• AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells 

      Lotsberg, Maria Lie; Wnuk-Lipinska, Katarzyna; Terry, Stéphane; Tan, Tuan Zea; Lu, Ning; Trachsel-Moncho, Laura; Røsland, Gro Vatne; Siraji, Muntequa Ishtiaq; Hellesøy, Monica; Rayford, Austin James; Jacobsen, Kirstine; Ditzel, Henrik J; Vintermyr, Olav Karsten; Bivona, Trever G; Minna, John; Brekken, Rolf A; Baguley, Bruce; Micklem, David; Akslen, Lars A.; Gausdal, Gro; Simonsen, Anne; Thiery, Jean Paul; Chouaib, Salem; Lorens, James; Engelsen, Agnete (Journal article; Peer reviewed, 2020)
      Introduction Acquired cancer therapy resistance evolves under selection pressure of immune surveillance and favors mechanisms that promote drug resistance through cell survival and immune evasion. AXL receptor tyrosine ...
    • Investigating the role of vitamin K in Axl-mediated melanoma progression and chemotherapeutic resistance 

      Siraji, Muntequa Ishtiaq (Master thesis, 2018-06-29)
      Metastatic melanoma is a highly aggressive cancer with a very poor prognosis and current therapies remain inadequate. Norway is among the top five countries with the highest incidence of melanoma. Malignant cells carry ...
    • Structure to function analysis with antigenic characterization of a hypothetical protein, HPAG1_0576 from Helicobacter pylori HPAG1 

      Ashrafi, Hanan; Siraji, Muntequa Ishtiaq; Showva, Nazmir Nur; Hossain, Md. Mozamme; Hossan, Tareq; Hasan, Md. Ashraful; Shohael, Abdullah Mohammad; Shawan, Mohammad Mahfuz Ali Khan (Peer reviewed; Journal article, 2019-07-31)
      Helicobacter pylori, a unique gastric pathogen causing chronic inflammation in the gastric mucosa with a possibility to develop gastric cancer has one-third of its proteins still uncharacterized. In this study, a hypothetical ...