• Adverse childhood experiences and asthma: trajectories in a national cohort 

      Pape, Kathrine; Cowell, Whitney; Sejbaek, Camilla Sandal; Andersson, Niklas Worm; Svanes, Cecilie; Kolstad, Henrik A.; Liu, Xiaoqin; Hougaard, Karin Sørig; Wright, Rosalind J.; Schlünssen, Vivi (Journal article; Peer reviewed, 2021)
      Objective Research has linked early adverse childhood experiences (ACEs) with asthma development; however, existing studies have generally relied on parent report of exposure and outcome. We aimed to examine the association ...
    • Agreement in reporting of asthma by parents or offspring - the RHINESSA generation study 

      Kuiper, Ingrid Nordeide; Svanes, Cecilie; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali C.; Holm, Mathias; Janson, Christer; Jõgi, Rain; Malinovschi, Andrei; Matheson, Melanie; Moratalla, Jesús Martínez; Gomez Real, Francisco; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Timm, Signe; Johannessen, Ane (Peer reviewed; Journal article, 2018-07-27)
      Background: Self-report questionnaires are commonly used in epidemiology, but may be susceptible to misclassification, especially if answers are given on behalf of others, e.g. children or parents. The aim was to determine ...
    • Ascaris exposure and its association with lung function, asthma, and DNA methylation in Northern Europe 

      Jögi, Nils Oskar; Kitaba, Negusse; Storaas, Torgeir; Schlünssen, Vivi; Triebner, Kai Philipp; Holloway, John W; Horsnell, William G.C.; Svanes, Cecilie; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2022)
      Background Ascaris infections, with a worldwide prevalence above 10%, can cause respiratory pathology. However, long-term effects on lung function in humans are largely unknown. Objective We investigated the associations ...
    • Being overweight in childhood, puberty, or early adulthood: Changing asthma risk in the next generation? 

      Johannessen, Ane; Lønnebotn, Marianne; Calciano, Lucia; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali; Franklin, Karl A.; Gíslason, Þórarinn; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Jõgi, Rain; Kim, Jeong-Lim; Kirkeleit, Jorunn; Lodge, Caroline; Malinovschi, Andrei; Martinez-Moratalla, Jesus; Nilsen, Roy Miodini; Pereira-Vega, Antonio; Gomez Real, Francisco; Schlünssen, Vivi; Accordini, Simone; Svanes, Cecilie (Peer reviewed; Journal article, 2020-03)
      Background Overweight status and asthma have increased during the last decades. Being overweight is a known risk factor for asthma, but it is not known whether it might also increase asthma risk in the next generation. ...
    • Body silhouettes as a tool to reflect obesity in the past 

      Lønnebotn, Marianne; Svanes, Cecilie; Igland, Jannicke; Franklin, Karl A.; Accordini, Simone; Benediktsdóttir, Bryndís; Bentohuami, Hayat; Blanco, José Antonio Gullón; Bono, Roberto; Corsico, Angelo; Demoly, Pascal; Dharmage, Shyamali; Dorado Arenas, Sandra; Garcia, Judith; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Leynaert, Bénédicte; Martinez-Moratalla, Jesús; Nowak, Dennis; Pin, Isabelle; Raherison-Semjen, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Dratva, Julia; Gomez Real, Francisco (Peer reviewed; Journal article, 2018-04-25)
      Life course data on obesity may enrich the quality of epidemiologic studies analysing health consequences of obesity. However, achieving such data may require substantial resources. We investigated the use of body silhouettes ...
    • Breathlessness across generations: results from the RHINESSA generation study 

      Ekström, Magnus; Johannessen, Ane; Abramson, Michael J.; Benediktsdóttir, Bryndís; Franklin, Karl A.; Gislason, Thorarinn; Real, Francisco Gomez; Holm, Mathias; Janson, Christer; Jogi, Rain; Lowe, Adrian J.; Malinovschi, Andrei; Martínez-Moratalla, Jesús; Oudin, Anna; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie (Journal article; Peer reviewed, 2022)
      Background Breathlessness is a major cause of suffering and disability globally. The symptom relates to multiple factors including asthma and lung function, which are influenced by hereditary factors. No study has evaluated ...
    • Cohort profile: the multigeneration Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) cohort 

      Svanes, Cecilie; Johannessen, Ane; Bertelsen, Randi Jacobsen; Dharmage, Shyamali; Benediktsdottir, Bryndis; Bråbäck, Lennart; Gislason, Thorarinn; Holm, Mathias; Jögi, Oskar; Lodge, Caroline J; Malinovschi, Andrei; Martinez-Moratalla, Jesus; Oudin, Anna; Sánchez-Ramos, José Luis; Timm, Signe; Janson, Christer; Real, Francisco Gomez; Schlünssen, Vivi (Journal article; Peer reviewed, 2022)
      Purpose The Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) cohort was established to (1) investigate how exposures before conception and in previous generations influence health and disease, ...
    • Dampness and mold at home and at work and onset of insomnia symptoms, snoring and excessive daytime sleepiness 

      Wang, Juan; Janson, Christer; Lindberg, Eva; Holm, Mathias; Gislason, Thorarinn; Benediktsdóttir, Bryndís; Johannessen, Ane; Schlünssen, Vivi; Jõgi, Rain; Franklin, Karl A.; Norbäck, Dan (Journal article; Peer reviewed, 2020)
      Aim To investigate whether exposure to dampness and mold at home and at work induce sleep disturbances and daytime sleepiness among adults. Materials and methods Associations between onset of sleep disturbances and ...
    • Describing the status of reproductive ageing simply and precisely: A reproductive ageing score based on three questions and validated with hormone levels 

      Triebner, Kai; Johannessen, Ane; Svanes, Cecilie; Leynaert, Bénédicte; Benediktsdóttir, Bryndís; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Lindberg, Eva; Moratalla, Jesús Martínez; Agirre, Nerea Muniozguren; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Hustad, Steinar; Rodríguez, Francisco J.; Gomez Real, Francisco (Journal article; Peer reviewed, 2020)
      Objective Most women live to experience menopause and will spend 4–8 years transitioning from fertile age to full menstrual stop. Biologically, reproductive ageing is a continuous process, but by convention, it is defined ...
    • Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS) 

      Triebner, Kai; Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndís; Bifulco, Ersilia; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Garcia-Aymerich, Judith; Gullón Blanco, José Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Debbie; Jõgi, Rain; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie; Hustad, Simon Steinar; Leynaert, Bénédicte; Gomez Real, Francisco (Peer reviewed; Journal article, 2019)
      Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The ...
    • The Exposome Approach in Allergies and Lung Diseases: Is It Time to Define a Preconception Exposome? 

      López Cervantes, Juan Pablo; Lønnebotn, Marianne; Jögi, Nils Oskar; Calciano, Lucia; Kuiper, Ingrid Nordeide; Darby, Matthew G; Dharmage, Shyamali Chandrika; Real, Francisco Gomez; Hammer, Barbara; Bertelsen, Randi Jacobsen; Johannessen, Ane; Würtz, Anne Mette Lund; Knudsen, Gerd Toril Mørkve; Koplin, Jennifer; Pape, Kathrine; Skulstad, Svein Magne; Timm, Signe; Tjalvin, Gro; Krauss-Etschmann, Susanne; Accordini, Simone; Schlünssen, Vivi; Kirkeleit, Jorunn; Svanes, Cecilie (Journal article; Peer reviewed, 2021)
      Emerging research suggests environmental exposures before conception may adversely affect allergies and lung diseases in future generations. Most studies are limited as they have focused on single exposures, not considering ...
    • Exposures during the prepuberty period and future offspring's health: evidence from human cohort studies 

      Svanes, Cecilie; Bertelsen, Randi Jacobsen; Accordini, Simone; Holloway, John W.; Juliusson, Pétur Benedikt; Boateng, Eistine; Krauss-Etchmann, Susanne; Schlünssen, Vivi; Real, Francisco Gomez; Skulstad, Svein Magne (Journal article; Peer reviewed, 2021)
      Emerging evidence suggests that exposures in prepuberty, particularly in fathers-to-be, may impact the phenotype of future offspring. Analyses of the RHINESSA cohort find that offspring of father’s exposed to tobacco smoking ...
    • Longterm follow-up in European respiratory health studies - patterns and implications 

      Johannessen, Ane; Verlato, Guiseppe; Benediktsdottir, Bryndis; Forsberg, Bertil; Franklin, Karl; Gíslason, Thorainn; Holm, Mathias; Janson, Christer; Jögi, Rain; Lindberg, Eva; Macsali, Ferenc; Omenaas, Ernst; Gomez Real, Francisco; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Svanes, Cecilie; Torén, Kjell; Waatevik, Marie Johanne; Nilsen, Roy Miodini; de Marco, Roberto (Peer reviewed; Journal article, 2014-04-16)
      Background: Selection bias is a systematic error in epidemiologic studies that may seriously distort true measures of associations between exposure and disease. Observational studies are highly susceptible to selection ...
    • Maternal preconception occupational exposure to cleaning products and disinfectants and offspring asthma 

      Tjalvin, Gro; Svanes, Øistein; Igland, Jannicke; Bertelsen, Randi Jacobsen; Benediktsdóttir, Bryndís; Dharmage, Shyamali; Forsberg, Bertil; Holm, Mathias; Janson, Christer; Jögi, Nils Oskar; Johannessen, Ane; Malinovschi, Andrei; Pape, Kathrine; Real, Francisco Gomez; Sigsgaard, Torben; Torén, Kjell; Vindenes, Hilde Kristin; Zock, Jan-Paul; Schlünssen, Vivi; Svanes, Cecilie (Journal article; Peer reviewed, 2021)
      Background Emerging research suggests health effects in offspring after parental chemical exposures before conception. Many future mothers are exposed to potent chemicals at work, but potential offspring health effects ...
    • Menopause as a predictor of new-onset asthma 

      Triebner, Kai; Johannessen, Ane; Puggini, Luca; Benediktsdottir, Bryndis; Bertelsen, Randi Jacobsen; Bifulco, Ersilia; Dharmage, Shyamali C.; Franklin, Karl A.; Gislason, Þórarinn; Holm, Mathias; Jarvis, Deborah; Leynaert, Bénédicte; Lindberg, Eva; Macsali, Ferenc; Malinovschi, Andrej; Norbäck, Dan; Omenaas, Ernst; Rodriguez, Francisco J; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Wieslander, Gunilla; Zemp, Elisabeth; Svanes, Cecilie; Hustad, Simon Steinar; Gomez Real, Francisco (Peer reviewed; Journal article, 2015-01)
      Background: There is limited and conflicting evidence on the effect of menopause on asthma. Objectives: We sought to study whether the incidence of asthma and respiratory symptoms differ by menopausal status in a longitudinal ...
    • Nasal symptoms increase the risk of snoring and snoring increases the risk of nasal symptoms. A longitudinal population study 

      Värendh, Maria; Janson, Christer; Bengtsson, Caroline; Hellgren, Johan; Holm, Mathias; Schlünssen, Vivi; Johannessen, Ane; Franklin, Karl A.; Storaas, Torgeir; Jõgi, Rain; Gislason, Thorarinn; Lindberg, Eva (Journal article; Peer reviewed, 2021)
      Purpose Humans have a preference for nasal breathing during sleep. This 10-year prospective study aimed to determine if nasal symptoms can predict snoring and also if snoring can predict development of nasal symptoms. The ...
    • Parents’ smoking onset before conception as related to body mass index and fat mass in adult offspring: Findings from the RHINESSA generation study 

      Knudsen, Gerd Toril Mørkve; Dharmage, Shyamali C.; Janson, Christer; Abramson, Michael J.; Benediktsdóttir, Bryndís; Malinovschi, Andrei; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Real, Francisco Gomez; Schlünssen, Vivi; Jögi, Nils Oskar; Sánchez-Ramos, José Luis; Holm, Mathias; Garcia-Aymerich, Judith; Forsberg, Bertil; Svanes, Cecilie; Johannessen, Ane (Journal article; Peer reviewed, 2020)
      Emerging evidence suggests that parents’ preconception exposures may influence offspring health. We aimed to investigate maternal and paternal smoking onset in specific time windows in relation to offspring body mass index ...
    • Personal inhalable dust and endotoxin exposure among workers in an integrated textile factory 

      Zele, Yifokire Tefera; Schlünssen, Vivi; Kumie, Abera; Deressa, Wakgari; Moen, Bente Elisabeth; Bråtveit, Magne (Journal article; Peer reviewed, 2020)
      The aim of this study was to determine personal exposure to inhalable dust and endotoxin levels among workers in an integrated cotton-processing textile factory and exposure variability across the different work sections. ...
    • Place of upbringing in early childhood as related to inflammatory bowel diseases in adulthood: A population-based cohort study in Northern Europe 

      Timm, Signe; Svanes, Cecilie; Janson, Christer; Sigsgaard, Torben; Johannessen, Ane; Gíslason, Thorarinn; Jõgi, Rain; Omenaas, Ernst; Forsberg, Bertil; Torén, Kjell; Holm, Mathias; Bråbäck, Lennart; Schlünssen, Vivi (Peer reviewed; Journal article, 2014-06)
      Background The two inflammatory bowel diseases (IBD), ulcerative colitis and Crohn's disease, has increased rapidly during the twentieth century, but the aetiology is still poorly understood. Impaired immunological competence ...
    • Premature menopause and autoimmune primary ovarian insufficiency in two international multi-center cohorts 

      Vogt, Elinor Margrethe Chelsom; Real, Francisco Gomez; Husebye, Eystein Sverre; Björnsdottir, Sigridur; Benediktsdottir, Bryndis; Bertelsen, Randi Jacobsen; Demoly, Pascal; Franklin, Karl Anders; Gallastegui, Leire Sainz de Aja; González, Francisco Javier Callejas; Heinrich, Joachim; Holm, Mathias; Jögi, Nils Oskar; Leynaert, Benedicte; Lindberg, Eva; Malinovschi, Andrei; Martínez-Moratalla, Jesús; Mayoral, Raúl Godoy; Oudin, Anna; Pereira-Vega, Antonio; Semjen, Chantal Raherison; Schlünssen, Vivi; Triebner, Kai Philipp; Øksnes, Marianne (Journal article; Peer reviewed, 2022)
      Objective To investigate markers of premature menopause (<40 years) and specifically the prevalence of autoimmune primary ovarian insufficiency (POI) in European women. Design Postmenopausal women were categorized ...