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Blar i Bergen Open Research Archive på forfatter "Søiland, Håvard"

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    • The Active Tamoxifen Metabolite Endoxifen (4OHNDtam) Strongly Down-Regulates Cytokeratin 6 (CK6) in MCF-7 Breast Cancer Cells 

      Helland, Thomas; Gjerde, Jennifer; Dankel, Simon N.; Fenne, Ingvild Sveinsgjerd; Skartveit, Linn; Drangevåg, Andreas; Bozickovic, Olivera; Flågeng, Marianne Hauglid; Søiland, Håvard; Mellgren, Gunnar; Lien, Ernst Asbjørn (Peer reviewed; Journal article, 2015-04-13)
      Introduction: Tamoxifen is an anti-estrogen drug used in treatment of Estrogen Receptor (ER) positive breast cancer. Effects and side effects of tamoxifen is the sumof tamoxifen and all itsmetabolites. 4-Hydroxytamoxifen ...
    • Ekspressiv skriving som egenterapeutisk verktøy ett år etter brystkreftdiagnosen - resultater fra en beskrivende pilotstudie 

      Gripsrud, Birgitta Haga; Søiland, Håvard; Lode, Kirsten (Peer reviewed; Journal article, 2014)
      The article presents findings from a pilot study on expressive writing, a therapeutic method undescribed in a Norwegian scientific context. Objective: 1. Gain qualitative data on breast cancer women’s experiences with ...
    • Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients - a randomized trial 

      Lende, Tone Hoel; Austdal, Marie; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Kvaløy, Jan Terje; Akslen, Lars A.; Søiland, Håvard; Janssen, Emiel; Baak, Jan P.A. (Peer reviewed; Journal article, 2019-11-08)
      Background: Conflicting results have been reported on the influence of carbohydrates in breast cancer. Objective: To determine the influence of pre-operative per-oral carbohydrate load on proliferation in breast tumors. ...
    • Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study 

      Lende, Tone Hoel; Austdal, Marie; Bathen, Tone Frost; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Egeland, Nina Gran; Lunde, Siri; Akslen, Lars A.; Jonsdottir, Kristin; Janssen, Emiel; Søiland, Håvard; Baak, Jan P.A. (Peer reviewed; Journal article, 2019-12-04)
      Background: The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative ...
    • Our genes, our selves: hereditary breast cancer and biological citizenship in Norway 

      Solbrække, Kari Nyheim; Søiland, Håvard; Lode, Kirsten; Gripsrud, Birgitta Haga (Peer reviewed; Journal article, 2017-03)
      In this paper we explore the rise of ‘the breast cancer gene’ as a field of medical, cultural and personal knowledge. We address its significance in the Norwegian public health care system in relation to so-called biological ...
    • The role of microRNAs as predictors of response to tamoxifen treatment in breast cancer patients 

      Egeland, Nina; Lunde, Siri; Jonsdottir, Kristin; Lende, Tone Hoel; Cronin-Fenton, Deirdre P.; Gilje, Bjørnar; Janssen, Emilius Adrianus Maria; Søiland, Håvard (Peer reviewed; Journal article, 2015-10-14)
      Endocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast cancer. However, resistance to endocrine therapy leads to breast cancer relapse. The recent extension of adjuvant tamoxifen ...
    • Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients 

      Helland, Thomas; Henne, Nina; Bifulco, Ersilia; Naume, Bjørn; Borgen, Elin; Kristensen, Vessela N.; Kvaløy, Jan Terje; Lash, Timothy L; Grenaker, Grethe Irene; van Schaik, RHN; Janssen, Emiel; Hustad, Simon Steinar; Lien, Ernst Asbjørn; Mellgren, Gunnar; Søiland, Håvard (Peer reviewed; Journal article, 2017-11-28)
      Background: Controversies exist as to whether the genetic polymorphisms of the enzymes responsible for the metabolism of tamoxifen can predict breast cancer outcome in patients using adjuvant tamoxifen. Direct measurement ...

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