Blar i Bergen Open Research Archive på forfatter "Solheim, Eirik Tveit"
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Altered exosomal miRNA profiles in patients with paraneoplastic cerebellar degeneration
Solheim, Eirik Tveit; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Anandan, Shamundeeswari; Peter, Elise; Desestret, Virginie; Totland, Cecilie; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2024)Objective Patients with ovarian cancer (OC) may develop anti-Yo-associated paraneoplastic cerebellar degeneration (PCD)—a cerebellar ataxia associated with tumor-induced autoimmunity against CDR2 and CDR2L proteins. ... -
Multi-omics profiling reveals dysregulated ribosome biogenesis and impaired cell proliferation following knockout of CDR2L
Solheim, Eirik Tveit; Gerking, Yola; Kråkenes, Torbjørn; Herdlevær, Ida; Birkeland, Even; Totland, Cecilie; Dick, Fiona; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2024)Background Cerebellar degeneration-related (CDR) proteins are associated with paraneoplastic cerebellar degeneration (PCD) – a rare, neurodegenerative disease caused by tumour-induced autoimmunity against neural antigens ... -
Paraneoplastic cerebellar degeneration: Exploring the roles of the cerebellar degeneration-related proteins and exosomal microRNAs
Solheim, Eirik Tveit (Doctoral thesis, 2024-12-10)Bakgrunn: Paraneoplastisk cerebellær degenerasjon (PCD) er eit av dei vanlegaste paraneoplastiske nevrologiske syndroma - ei gruppe sjeldne, immunmedierte syndrom assosiert med kreft. Individ med PCD har autoantistoff i ...