• The Culture Dish Surface Influences the Phenotype and Cytokine Production of Human Monocyte-Derived Dendritic Cells 

      Sauter, Alexander; Yi, Dag Heiro; Li, Yayan; Roersma, Sabine; Appel, Silke (Peer reviewed; Journal article, 2019-10-02)
      Monocyte-derived dendritic cells (moDC) are an important scientific and clinical source of functional dendritic cells (DC). However, the optimization of the generation process has to date mainly been limited to the variation ...
    • Effective polyethylene glycol passivation for the inhibition of surface interactions of peripheral blood mononuclear cells and platelets 

      Sauter, Alexander; Richter, Gunther; Micoulet, Alexandre; Martinez, Aurora; Spatz, Joachim P.; Appel, Silke (Peer reviewed; Journal article, 2013-06-20)
      The inhibition of unspecific adhesion of human white blood cells is a prerequisite for applications requiring the control of defined surface interactions. In this study, a passivation agent based on polyethylene glycol ...
    • High throughput toxicity screening and intracellular detection of nanomaterials 

      Collins, Andrew Richard; Balasubramanyam, Annangi; Rubio, Laura; Marcos, Ricard; Dorn, Marco; Merker, Carolin; Estrela-Lopis, Irina; Cimpan, Mihaela Roxana; Ibrahim, Mohamed; Cimpan, Emil; Ostermann, Melanie; Sauter, Alexander; El Yamani, Naouale; Shaposhnikov, Sergey; Chevillard, Sylvie; Paget, Vincent; Grall, Romain; Delic, Jozo; Goñi- de-Cerio, Felipe; Suarez-Merino, Blanca; Fessard, Valérie; Hogeveen, Kevin N; Fjellsbø, Lise Maria; Runden Pran, Elise; Brzicova, Tana; Topinka, Jan; João Silva, Maria; Leite, PE; Ribeiro, AR; Granjeiro, JM; Grafström, Roland; Prina-Mello, Adriele; Dusinska, Maria (Peer reviewed; Journal article, 2017-01)
      With the growing numbers of nanomaterials (NMs), there is a great demand for rapid and reliable ways of testing NM safety—preferably using in vitro approaches, to avoid the ethical dilemmas associated with animal research. ...
    • Label-free impedance flow cytometry for nanotoxicity screening 

      Ostermann, Melanie; Sauter, Alexander; Xue, Ying; Birkeland, Eivind Salmorin; Schoelermann, Julia; Holst, Bodil; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2020)
      The development of reliable and cost-efficient methods to assess the toxicity of nanomaterials (NMs) is critical for the proper identification of their impact on human health and for ensuring a safe progress of nanotechnology. ...