Browsing Bergen Open Research Archive by Author "Roalsø, Marcus Thomas Thor"
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Early Diagnosis of Pancreatic Cancer: Clinical Premonitions, Timely Precursor Detection and Increased Curative-Intent Surgery
Søreide, Kjetil; Ismail, Warsan; Roalsø, Marcus Thomas Thor; Ghotbi, Jacob; Zaharia, Claudia (Journal article; Peer reviewed, 2023)Background: The overall poor prognosis in pancreatic cancer is related to late clinical detection. Early diagnosis remains a considerable challenge in pancreatic cancer. Unfortunately, the onset of clinical symptoms in ... -
Emerging Role of Epigenetic Alterations as Biomarkers and Novel Targets for Treatments in Pancreatic Ductal Adenocarcinoma
Roalsø, Marcus Thomas Thor; Hald, Øyvind; Alexeeva, Marina; Søreide, Kjetil (Journal article; Peer reviewed, 2022)Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with limited treatment options. Emerging evidence shows that epigenetic alterations are present in PDAC. The changes are potentially reversible and therefore ... -
En ung mann med akutte magesmerter og anemi
Roalsø, Marcus Thomas Thor; Karlsen, Lars Normann; Buchmann, Petr; Haukås, Einar; Søreide, Kjetil (Journal article; Peer reviewed, 2023) -
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis
Søreide, Kjetil; Roalsø, Marcus Thomas Thor; Aunan, Jan Rune (Journal article; Peer reviewed, 2020)Purpose: Pancreatic cancer is one of the most lethal of solid tumors and is associated with aggressive cancer biology. The purpose is to review the role of trypsin and effect on molecular and cellular processes potentially ... -
Refined TNM-staging for pancreatic adenocarcinoma – Real progress or much ado about nothing?
Roalsø, Marcus Thomas Thor; Aunan, Jan Rune; Søreide, Kjetil (Journal article; Peer reviewed, 2020-02-20)In order to provide optimal cancer care and prognostication, it is necessary to stage the disease. The 8th edition of the TNM-staging for exocrine pancreatic ductal adenocarcinoma (PDAC) system has refined size-based ...