Browsing Bergen Open Research Archive by Author "Schork, Andrew J."

Now showing items 1-8 of 8

    • 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans 

      Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi; Ellegaard, Maria; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J.; Bernard, Manon; Blackburn, Nicholas B.; Blangero, John; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Bülow, Robin; Bøen, Rune; Cahn, Wiepke; Calhoun, Vince D.; Caspers, Svenja; Ching, Christopher R. K.; Cichon, Sven; Ciufolini, Simone; Crespo-Facorro, Benedicto; Curran, Joanne E.; Dale, Anders M.; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J. C.; Zubicaray, Greig I. de; Zwarte, Sonja M. C. de; Desrivieres, Sylvane; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fejgin, Kim; Fisher, Simon E.; Fladby, Tormod; Frei, Oleksandr; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Groenewold, Nynke A.; Gustafsson, Omar; Haavik, Jan; Haberg, Asta Kristine; Hall, Jeremy; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Hibar, Derrek P.; Hillegers, Manon H. J.; Hoffmann, Per; Holleran, Laurena; Holmes, Avram J.; Johansson, Stefan; Jönsson, Erik Gunnar; Hellard, Stephanie Francoise Claire Le; Lundervold, Arvid; Lundervold, Astri J.; Moberget, Torgeir; Nordvik, Jan Egil; Sando, Sigrid Botne; Steen, Vidar Martin; Tamnes, Christian Krog; Agartz, Ingrid; Djurovic, Srdjan; Westlye, Lars Tjelta; Andreassen, Ole; Homuth, Georg; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E.; Ikeda, Masashi; Jahanshad, Neda; Jockwitz, Christiane; Jørgensen, Niklas R.; Kikuchi, Masataka; Knowles, Emma E. M.; Kumar, Kuldeep; Leu, Costin; Linden, David E. J.; Liu, Jingyu; Maillard, Anne M.; Martin, Nicholas G.; Martin-Brevet, Sandra; Mather, Karen A.; Mathias, Samuel R.; McMahon, Katie L.; McRae, Allan F.; Medland, Sarah E.; Meyer-Lindenberg, Andreas; Modenato, Claudia; Monereo Sánchez, Jennifer; Morris, Derek W.; Mühleisen, Thomas W.; Murray, Robin M.; Nielsen, Jacob; Nyberg, Lars; Olde Loohuis, Loes M.; Ophoff, Roel A.; Owen, Michael J.; Paus, Tomas; Pausova, Zdenka; Peralta, Juan M.; Pike, G. Bruce; Prieto, Carlos; Quinlan, Erin B.; Reinbold, Céline S.; Reis Marques, Tiago; Rucker, James J. H.; Sachdev, Perminder S.; Schofield, Peter R.; Schork, Andrew J.; Schumann, Gunter; Shin, Jean; Shumskaya, Elena; Silva, Ana I.; Sisodiya, Sanjay M.; Stein, Dan J.; Strike, Lachlan T.; Suzuki, Ikuo K.; Teumer, Alexander; Thalamuthu, Anbupalam; Tordesillas-Gutiérrez, Diana; Uhlmann, Anne; Ulfarsson, Magnus O.; van ‘t Ent, Dennis; van den Bree, Marianne B. M.; Vanderhaeghen, Pierre; Vassos, Evangelos; Wen, Wei; Wittfeld, Katharina; Wright, Margaret J.; Stefansson, Hreinn; Stefansson, Kari; Jacquemont, Sébastien; Thompson, Paul M. (Journal article; Peer reviewed, 2021)
      Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...

    • Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms 

      Andreassen, Ole Andreas; Desikan, Rahul S.; Wang, Yunpeng; Thompson, Wesley K.; Schork, Andrew J.; Zuber, Verena; Doncheva, Nadezhda T.; Ellinghaus, E.va; Mattingsdal, Morten; Franke, Andre; Lie, Benedicte. A.; Mills, Ian Geoffrey; Aukrust, Pål; McEvoy, Linda K.; Djurovic, Srdjan; Karlsen, Tom Hemming; Dale, Anders M. (Peer reviewed; Journal article, 2015-04-08)
      Epidemiological studies suggest a relationship between blood lipids and immune-mediated diseases, but the nature of these associations is not well understood. We used genome-wide association studies (GWAS) to investigate ...

    • Conservation of Distinct Genetically-Mediated Human Cortical Pattern 

      Qian, Peng; Schork, Andrew J.; Bartsch, Hauke; Lo, Min-Tzu; Panizzon, Matthew S.; Westlye, Lars Tjelta; Kremen, William S.; Jernigan, Terry L.; Le Hellard, Stephanie; Steen, Vidar Martin; Espeseth, Thomas; Huentelman, Matt; Håberg, Asta; Agartz, Ingrid; Djurovic, Srdjan; Andreassen, Ole Andreas; Dale, Anders; Schork, Nicholas J.; Chen, Chi-Hua; Schork, Nicholas J (Peer reviewed; Journal article, 2016-07-26)
      The many subcomponents of the human cortex are known to follow an anatomical pattern and functional relationship that appears to be highly conserved between individuals. This suggests that this pattern and the relationship ...

    • Enrichment of genetic markers of recent human evolution in educational and cognitive traits 

      Srinivasan, Saurabh; Bettella, Francesco; Frei, Oleksandr; Hill, W. David; Wang, Yunpeng; Witoelar, Aree; Schork, Andrew J.; Thompson, Wesley Kurt; Davies, Gail; Desikan, Rahul S.; Deary, Ian J.; Melle, Ingrid; Ueland, Torill; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2018-08-22)
      Higher cognitive functions are regarded as one of the main distinctive traits of humans. Evidence for the cognitive evolution of human beings is mainly based on fossil records of an expanding cranium and an increasing ...

    • Large-scale genomics unveil polygenic architecture of human cortical surface area 

      Chen, Chi-Hua; Peng, Qian; Schork, Andrew J.; Lo, Min-Tzu; Fan, Chun-Chieh; Wang, Yunpeng; Desikan, Rahul S.; Bettella, Franscesco; Hagler, Donald J.; Westlye, Lars Tjelta; Kremen, William S.; Jernigan, Terry L.; Le Hellard, Stephanie; Steen, Vidar Martin; Espeseth, Thomas; Huentelman, Matt; Håberg, Asta; Agartz, Ingrid; Djurovic, Srdjan; Andreassen, Ole Andreas; Schork, Nicholas; Dale, Anders (Peer reviewed; Journal article, 2015-07-20)
      Little is known about how genetic variation contributes to neuroanatomical variability, and whether particular genomic regions comprising genes or evolutionarily conserved elements are enriched for effects that influence ...

    • Polygenic overlap between C-reactive protein, plasma lipids, and Alzheimer disease 

      Desikan, Rahul S.; Schork, Andrew J.; Wang, Yunpeng; Thompson, Wesley K.; Dehghan, Abbas; Ridker, Paul M.; Chasman, Daniel I.; McEvoy, Linda K.; Holland, Dominic; Chen, Chi-Hua; Karow, David S.; Brewer, James B.; Hess, Christopher P.; Williams, Julie; Sims, Rebecca; O'Donovan, Michael C.; Choi, Seung Hoan; Bis, Joshua C.; Ikram, M. Arfan; Gudnason, Vilmundur; DeStefano, Anita L.; Van Der Lee, Sven J.; Psaty, Bruce M.; Van Duijn, Cornelia M.; Launer, Lenore; Seshadri, Sudha; Pericak-Vance, Margaret A.; Mayeux, Richard; Haines, Jonathan L.; Farrer, Lindsay A.; Hardy, John; Ulstein, Ingun; Aarsland, Dag; Fladby, Tormod; White, Linda; Sando, Sigrid Botne; Rongve, Arvid; Witoelar, Aree; Djurovic, Srdjan; Hyman, Bradley T.; Snædal, Jon; Steinberg, Stacy; Stefansson, Hreinn; Stefánsson, Kári; Schellenberg, Gerard D.; Andreassen, Ole Andreas; Dale, Anders (Peer reviewed; Journal article, 2015-06)
      Background—Epidemiological findings suggest a relationship between Alzheimer disease (AD), inflammation, and dyslipidemia, although the nature of this relationship is not well understood. We investigated whether this ...

    • Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration 

      Liu, Xueping; Helenius, Dorte; Skotte, Line; Beaumont, Robin N.; Wielscher, Matthias; Geller, Frank; Juodakis, Julius; Mahajan, Anubha; Bradfield, Jonathan P.; Lin, Frederick T.J.; Vogelezang, Suzanne; Bustamante, Mariona; Ahluwalia, Tarunveer S.; Pitkänen, Niina; Wang, Carol A.; Bacelis, Jonas; Borges, Maria C.; Zhang, Ge; Bedell, Bruce A.; Rossi, Robert M.; Skogstrand, Kristin; Peng, Shouneng; Thompson, Wesley Kurt; Appadurai, Vivek; Lawlor, Debbie A.; Kalliala, Ilkka; Power, Christine; McCarthy, Mark I.; Boyd, Heather A.; Marazita, Mary L.; Hakonarson, Hakon; Hayes, M. Geoffrey; Scholtens, Denise M.; Rivadeneira, Fernando; Jaddoe, Vincent W.V.; Vinding, Rebecca K.; Bisgaard, Hans; Knight, Bridget A.; Pahkala, Katja; Raitakari, Olli; Helgeland, Øyvind; Johansson, Stefan; Njølstad, Pål Rasmus; Fadista, João; Schork, Andrew J.; Nudel, Ron; Miller, Daniel E.; Chen, Xiaoting; Weirauch, Matthew T.; Mortensen, Preben Bo; Børglum, Anders D.; Nordentoft, Merete; Mors, Ole; Hao, Ke; Ryckman, Kelli K.; Hougaard, David M.; Kottyan, Leah C.; Pennell, Craig E.; Lyytikäinen, Leo-Pekka; Bønnelykke, Klaus; Vrijheid, Martine; Felix, Janine F.; Lowe, William L.; Grant, Struan F.A.; Hyppönen, Elina; Jacobsson, Bo; Jarvelin, Marjo-Riitta; Muglia, Louis J.; Murray, Jeffrey C.; Freathy, Rachel M.; Werge, Thomas M.; Melbye, Mads; Buil, Alfonso; Feenstra, Bjarke (Peer reviewed; Journal article, 2019-09-02)
      The duration of pregnancy is influenced by fetal and maternal genetic and non-genetic factors. Here we report a fetal genome-wide association meta-analysis of gestational duration, and early preterm, preterm, and postterm ...

    • Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: A proof of concept for multivariate endophenotypes 

      Fan, Chun Chieh; Schork, Andrew J.; Brown, Timothy T.; Spencer, Barbara E.; Akshoomoff, Natacha; Chen, Chi-Hua; Kuperman, Joshua M.; Hagler, Donald J.; Steen, Vidar Martin; Le Hellard, Stephanie; Håberg, Asta; Espeseth, Thomas; Andreassen, Ole Andreas; Dale, Anders; Jernigan, Terry L.; Halgren, Eric (Peer reviewed; Journal article, 2018-06-08)
      Despite great interest in using magnetic resonance imaging (MRI) for studying the effects of genes on brain structure in humans, current approaches have focused almost entirely on predefined regions of interest and had ...