Blar i Bergen Open Research Archive på forfatter "Solvang, Stein-Erik Hafstad"

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    • Delirium is frequently underdiagnosed among older hospitalised patients despite available information in hospital medical records 

      Titlestad, Irit; Haugarvoll, Kristoffer; Solvang, Stein-Erik Hafstad; Norekvål, Tone Merete; Skogseth, Ragnhild Eide; Andreassen, Ole A; Årsland, Dag; Neerland, Bjørn Erik; Nordrehaug, Jan Erik; Tell, Grethe S; Giil, Lasse Melvær (Journal article; Peer reviewed, 2024)
      Background In-hospital delirium is associated with adverse outcomes and is underdiagnosed, limiting research and clinical follow-up. Objective To compare the incidence of in-hospital delirium determined by chart-based ...

    • The kynurenine pathway in cognition, dementia, and aging 

      Solvang, Stein-Erik Hafstad (Doctoral thesis, 2021-06-16)
      Background: Experimental studies implicate the kynurenine pathway in cognitive function, dementia, aging, and longevity. Comparatively, clinical studies are few and most lack comprehensive targeted metabolomic profiling ...

    • Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging 

      Solvang, Stein-Erik Hafstad; Hodge, Allison; Watne, Leiv; Cabral-Marques, Otavio; Nordrehaug, Jan Erik; Giles, Graham G.; Dugué, Pierre-Antoine; Nygård, Ottar Kjell; Ueland, Per Magne; McCann, Adrian; Idland, Ane-Victoria; Midttun, Øivind; Ulvik, Arve; Halaas, Nathalie Bodd; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2022)
      The kynurenine pathway is implicated in aging, longevity, and immune regulation, but longitudinal studies and assessment of the cerebrospinal fluid (CSF) are lacking. We investigated tryptophan (Trp) and downstream kynurenine ...

    • Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia 

      Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Aarsland, Dag; Lange, Johannes; Ueland, Per Magne; McCann, Adrian; Midttun, Øivind; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2019)
      Introduction: Circulating tryptophan (Trp) and its downstream metabolites, the kynurenines, are potentially neuroactive. Consequently, they could be associated with neuropsychiatric symptoms and cognitive prognosis in ...

    • Sex-specific associations of kynurenic acid with neopterin in Alzheimer’s disease 

      Knapskog, Anne-Brita; Edwin, Trine Holt; Ueland, Per Magne; Ulvik, Arve; Fang, Fei; Eldholm, Rannveig Sakshaug; Halaas, Nathalie Bodd; Solvang, Stein-Erik Hafstad; Saltvedt, Ingvild Tina; Watne, Leiv; Aksnes, Mari (Journal article; Peer reviewed, 2024-07-27)
      Background: Sex differences in neuroinflammation could contribute to women’s increased risk of Alzheimer’s disease (AD), providing rationale for exploring sex-specific AD biomarkers. In AD, dysregulation of the kynurenine ...