Browsing Bergen Open Research Archive by Author "Sakkestad, Sunniva Todnem"
Now showing items 1-3 of 3
-
Experimental Infection of Human Volunteers with the Heat-Stable Enterotoxin-Producing Enterotoxigenic Escherichia coli Strain TW11681
Sakkestad, Sunniva Todnem; Steinsland, Hans; Skrede, Steinar; Kleppa, Elisabeth; Lillebø, Kristine; Sævik, Marianne; Søyland, Hanne; Heien, Astrid Rykkje; Tellevik, Marit Gjerde; Barry, Eileen M.; Sommerfelt, Halvor; Hanevik, Kurt (Peer reviewed; Journal article, 2019-06-22)Infection with enterotoxigenic Escherichia coli (ETEC) producing the heat-stable enterotoxin (ST) is one of the most important causes of childhood diarrhoea in low- and middle-income countries. Here, we undertook a controlled ... -
A New Human Challenge Model for Testing Heat-Stable Toxin-Based Vaccine Candidates for Enterotoxigenic Escherichia Coli Diarrhea - Dose Optimization, Clinical Outcomes, and CD4+ T Cell Responses
Sakkestad, Sunniva Todnem; Steinsland, Hans; Skrede, Steinar; Lillebø, Kristine; Skutlaberg, Dag Harald; Guttormsen, Anne Berit; Zavialov, Anton; Paavilainen, Sari; Søyland, Hanne; Sævik, Marianne; Rykkje Heien, Astrid; Gjerde Tellevik, Marit; Barry, Eileen; Langeland, Nina; Sommerfelt, Halvor; Hanevik, Kurt (Peer reviewed; Journal article, 2019-10-30)Enterotoxigenic Escherichia coli (ETEC) are a common cause of diarrheal illness in young children and travelers. There is yet no licensed broadly protective vaccine against ETEC. One promising vaccine development strategy ... -
Proliferation of enterotoxigenic Escherichia coli strain TW11681 in stools of experimentally infected human volunteers
Vedøy, Oda Barth; Hanevik, Kurt; Sakkestad, Sunniva Todnem; Sommerfelt, Halvor; Steinsland, Hans (Peer reviewed; Journal article, 2018-10-16)Background: As part of the efort to develop an enterotoxigenic Escherichia coli (ETEC) human challenge model for testing new heat-stable toxin (ST)-based vaccine candidates, a controlled human infection model study based ...