Browsing Bergen Open Research Archive by Author "Sangnes, Dag André"
Now showing items 1-11 of 11
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Clinical response to fecal microbiota transplantation in patients with diarrhea-predominant irritable bowel syndrome is associated with normalization of fecal microbiota composition and short-chain fatty acid levels
Mazzawi, Tarek; Hausken, Trygve; Hov, Johannes Espolin Roksund; Valeur, Jørgen; Sangnes, Dag André; El-Salhy, Magdy; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Lied, Gülen Arslan (Peer reviewed; Journal article, 2019)Objectives: Irritable bowel syndrome (IBS) may be associated with disturbances in gut microbiota composition and functions. We recently performed a study of fecal microbiota transplantation (FMT) in diarrhea-predominant ... -
Comparing radiopaque markers and 13C-labelled breath test in diabetic gastroparesis diagnostics
Sangnes, Dag André; Softeland, Eirik; Teigland, Tonje; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2019)Purpose: Determining gastric emptying is mandatory in the diagnosis of diabetic gastroparesis. Several methods of investigation exist, but none has proven reliable, inexpensive and accessible. In this study, we aimed to ... -
Diabetic diarrhoea: a study on gastrointestinal motility, pH levels and autonomic function
Sangnes, Dag André; Dimcevski, Georg; Frey, Jakub; Søfteland, Eirik Wigtil (Journal article; Peer reviewed, 2021)Background Chronic diarrhoea is a common, but poorly investigated diabetes complication. Autonomic neuropathy is a leading pathophysiological theory founded on old, small studies. Studies of gastrointestinal motility and ... -
Diagnostic Accuracy of Transabdominal Ultrasound and Computed Tomography in Chronic Pancreatitis: A Head-to-Head Comparison
Nordaas, Ingrid Kvåle; Engjom, Trond; Gilja, Odd Helge; Havre, Roald Flesland; Sangnes, Dag André; Haldorsen, Ingfrid S.; Dimcevski, Georg Gjorgji (Journal article; Peer reviewed, 2021)Purpose Computed tomography (CT) is the most used imaging modality for diagnosing chronic pancreatitis (CP), but advances in transabdominal ultrasound (US) technology have given US a position as a viable alternative. We ... -
Diagnostic accuracy of transabdominal ultrasound in chronic pancreatitis
Engjom, Trond; Sangnes, Dag André; Havre, Roald Flesland; Erchinger, Friedemann Georg; Pham, Khanh Do-Cong; Haldorsen, Ingfrid S.; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2017-04)The performance of transabdominal ultrasound (US) in chronic pancreatitis (CP) following the advances in US technology made during recent decades has not been explored. Our aim in this prospective study was to evaluate the ... -
Gastroparesis Symptoms Associated with Intestinal Hypomotility: An Explorative Study Using Wireless Motility Capsule
Bekkelund, Mattis; Sangnes, Dag André; Søfteland, Eirik Wigtil; Aabakken, Lars; Biermann, Martin; Steinsvik, Elisabeth K.; Hausken, Trygve; Dimcevski, Georg; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2021)Objective: Gastric emptying measurements are mandatory in gastroparesis diagnostics, but the association between delayed emptying and symptoms is questionable. It is imperative to find biomarkers better correlated to symptom ... -
The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
Mazzawi, Tarek; Lied, Gülen Arslan; Sangnes, Dag André; El-Salhy, Magdy; Hov, Johannes Espolin Roksund; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Hausken, Trygve (Peer reviewed; Journal article, 2018-11-14)Background: Gut microbiota alterations are important in irritable bowel syndrome (IBS). The aim was to investigate the effect of fecal microbiota transplantation (FMT) on gut microbiota and the symptoms in patients with ... -
Pancreatic exocrine insufficiency in diabetes is associated with autonomic dysfunction
Sangnes, Dag André; Bergmann, Elisabeth Sandvik; Moss, Rose Marie; Engjom, Trond; Søfteland, Eirik Wigtil (Journal article; Peer reviewed, 2021)Objectives: Pancreatic exocrine insufficiency (PEI) is prevalent in diabetes. Pathophysiological theories imply autoimmune destruction, lack of trophic effects of insulin or impaired neuronal stimulation, but the relationship ... -
Pathophysiology of idiopathic gastroparesis and implications for therapy
Bekkelund, Mattis; Sangnes, Dag André; Hatlebakk, Jan Gunnar; Aabakken, Lars (Peer reviewed; Journal article, 2019)Objectives: Idiopathic gastroparesis is a gastric motility disorder characterized by chronic upper gastrointestinal symptoms and delayed gastric emptying without an identifiable underlying condition. This review summarizes ... -
Prolonged intestinal transit and diarrhea in patients with an activating GUCY2C mutation
Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Gilja, Odd Helge; Tronstad, Rune Rose; Sangnes, Dag André; Nortvedt, Ragnar; Hausken, Trygve; Dimcevski, Georg Gjorgji; Fiskerstrand, Torunn; Nylund, Kim (Peer reviewed; Journal article, 2017)Introduction: Increased intestinal hydration by activation of the epithelial enzyme linked receptor guanylate cyclase C (GC-C) is a pharmacological principle for treating constipation. Activating mutations in the GUCY2C ... -
Wireless motility capsule compared with scintigraphy in the assessment of diabetic gastroparesis
Sangnes, Dag André; Søfteland, Eirik; Bekkelund, Mattis; Frey, Jakub; Biermann, Martin; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2019-12-30)Background: Gastroparesis is a potentially severe late complication of diabetes mellitus. Today, delayed gastric emptying (GE) is mandatory for establishing the diagnosis. In this study, we compared wireless motility capsule ...