Browsing Bergen Open Research Archive by Author "Selvam, Sumithra"
Now showing items 1-6 of 6
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Host blood RNA transcript and protein signatures for sputum-independent diagnostics of tuberculosis in adults
Sivakumaran, Dhanasekaran; Ritz, Christian; Gjøen, John Espen; Vaz, Mario; Selvam, Sumithra; Ottenhoff, Tom H.M.; Doherty, Timothy Mark; Jenum, Synne; Grewal, Harleen (Journal article; Peer reviewed, 2021)To achieve the ambitious targets for tuberculosis (TB) prevention, care, and control stated by the End TB Strategy, new health care strategies, diagnostic tools are warranted. Host-derived biosignatures are explored for ... -
Identification of subclinical tuberculosis in household contacts using exposure scores and contact investigations
Bekken, Gry Klouman; Ritz, Christian; Selvam, Sumithra; Jesuraj, Nelson; Hesseling, Anneke; Doherty, T. Mark; Grewal, Harleen; Vaz, Mario; Jenum, Synne (Journal article; Peer reviewed, 2020-01-31)Background: The goal of tuberculosis elimination put forward in the End TB Strategy prioritizes diagnosis and treatment of incipient and subclinical TB, recently defined by key stakeholders as “asymptomatic, early pre-clinical ... -
Incidence of tuberculosis among school-going adolescents in South India
Uppada, Dharma R.; Selvam, Sumithra; Jesuraj, Nelson; Lau, Esther L.; Doherty, T. M.; Grewal, Harleen; Vaz, Mario; Lindtjørn, Bernt (Peer reviewed; Journal article, 2016-07-26)Background: Tuberculosis (TB) incidence data in vaccine target populations, particularly adolescents, are important for designing and powering vaccine clinical trials. Little is known about the incidence of tuberculosis ... -
Influence of Age and Nutritional Status on the Performance of the Tuberculin Skin Test and QuantiFERON®-TB Gold In-Tube in Young Children Evaluated for Tuberculosis in Southern India.
Jenum, Synne; Selvam, Sumithra; Mahelai, Diana; Jesuraj, Nelson; Cardenas, Vicky; Kenneth, John; Hesseling, Anneke C.; Doherty, Tanya Mark; Vaz, Mario; Grewal, Harleen (Peer reviewed; Journal article, 2014-10)Background: Reliable identification of Mycobacterium tuberculosis infection or tuberculosis (TB) disease in young children is vital to assure adequate preventive and curative treatment. The tuberculin skin test (TST) and ... -
The tuberculin skin test in school going adolescents in South India: associations of socio-demographic and clinical characteristics with TST positivity and non-response
Uppada, Dharma Rao; Selvam, Sumithra; Jesuraj, Nelson; Bennett, Sean; Verver, Suzanne; Grewal, Harleen; Vaz, Mario (Peer reviewed; Journal article, 2014-11-18)Background. India has generally used 1 TU purified protein derivative (PPD) as opposed to 2 TU PPD globally, limiting comparisons. It is important to assess latent TB infection in adolescents given that they may be a target ... -
The tuberculin skin test in school going adolescents in South India: associations of socio-demographic and clinical characteristics with TST positivity and non-response
Uppada, Dharma Rao; Selvam, Sumithra; Jesuraj, Nelson; Bennett, Sean; Verver, Suzanne; Grewal, Harleen M. S.; Vaz, Mario; TB Trials Study Group (Peer reviewed; Journal article, 2014-11-18)Background: India has generally used 1 TU purified protein derivative (PPD) as opposed to 2 TU PPD globally, limiting comparisons. It is important to assess latent TB infection in adolescents given that they may be a target ...