• Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study 

      Mehl, Arne; Åsvold, Bjørn Olav; Lydersen, Stian; Paulsen, Julie; Solligård, Erik; Damås, Jan Kristian; Harthug, Stig; Edna, Tom-Harald (Peer reviewed; Journal article, 2017-03-11)
      Background: Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time. Methods: We studied the burden of disease and death related to BSI in a ...
    • Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study 

      Husabø, Gunnar; Nilsen, Roy Miodini; Flaatten, Hans; Solligård, Erik; Frich, Jan C; Bondevik, Gunnar Tschudi; Braut, Geir Sverre; Walshe, Kieran; Harthug, Stig; Hovlid, Einar (Peer reviewed; Journal article, 2020-01-22)
      Background: Early recognition of sepsis is critical for timely initiation of treatment. The first objective of this study was to assess the timeliness of diagnostic procedures for recognizing sepsis in emergency departments. ...
    • Effects of external inspections on sepsis detection and treatment: a stepped-wedge study With cluster-level randomisation 

      Husabø, Gunnar; Nilsen, Roy Miodini; Solligård, Erik; Flaatten, Hans; Walshe, Kieran; Frich, Jan C; Bondevik, Gunnar Tschudi; Braut, Geir Sverre; Helgeland, Jon; Harthug, Stig; Hovlid, Einar (Journal article; Peer reviewed, 2020)
      Objective To evaluate the effects of external inspections on (1) hospital emergency departments’ clinical processes for detecting and treating sepsis and (2) length of hospital stay and 30-day mortality. Design Incomplete ...
    • Mapping the human genetic architecture of COVID-19 

      Niemi, Mari E.K.; Karjalainen, Juha; Liao, Rachel G.; Neale, Benjamin M.; Daly, Mark; Ganna, Andrea; Pathak, Gita A.; Andrews, Shea J.; Kanai, Masahiro; Veerapen, Kumar; Fernandez-Cadenas, Israel; Schulte, Eva C.; Striano, Pasquale; Afset, Jan Egil; Solligård, Erik; Damås, Jan Kristian; Risnes, Kari; Bettini, Laura Rachele; Gustad, Lise Tuset; Holter, Jan Cato; Hov, Johannes Espolin Roksund; Karlsen, Tom Hemming; Folseraas, Trine; Holten, Aleksander Rygh; Dyrhol-Riise, Anne Ma; Tonby, Kristian; Lind, Andreas; Müller, Fredrik; Dudman, Susanne Gjeruldsen; Grimsrud, Marit Mæhle; Vadla, May Sissel; Myhre, Ronny; Kildal, Anders Benjamin; Hoff, Dag Arne Lihaug; Muller, Karl Erik; Heggelund, Lars; Bergan, Jonas; Skogen, Vegard (Journal article; Peer reviewed, 2021)
      The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity ...
    • Prior statin use and 90-day mortality in Gram-negative and Gram-positive bloodstream infection: a prospective observational study 

      Mehl, Arne; Harthug, Stig; Lydersen, Stian; Paulsen, Julie; Åsvold, Bjørn Olav; Solligård, Erik; Damås, Jan Kristian; Edna, Tom-Harald (Peer reviewed; Journal article, 2015-03)
      n several studies on patients with bloodstream infection (BSI), prior use of statins has been associated with improved survival. Gram-positive and Gram-negative bacteria alert the innate immune system in different ways. ...
    • Trends in antimicrobial resistance and empiric antibiotic therapy of bloodstream infections at a general hospital in Mid-Norway: A prospective observational study 

      Mehl, Arne; Åsvold, Bjørn Olav; Kümmel, Angela; Lydersen, Stian; Paulsen, Julie; Haugan, Ingvild; Solligård, Erik; Damås, Jan Kristian; Harthug, Stig; Edna, Tom-Harald (Peer reviewed; Journal article, 2017-02-02)
      Background: The occurrence of bloodstream infection (BSI) and antimicrobial resistance have been increasing in many countries. We studied trends in antimicrobial resistance and empiric antibiotic therapy at a medium-sized ...