Blar i Bergen Open Research Archive på forfatter "Søreide, Kjetil"
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Anastomotic leak after surgery for colon cancer and effect on long‐term survival
Stormark, Kjartan; Krarup, Peter-Martin; Sjövall, Annika; Søreide, Kjetil; Kvaløy, Jan Terje; Nordholm-Carstensen, Andreas; Nedrebø, Bjørn Steinar Olden; Kørner, Hartwig (Journal article; Peer reviewed, 2020)Aim An anastomotic leak after surgery for colon cancer is a recognized complication but how it may adversely affect long‐term survival is less clear because data are scarce. The aim of the study was to investigate the ... -
Assessment of clinically related outcomes and biomarker analysis for translational integration in colorectal cancer (ACROBATICC): study protocol for a population-based, consecutive cohort of surgically treated colorectal cancers and resected colorectal liver metastasis
Søreide, Kjetil; Watson, Martin M; Lea, Dordi; Nordgård, Oddmund; Søreide, Jon Arne; Hagland, Hanne R (Peer reviewed; Journal article, 2016-06-29)Background: More accurate predictive and prognostic biomarkers for patients with colorectal cancer (CRC) primaries or colorectal liver metastasis (CLM) are needed. Outside clinical trials, the translational integration of ... -
Assessment of retention force and bone apposition in two differently coated femoral stems after 6 months of loading in a goat model
Harboe, Knut; Gjerdet, Nils Roar; Sudmann, Einar; Indrekvam, Kari; Søreide, Kjetil (Peer reviewed; Journal article, 2014-08-16)Background: Since the introduction of uncemented hip implants, there has been a search for the best surface coating to enhance bone apposition in order to improve retention. The surface coating of the different stems varies ... -
Benchmarking of aggregated length of stay after open and laparoscopic surgery for cancers of the digestive system
Lassen, Kristoffer; Nymo, Linn Såve; Olsen, Frank; Søreide, Kjetil (Peer reviewed; Journal article, 2018-08-01)Background: Length of hospital stay (LOS) may serve as a surrogate measure of healthcare quality and resource use, particularly when transfers of care and readmissions are accounted for. This study aimed to benchmark true ... -
The biology of aging and cancer: A brief overview of shared and divergent molecular hallmarks
Aunan, Jan Rune; Cho, William C; Søreide, Kjetil (Peer reviewed; Journal article, 2017-10)Aging is the inevitable time-dependent decline in physiological organ function and is a major risk factor for cancer development. Due to advances in health care, hygiene control and food availability, life expectancy is ... -
Can bone apposition predict the retention force of a femoral stem? An experimental weight-bearing hip-implant model in goats
Harboe, Knut; Ellingsen, Christian Lycke; Sudmann, Einar; Gjerdet, Nils Roar; Søreide, Kjetil; Indrekvam, Kari (Peer reviewed; Journal article, 2015-04-28)Background: The increasing incidence of prosthesis revision surgery in the Western world has led to an increased focus on the capacity for stem removal. We previously reported on a femoral stem implanted in goats with an ... -
Cancer epigenetics in solid organ tumours: A primer for surgical oncologists
Drake, Thomas M.; Søreide, Kjetil (Peer reviewed; Journal article, 2019-05)Cancer is initiated through both genetic and epigenetic alterations. The end-effect of such changes to the DNA machinery is a set of uncontrolled mechanisms of cell division, invasion and, eventually, metastasis. Epigenetic ... -
Cellular metabolism in colorectal carcinogenesis: Influence of lifestyle, gut microbiome and metabolic pathways
Søreide, Kjetil; Hagland, Hanne (Peer reviewed; Journal article, 2014-03-12)The interconnectivity between diet, gut microbiota and cell molecular responses is well known; however, only recently has technology allowed the identification of strains of microorganisms harbored in the gastrointestinal ... -
Centralizing a national pancreatoduodenectomy service: striking the right balance
Nymo, Linn Såve; Kleive, Dyre; Waardal, Kim; Bringeland, Erling Audun; Søreide, Jon Arne; Labori, Knut Jørgen; Mortensen, Kim Erlend; Søreide, Kjetil; Lassen, Kristoffer (Journal article; Peer reviewed, 2020)Background Centralization of pancreatic surgery is currently called for owing to superior outcomes in higher-volume centres. Conversely, organizational and patient concerns speak for a moderation in centralization. Consensus ... -
Changing from a two-tiered to a one-tiered trauma team activation protocol: a before–after observational cohort study investigating the clinical impact of undertriage
Thorsen, Kenneth; Narvestad, Jon; Tjosevik, Kjell Egil; Larsen, Johannes Wiik; Søreide, Kjetil (Journal article; Peer reviewed, 2021)Background: The aim of this study was to compare the effect of the change in TTA protocol from a two-tier to one-tier, with focus on undertriage and mortality. Material and methods: A before–after observational cohort ... -
Characteristics and fate of patients with rectal cancer not entering a curative-intent treatment pathway: A complete nationwide registry cohort of 3,304 patients
Kørner, Hartwig; Guren, Marianne; Larsen, Inger Kristin; Haugen, Dagny Renata Faksvåg; Søreide, Kjetil; Kørner, Leif Roland; Søreide, Jon Arne (Journal article; Peer reviewed, 2022)Background: Treatment options for advanced and metastatic rectal cancer have increased during the past decades. However, a considerable proportion of the patients are not eligible for curative treatment, and data on this ... -
Clinical Management of Pancreatic Premalignant Lesions
Søreide, Kjetil; Marchegiani, Giovanni (Journal article; Peer reviewed, 2022) -
Clinical patterns of presentation and attenuated inflammatory response in octo- and nonagenarians with perforated gastroduodenal ulcers
Søreide, Kjetil; Thorsen, Kenneth; Søreide, Jon Arne (Peer reviewed; Journal article, 2016-08)Background. Perforated gastrodudenal ulcer (PGDU) is an operative emergency with high mortality rates. The growing elderly populationincreasingly presents with need for geriatric acute operative care. Current knowledge of ... -
Collecting core data in severely injured patients using a consensus trauma template: an international multicentre study
Ringdal, Kjetil Gorseth; Lossius, Hans Morten; Jones, Mary J.; Lauritsen, Jens M.; Coats, Timothy J.; Palmer, Cameron S.; Lefering, Rolf; Bartolomeo, Stefano Di; Dries, David J.; Søreide, Kjetil (Peer reviewed; Journal article, 2011-10-12)Introduction: No worldwide, standardised definitions exist for documenting, reporting and comparing data from severely injured trauma patients. This study evaluated the feasibility of collecting the data variables of the ... -
Comparison of CpG Island Methylator Phenotype (CIMP) Frequency in Colon Cancer Using Different Probe- and Gene-Specific Scoring Alternatives on Recommended Multi-Gene Panels
Berg, Marianne; Hagland, Hanne; Søreide, Kjetil (Peer reviewed; Journal article, 2014-01-21)Background: In colorectal cancer a distinct subgroup of tumours demonstrate the CpG island methylator phenotype (CIMP). However, a consensus of how to score CIMP is not reached, and variation in definition may influence ... -
Comparison of Performance Score for Female and Male Residents in General Surgery Doing Supervised Real-Life Laparoscopic Appendectomy: Is There a Norse Shield-Maiden Effect?
Skjold-Ødegaard, Benedicte; Ersdal, Hege Langli; Assmus, Jörg; Søreide, Kjetil (Journal article; Peer reviewed, 2021)Background Gender bias may represent a threat to resident assessment during surgical training, and there have been concerns that women might be disadvantaged. There is a lack of studies investigating gender differences ... -
Deciphering the inflection points to achieve proficiency for each procedure step during training in laparoscopic appendicectomy
Skjold-Ødegaard, B.; Hamid, S.; Lindeman, Robbert-Jan; Ersdal, H.L.; Søreide, Kjetil (Journal article; Peer reviewed, 2021)Background Laparoscopic appendicectomy is a common procedure early in surgical training. A minimum number is usually required for certification in general surgery. However, data on proficiency are scarce. This study aimed ... -
Determining universal processes related to best outcome in emergency abdominal surgery: A multicentre, international, prospective cohort study
Bhangu, Aneel; Fitzgerald, J. Edward; Fergusson, Stuart; Khatri, Chetan; Holmer, Hampus; Søreide, Kjetil; Harrison, Ewen M. (Peer reviewed; Journal article, 2014-10-29)Introduction: Emergency abdominal surgery outcomes represent an internationally important marker of healthcare quality and capacity. In this study, a novel approach to investigating global surgical outcomes is proposed, ... -
Development and clinical implementation of a structured, simulation-based training programme in laparoscopic appendectomy: Description, validation and evaluation
Skjold-Ødegaard, Benedicte; Ersdal, Hege Langli; Assmus, Jörg; Nedrebø, Bjørn Steinar Olden; Sjo, Ole; Søreide, Kjetil (Journal article; Peer reviewed, 2021)Background: Laparoscopic appendectomy is a common procedure in general surgery but is likely underused in structured and real-life teaching. This study describes the development, validation and evaluation of implementing ... -
The diagnostic differentiation challenge in acute appendicitis: How to distinguish between uncomplicated and complicated appendicitis in adults
Skjold-Ødegaard, Benedicte; Søreide, Kjetil (Journal article; Peer reviewed, 2022-07-15)Background: How to best define, diagnose and differentiate uncomplicated from complicated acute appendicitis remains debated. Hence, the aim of this review was to present an overview of the current knowledge and emerging ...