Browsing Bergen Open Research Archive by Author "Skorve, Jon"
Now showing items 1-11 of 11
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Changes in lipoprotein particle subclasses, standard lipids, and apolipoproteins after supplementation with n-3 or n-6 PUFAs in abdominal obesity: A randomized double-blind crossover study
Grytten, Elise; Laupsa-Borge, Johnny; Bohov, Pavol; Bjørndal, Bodil; Strand, Elin; Skorve, Jon; Nordrehaug, Jan Erik; Berge, Rolf Kristian; Rostrup, Espen; Mellgren, Gunnar; Dankel, Simon N; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2021)Background & aims Marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), lower circulating levels of triacylglycerols (TAGs), and the plant-derived ... -
Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice
Skorve, Jon; Hilvo, Mika; Vihervaara, Terhi; Burri, Lena; Bohov, Pavol; Tillander, Veronika; Bjørndal, Bodil; Suoniemi, Matti; Laaksonen, Reijo; Ekroos, Kim; Berge, Rolf Kristian; Alexson, Stefan E.H. (Peer reviewed; Journal article, 2015-08-11)Background: Marine food is an important source of omega-3 fatty acids with beneficial health effects. Oils from marine organisms have different fatty acid composition and differ in their molecular composition. Fish oil ... -
Fish oil and krill oil supplementations differentially regulate lipid catabolic and synthetic pathways in mice
Tillander, Veronika; Bjørndal, Bodil; Burri, Lena; Bohov, Pavol; Skorve, Jon; Berge, Rolf Kristian; Alexson, Stefan E. H. (Peer reviewed; Journal article, 2014-04-27)Background: Marine derived oils are rich in long-chain polyunsaturated omega-3 fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which have long been associated with health promoting ... -
A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation
Bjørndal, Bodil; Berge, Christ; Ramsvik, Marie Sannes; Svardal, Asbjørn; Bohov, Pavol; Skorve, Jon; Berge, Rolf Kristian (Peer reviewed; Journal article, 2013-10-07)Background: There is growing evidence that fish protein hydrolysate (FPH) diets affect mitochondrial fatty acid metabolism in animals. The aim of the study was to determine if FPH could influence fatty acid metabolism and ... -
A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats
Lindquist, Carine; Bjørndal, Bodil; Bakke, Hege Gilbø; Slettom, Grete; Karoliussen, Marie; Rustan, Arild; Thoresen, G. Hege; Skorve, Jon; Nygård, Ottar; Berge, Rolf Kristian (Peer reviewed; Journal article, 2019-09-24)A fatty acid analogue, 2-(tridec-12-yn-1-ylthio)acetic acid (1-triple TTA), was previously shown to have hypolipidemic effects in rats by targeting mitochondrial activity predominantly in liver. This study aimed to determine ... -
Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats
Bjune, Mona Synnøve; Lindquist, Carine; Stafsnes, Marit Hallvardsdotter; Bjørndal, Bodil; Bruheim, Per; Aloysius, Thomas Aquinas; Nygård, Ottar; Skorve, Jon; Madsen, Lise; Dankel, Simon N; Berge, Rolf Kristian (Journal article; Peer reviewed, 2021)Objective: Discovery of specific markers that reflect altered hepatic fatty acid oxidation could help to detect an individual's risk of fatty liver, type 2 diabetes and cardiovascular disease at an early stage. Lipid and ... -
The PPAR pan-agonist tetradecylthioacetic acid promotes redistribution of plasma cholesterol towards large HDL
Lundåsen, Thomas; Pedrelli, Matteo; Bjørndal, Bodil; Rozell, Björn; Kuiper, Raoul; Burri, Lena; Pavanello, Chiara; Turri, Marta; Skorve, Jon; Berge, Rolf Kristian; Alexson, Stefan E.H.; Tillander, Veronika (Journal article; Peer reviewed, 2020)Tetradecylthioacetic acid (TTA) is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including ... -
A protein extract from chicken reduces plasma homocysteine in rats
Lysne, Vegard; Bjørndal, Bodil; Vik, Rita; Nordrehaug, Jan Erik; Skorve, Jon; Nygård, Ottar; Berge, Rolf Kristian (Peer reviewed; Journal article, 2015-06-04)The present study aimed to evaluate effects of a water-soluble protein fraction of chicken (CP), with a low methionine/glycine ratio, on plasma homocysteine and metabolites related to homocysteine metabolism. Male Wistar ... -
A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in apoE-deficient mice
Parolini, Cinzia; Vik, Rita; Busnelli, Marco; Bjørndal, Bodil; Holm, Sverre; Brattelid, Trond; Manzini, Stefano; Ganzetti, Giulia S.; Dellera, Federica; Halvorsen, Bente; Aukrust, Pål; Sirtori, Cesare R.; Nordrehaug, Jan Erik; Skorve, Jon; Berge, Rolf Kristian; Chiesa, Giulia (Peer reviewed; Journal article, 2014-05-19)Fish consumption is considered health beneficial as it decreases cardiovascular disease (CVD)-risk through effects on plasma lipids and inflammation. We investigated a salmon protein hydrolysate (SPH) that is hypothesized ... -
Tetradecylthiopropionic acid induces hepatic mitochondrial dysfunction and steatosis, accompanied by increased plasma homocysteine in mice
Berge, Rolf Kristian; Bjørndal, Bodil; Strand, Elin; Bohov, Pavol; Lindquist, Carine; Nordrehaug, Jan Erik; Svardal, Asbjørn; Skorve, Jon; Nygård, Ottar (Peer reviewed; Journal article, 2016-02-05)Background: Hepatic mitochondrial dysfunction plays an important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Methyl donor supplementation has been shown to alleviate NAFLD, connecting the condition ... -
Three differently generated salmon protein hydrolysates reveal opposite effects on hepatic lipid metabolism in mice fed a high-fat diet
Vik, Rita; Tilander, Veronika; Skorve, Jon; Vihervaara, Terhi; Ekroos, Kim; Alexson, Stefan E.H.; Berge, Rolf Kristian; Bjørndal, Bodil (Peer reviewed; Journal article, 2015-03-17)This study investigates the effects of salmon peptide fractions, generated using different enzymatic hydrolyzation methods, on hepatic lipid metabolism. Four groups of mice were fed a high-fat diet with 20% casein (control ...