• Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations 

      Bergland, Ola Undrum; Halvorsen, Lene Vernås; Søraas, Camilla Lund; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Rognstad, Stine; Brobak, Karl Marius; Aune, Arleen; Olsen, Eirik; Fauchald, Ylva; Heimark, Sondre; Thorstensen, Christian W; Liestøl, Knut; Solbu, Marit Dahl; Gerdts, Eva; Mo, Rune; Rostrup, Morten; Kjeldsen, Sverre; Høieggen, Aud; Opdal, Mimi Stokke; Fadl Elmula, Fadl Elmula M. (Journal article; Peer reviewed, 2021)
      Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in ...
    • Effect of Therapeutic Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial 

      Halvorsen, Lene Vernås; Søraas, Camilla Lund; Larstorp, Anne Cecilie Kjeldsen; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Liestøl, Knut; Aune, Arleen; Olsen, Erik; Brobak, Karl Marius; Bergland, Ola Undrum; Rognstad, Stine; Aarskog, Nikolai Ravn; Heimark, Sondre; Fadl Elmula, Fadl Elmula M.; Gerdts, Eva; Mo, Rune; Solbu, Marit Dahl; Opdal, Mimi Stokke; Kjeldsen, Sverre; Rostrup, Morten; Høieggen, Aud (Journal article; Peer reviewed, 2024)
      Background: Drug concentration in blood or urine is an acknowledged method to detect nonadherence. Observational studies suggest that informing patients about low or absent serum drug levels improves blood pressure (BP). ...
    • Novel biomarkers in patients with uncontrolled hypertension with and without kidney damage 

      Brobak, Karl Marius; Halvorsen, Lene Vernås; Aass, Hans Christian; Søraas, Camilla Lund; Aune, Arleen; Olsen, Erik; Bergland, Ola Undrum; Rognstad, Stine; Blom, Kjersti Benedicte; Birkeland, Jon Arne; Høieggen, Aud; Larstorp, Anne Cecilie Kjeldsen; Solbu, Marit Dahl (Journal article; Peer reviewed, 2024)
      Introduction Estimated glomerular filtration rate (eGFR) and urine albumin/creatinine ratio (ACR) are insensitive biomarkers for early detection of hypertension-mediated organ damage (HMOD). In this nationwide cross-sectional ...