Browsing Bergen Open Research Archive by Author "Rødahl, Eyvind"

Now showing items 1-10 of 10

    • Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice 

      Svärd, Jessica; Røst, Therese Halvorsen; Sommervoll, Camilla Elise Nergård; Haugen, Christine; Gudbrandsen, Oddrun Anita; Christensen, Anne Elisabeth; Rødahl, Eyvind; Fernø, Johan; Dankel, Simon N; Sagen, Jørn V.; Mellgren, Gunnar (Peer reviewed; Journal article, 2019)
      Studies have implicated the extracellular matrix (ECM) of adipose tissue in insulin resistance. The proteoglycan decorin, a component of ECM, has been associated with glucose tolerance, but possible causal effects on ...

    • Corneal Vascularization Associated With a Novel PDGFRB Variant 

      Gladkauskas, Titas; Bruland, Ove; Safieh, Leen Abu; Edward, Deepak P.; Rødahl, Eyvind; Bredrup, Cecilie (Journal article; Peer reviewed, 2023)
      Purpose: The purpose of this study was to identify the genetic cause of aggressive corneal vascularization in otherwise healthy children in one family. Further, to study molecular consequences associated with the identified ...

    • Functional characterization of all-trans retinoic acid-induced differentiation factor (ATRAID) 

      Mehrasa, Roya; Cristea, Ileana; Bredrup, Cecilie; Rødahl, Eyvind; Bruland, Ove (Journal article; Peer reviewed, 2023)
      All-trans retinoic acid-induced differentiation (ATRAID) factor was first identified in HL60 cells. Several mRNA isoforms exist, but the respective proteins have not been fully characterized. In transfected cells expressing ...

    • K+ regulates relocation of Pellino-2 to the site of NLRP3 inflammasome activation in macrophages 

      Cristea, Ileana; Bruland, Ove; Rødahl, Eyvind; Bredrup, Cecilie (Journal article; Peer reviewed, 2021)
      Pellino proteins are E3 ubiquitin ligases involved in the innate immune system. Recently, Pellino-2 was reported to modulate the activation of the mouse Nlrp3 inflammasome. We examined the intracellular localization of ...

    • Molecular Biomarkers in Thyroid Eye Disease: A Literature Review 

      Ueland, Hans Olav; Neset, Mikael Thomassen; Methlie, Paal; Ueland, Grethe Åstrøm; Pakdel, Farzad; Rødahl, Eyvind (Journal article; Peer reviewed, 2023)
      Purpose: Thyroid eye disease (TED) is the most common extrathyroidal manifestation of Graves disease. Patients may be severely affected with eyelid retraction, exophthalmos, diplopia, pain, and threatened vision. ...

    • Novel inflammatory biomarkers in thyroid eye disease 

      Ueland, Hans Olav; Ueland, Grethe Åstrøm; Løvås, Kristian; Breivik, Lars Ertesvåg; Thrane, Alexander Stanley; Stokland, Ann-Elin Meling; Rødahl, Eyvind; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2022)
      Purpose: The aim of this study is to identify biochemical inflammatory markers predicting the presence or risk of developing thyroid eye disease (TED) in patients with Graves' disease (GD). Methods: Patients with GD ...

    • Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization 

      Cristea, Ileana; Bruland, Ove; Rødahl, Eyvind; Bredrup, Cecilie (Journal article; Peer reviewed, 2021)
      Pellino-2 is an E3 ubiquitin ligase that mediates intracellular signaling in innate immune pathways. Most studies of endogenous Pellino-2 have been performed in macrophages, but none in nonimmune cells. Using yeast two-hybrid ...

    • A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium–digital keloid dysplasia 

      Cristea, Ileana; Abarca, Hugo; Christensen, Anne Elisabeth; Trubnykova, Milana; Mehrasa, Roya; Peters, Dorien J. M.; Houge, Gunnar Douzgos; Hennekam, Raoul C. M.; Rødahl, Eyvind; Bruland, Ove; Bredrup, Cecilie (Journal article; Peer reviewed, 2023)
      Ocular pterygium–digital keloid dysplasia (OPDKD) is a rare hereditary disease characterized by corneal ingrowth of vascularized conjunctival tissue early in life. Later, patients develop keloids on fingers and toes but ...

    • Systemic Activation of the Kynurenine Pathway in Graves Disease With and Without Ophthalmopathy 

      Ueland, Hans Olav; Ulvik, Arve; Løvås, Kristian; Wolff, Anette Susanne Bøe; Breivik, Lars Ertesvåg; Stokland, Ann-Elin Meling; Rødahl, Eyvind; Nilsen, Roy Miodini; Husebye, Eystein Sverre; Ueland, Grethe Åstrøm (Journal article; Peer reviewed, 2023)
      Context Graves disease (GD) is one of the most common autoimmune disorders. Recent literature has shown an immune response involving several different inflammatory related proteins in these patients. Objective This ...

    • Temperature-dependent autoactivation associated with clinical variability of PDGFRB Asn666 substitutions 

      Bredrup, Cecilie; Cristea, Ileana; Safieh, Leen Abu; Di Maria, Emilio; Gjertsen, Bjørn Tore; Tveit, Kåre Steinar; Thu, Frode; Bull, Nils; Edward, Deepak P.; Hennekam, Raoul C.; Høvding, Gunnar Jr; Haugen, Olav H.; Houge, Gunnar Douzgos; Rødahl, Eyvind; Bruland, Ove (Journal article; Peer reviewed, 2021)
      Ocular pterygium-digital keloid dysplasia (OPDKD) presents in childhood with ingrowth of vascularized connective tissue on the cornea leading to severely reduced vision. Later the patients develop keloids on digits but are ...