Rotter, Varda; Øyan, Anne Margrete; Kalland, Karl-Henning (Peer reviewed; Journal article, 2010-11-25)Background: Previously we reported extensive gene expression reprogramming during epithelial to mesenchymal transition (EMT) of primary prostate cells. Here we investigated the hypothesis that specific histone and DNA ...