Blar i Bergen Open Research Archive på forfatter "Schuck de Azevedo, Bruna"
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On the hunt for metalloenzyme inhibitors: Investigating the presence of metal-coordinating compounds in screening libraries and chemical spaces
Schuck de Azevedo, Bruna; Brenk, Ruth (Journal article; Peer reviewed, 2024)Metalloenzymes play vital roles in various biological processes, requiring the search for inhibitors to develop treatment options for diverse diseases. While compound library screening is a conventional approach, the ... -
Structure-based design of 1-deoxy-D-xylulose 5-phosphate reductoisomerase ligands
Schuck de Azevedo, Bruna (Doctoral thesis, 2024-08-29)The widespread use of antibiotics has undoubtedly saved countless lives over the last century. However, their indiscriminate use has contributed to the emergence of antimicrobial resistance (AMR), posing a significant ...