• Microfluidics for studying metastatic patterns of lung cancer 

      Ruzycka, Monika; Cimpan, Mihaela Roxana; Rios Mondragon, Ivan; Grudzinski, Ireneusz (Peer reviewed; Journal article, 2019-05-27)
      The incidence of lung cancer continues to rise worldwide. Because the aggressive metastasis of lung cancer cells is the major drawback of successful therapies, the crucial challenge of modern nanomedicine is to develop ...
    • Phosphorylation at serine 31 targets tyrosine hydroxylase tovesicles for transport along microtubules 

      Jorge Finnigan, Ana; Kleppe, Rune; K C, Kunwar Jung; Ying, Ming; Marie, Michael Bruno Eric; Rios Mondragon, Ivan; Salvatore, Michael F; Saraste, Jaakko; Martinez, Aurora (Peer reviewed; Journal article, 2017)
      Tyrosine hydroxylase (TH) catalyzes the conversion of L-tyrosine into L-DOPA, which is the rate-limiting step in the synthesis of catecholamines, such as dopamine, in dopaminergergic neurons. Low dopamine levels and death ...