Browsing Bergen Open Research Archive by Author "SenGupta, Tanima"
Now showing items 1-2 of 2
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Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology
SenGupta, Tanima; Palikaras, Konstantinos; Esbensen, Ying Q.; Konstantinidis, Georgios; Galindo, Francisco Jose Naranjo; Achanta, Kavya; Kassahun, Henok; Stavgiannoudaki, Ioanna; Bohr, Vilhelm A.; Akbari, Mansour; Gaare, Johannes; Tzoulis, Charalampos; Tavernarakis, Nektarios; Nilsen, Hilde (Journal article; Peer reviewed, 2021)Aging, genomic stress, and mitochondrial dysfunction are risk factors for neurodegenerative pathologies, such as Parkinson disease (PD). Although genomic instability is associated with aging and mitochondrial impairment, ... -
Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid
Forthun, Rakel Brendsdal; SenGupta, Tanima; Skjeldam, Hanne Kim; Lindvall, Jessica Margareta; McCormack, Emmet; Gjertsen, Bjørn Tore (Peer reviewed; Journal article, 2012-11-14)The mechanisms of successful epigenetic reprogramming in cancer are not well characterized as they involve coordinated removal of repressive marks and deposition of activating marks by a large number of histone and DNA ...