Browsing Bergen Open Research Archive by Author "Reiten, Ingeborg Nerbø"
Now showing items 1-3 of 3
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A liposomal formulation of simvastatin and doxorubicin for improved cardioprotective and anti-cancer effect
Bjørnstad, Ronja; Reiten, Ingeborg Nerbø; Knudsen, Kaja Skålnes; Schjøtt, Jan Didrik; Herfindal, Lars (Journal article; Peer reviewed, 2022)Anthracyclines such as doxorubicin (Dox) are the preferred chemotherapeutics for several cancers. However, Dox-induced cardiotoxicity limits its therapeutic potential. Liposomal encapsulation of Dox has been used for ... -
A new software tool for computer assisted in vivo high-content analysis of transplanted fluorescent cells in intact zebrafish larvae
Førde, Jan-Lukas; Reiten, Ingeborg Nerbø; Fladmark, Kari Espolin; Kittang, Astrid Marta Olsnes; Herfindal, Lars (Journal article; Peer reviewed, 2022)Acute myeloid leukemia and myelodysplastic syndromes are cancers of the bone marrow with poor prognosis in frail and older patients. To investigate cancer pathophysiology and therapies, confocal imaging of fluorescent ... -
Zebrafish Larvae as a Model to Study Doxorubicin-Induced Cardiotoxicity
Reiten, Ingeborg Nerbø (Master thesis, 2020-06-30)Doxorubicin is one of the most versatile cytostatic drugs available and shows efficacy on most cancer forms. However, it also possesses the risk of cardiotoxicity that is hard to predict, can occur decades after treatment, ...