Browsing Bergen Open Research Archive by Author "Retterstøl, Kjetil"
Now showing items 1-11 of 11
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2.5-fold increased risk of recurrent acute myocardial infarction with familial hypercholesterolemia
Svendsen, Karianne; Krogh, Henriette Walaas; Igland, Jannicke; Tell, Grethe S.; Mundal, Liv J.; Holven, Kirsten Bjørklund; Bogsrud, Martin P.; Leren, Trond P.; Retterstøl, Kjetil (Journal article; Peer reviewed, 2021)Background and aims A first-time acute myocardial infarction (AMI) is a severe diagnosis that leads to initiation or intensification of lipid-lowering medication to prevent recurrent events. Individuals with familial ... -
Association of Familial Hypercholesterolemia and Statin Use With Risk of Dementia in Norway
Mundal, Liv; Igland, Jannicke; Svendsen, Karianne; Holven, Kirsten Bjørklund; Leren, Trond Paul; Retterstøl, Kjetil (Journal article; Peer reviewed, 2022)Importance Hypercholesterolemia, which is a cardiovascular risk factor, may also be associated with dementia risk. The benefit of statin treatment on dementia risk is controversial. Objective To determine whether ... -
Association of low-density lipoprotein cholesterol with risk of aortic valve stenosis in familial hypercholesterolemia
Mundal, Liv; Hovland, Anders; Igland, Jannicke; Veierød, Marit Bragelien; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Tell, Grethe S.; Leren, Trond Paul; Retterstøl, Kjetil (Peer reviewed; Journal article, 2019)Importance: Aortic valve stenosis (AS) is the most common valve disease. Elevated levels of low-density lipoprotein (LDL) cholesterol are a risk factor; however, lipid-lowering treatment seems not to prevent progression ... -
Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals
Hovland, Anders; Nestvold, Torunn Kristin; Bohov, Pavol; Trøseid, Marius; Aukrust, Pål; Berge, Rolf Kristian; Nielsen, Erik Waage; Retterstøl, Kjetil; Lappegård, Knut Tore (Peer reviewed; Journal article, 2017)Background: Obesity is a global pandemic leading to increased mortality and increased risk of cardiovascular disease. Bariatric surgery is an established treatment of obesity leading to weight loss and reduction of mortality. ... -
Economic evaluation of lipid lowering with PCSK9 inhibitors in patients with familial hypercholesterolemia: Methodological aspects
Wisløff, Torbjørn; Mundal, Liv; Retterstøl, Kjetil; Igland, Jannicke; Kristiansen, Ivar Sønbø (Peer reviewed; Journal article, 2019)Background and aims: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have proved to reduce low density lipoprotein cholesterol levels in numerous clinical trials. In two large clinical trials, PCSK9 inhibitor ... -
Impact of age on excess risk of coronary heart disease in patients with familial hypercholesterolaemia
Mundal, Liv; Igland, Jannicke; Veierød, Marit Bragelien; Holven, Kirsten Bjørklund; Ose, Leiv; Selmer, Randi; Wisløff, Torbjørn; Kristiansen, Ivar Sønbø; Tell, Grethe S.; Leren, Trond Paul; Retterstøl, Kjetil (Peer reviewed; Journal article, 2018)Objective: The primary objective was to study the risk of acute myocardial infarction (AMI) and coronary heart disease (CHD) in patients with familial hypercholesterolaemia (FH) and compare with the risk in the general ... -
Individuals with familial hypercholesterolemia have excess risk of eating disorders - a prospectively matched cohort study
Urke, Eli Bjørnøy; Igland, Jannicke; Mundal, Liv; Holven, Kirsten Bjørklund; Retterstøl, Kjetil; Svendsen, Karianne (Journal article; Peer reviewed, 2022) -
Lower risk of smoking-related cancer in individuals with familial hypercholesterolemia compared with controls: a prospective matched cohort study
Krogh, Henriette Walaas; Svendsen, Karianne; Igland, Jannicke; Mundal, Liv; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Leren, Trond Paul; Retterstøl, Kjetil (Peer reviewed; Journal article, 2019-12-17)According to guidelines, individuals with familial hypercholesterolemia (FH) shall receive lifestyle intervention and intensive lipid-lowering treatment from early in life to reduce the risk of coronary heart disease. Our ... -
Risk of Ischemic Stroke and Total Cerebrovascular Disease in Familial Hypercholesterolemia.
Hovland, Anders; Mundal, Liv; Igland, Jannicke; Veierød, Marit Bragelien; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Tell, Grethe S.; Leren, Trond Paul; Retterstøl, Kjetil (Peer reviewed; Journal article, 2019-01)Background and Purpose—Familial hypercholesterolemia (FH) is a common autosomal dominant disease leading to increased level of serum LDL (low-density lipoprotein) cholesterol and risk of coronary heart disease. Whether FH ... -
Risk of stroke in genetically verified familial hypercholesterolemia: A prospective matched cohort study
Svendsen, Karianne; Olsen, Thomas; Vinknes, Kathrine Jørgensen; Mundal, Liv; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Leren, Trond Paul; Igland, Jannicke; Retterstøl, Kjetil (Journal article; Peer reviewed, 2022)Background and aims Individuals with familial hypercholesterolemia (FH), causing severely elevated LDL-C, are expected to have a higher risk of ischemic stroke. The risk of hemorrhagic stroke and impact of statin use are, ... -
The risk of various types of cardiovascular diseases in mutation positive familial hypercholesterolemia; a review
Hovland, Anders; Mundal, Liv; Veierød, Marit Bragelien; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Tell, Grethe Seppola; Leren, Trond Paul; Retterstøl, Kjetil (Journal article; Peer reviewed, 2022)Familial hypercholesterolemia (FH) is a common, inherited disease characterized by high levels of low-density lipoprotein Cholesterol (LDL-C) from birth. Any diseases associated with increased LDL-C levels including ...