Browsing Bergen Open Research Archive by Author "Specht, Karsten"
Now showing items 1-20 of 52
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Abnormal phasic activity in saliency network, motor areas, and basal ganglia in Parkinson's disease during rhythm perception
Vikene, Kjetil; Skeie, Geir Olve; Specht, Karsten (Peer reviewed; Journal article, 2019)Behavioral studies indicate that persons with Parkinson's disease have complexity dependent problems with the discrimination of auditory rhythms. Furthermore, neuroimaging studies show that rhythm processing activates many ... -
Adults with attention-deficit/hyperactivity disorder. A brain magnetic resonance spectroscopy study
Dramsdahl, Margaretha; Ersland, Lars; Plessen, Kerstin von; Haavik, Jan; Hugdahl, Kenneth; Specht, Karsten (Peer reviewed; Journal article, 2011-11-23)Background: Impaired cognitive control in individuals with attention-deficit/hyperactivity disorder (ADHD) may be related to a prefrontal cortical glutamatergic deficit. We assessed the glutamate level in the left and the ... -
Altered resting state effective connectivity of anterior insula in depression
Kandilarova, Sevdalina; Stoyanov, Drozdstoy; Kostianev, Stefan; Specht, Karsten (Peer reviewed; Journal article, 2018-03-15)Depression has been associated with changes in both functional and effective connectivity of large scale brain networks, including the default mode network, executive network, and salience network. However, studies of ... -
Arterial spin labelling shows functional depression of non-lesion tissue in chronic Wernicke's aphasia
Robson, Holly; Specht, Karsten; Beaumont, Helen; Parkes, Laura M.; Sage, Karen; Lambon Ralph, Matthew A.; Zahn, Roland (Peer reviewed; Journal article, 2017-07)Behavioural impairment post-stroke is a consequence of structural damage and altered functional network dynamics. Hypoperfusion of intact neural tissue is frequently observed in acute stroke, indicating reduced functional ... -
Associations between lesion size, lesion location and aphasia in acute stroke
Døli, Hedda; Helland, Wenche A.; Helland, Turid; Specht, Karsten (Journal article; Peer reviewed, 2020)Background: The localization and organization of language has been an ongoing research interest ever since the early findings of Paul Broca. The emergence of neuroimaging the past 20 years has given us new insights on the ... -
Associations between stroke severity, aphasia severity, lesion location, and lesion size in acute stroke, and aphasia severity one year post stroke
Døli, Hedda; Helland, Wenche Andersen; Helland, Turid; Næss, Halvor; Hofstad, Håkon; Specht, Karsten (Journal article; Peer reviewed, 2021)Background The aim of the present study was to investigate the associations stroke severity, aphasia severity, lesion location and lesion size in acute stroke, and aphasia severity in the subacute and chronic stages post ... -
Children with dyslexia show cortical hyperactivation in response to increasing literacy processing demands
Morken, Frøydis; Helland, Turid; Hugdahl, Kenneth; Specht, Karsten (Peer reviewed; Journal article, 2014-12-22)This fMRI study aimed to examine how differences in literacy processing demands may affect cortical activation patterns in 11- to 12-year-old children with dyslexia as compared to children with typical reading skills. ... -
Combined fMRI Region- and Network-Analysis Reveal New Insights of Top-Down Modulation of Bottom-Up Processes in Auditory Laterality
Kazimierczak, Katarzyna; Craven, Alexander R.; Ersland, Lars; Specht, Karsten; Dumitru, Magda L.; Sandøy, Lydia B.; Hugdahl, Kenneth (Journal article; Peer reviewed, 2022)Dichotic listening along with the right-ear advantage (REA) has been a standard method of investigating auditory laterality ever since it was first introduced into neuropsychology in the early 1960s. Beginning in the 1980s, ... -
Compensatory task-specific hypersensitivity in bilateral planum temporale and right superior temporal gyrus during auditory rhythm and omission processing in Parkinson's disease
Vikene, Kjetil; Skeie, Geir Olve; Specht, Karsten (Peer reviewed; Journal article, 2019)Persons with Parkinson’s disease have general timing deficits and have difficulties in rhythm discrimination tasks. The basal ganglia, a crucial part of Parkinson’s disease pathology, is believed to play an important role ... -
Congenital prosopagnosia: multistage anatomical and functional deficits in face processing circuitry
Dinkelacker, V.; Grüter, M.; Klaver, P.; Grüter, T.; Specht, Karsten; Weis, S.; Kennerknecht, I.; Elger, C. E.; Fernandez, G. (Peer reviewed; Journal article, 2011)Face recognition is a primary social skill which depends on a distributed neural network. A pronounced face recognition deficit in the absence of any lesion is seen in congenital prosopagnosia. This study investigating 24 ... -
Considerations on brain age predictions from repeatedly sampled data across time
Korbmacher, Max; Wang, Mengyun; Eikeland, Rune; Buchert, Ralph; Andreassen, Ole; Espeseth, Thomas; Leonardsen, Esten Høyland; Westlye, Lars Tjelta; Maximov, Ivan; Specht, Karsten (Journal article; Peer reviewed, 2023)Introduction Brain age, the estimation of a person's age from magnetic resonance imaging (MRI) parameters, has been used as a general indicator of health. The marker requires however further validation for application in ... -
Cortical thickness and resting‐state cardiac function across the lifespan: A cross‐sectional pooled mega‐analysis
Koenig, Julian; Abler, Birgit; Agartz, Ingrid; Åkerstedt, Torbjørn; Andreassen, Ole Andreas; Anthony, Mia; Bär, Karl-Jürgen; Bertsch, Katja; Brown, Rebecca C.; Brunner, Romuald; Carnevali, Luca; Critchley, Hugo D.; Cullen, Kathryn R; de Geus, Eco J C; de la Cruz, Feliberto; Dziobek, Isabel; Ferger, Marc D.; Fischer, Håkan; Flor, Herta; Gaebler, Michael; Gianaros, Peter J.; Giummarra, Melita J.; Greening, Steven G.; Guendelman, Simon; Heathers, James A. J.; Herpertz, Sabine C.; Hu, Mandy X.; Jentschke, Sebastian; Kaess, Michael; Kaufmann, Tobias; Klimes-Dougan, Bonnie; Koelsch, Stefan; Krauch, Marlene; Kumral, Deniz; Lamers, Femke; Lee, Tae‐Ho; Lekander, Mats; Lin, Feng; Lotze, Martin; Makovac, Elena; Mancini, Matteo; Mancke, Falk; Månsson, Kristoffer N. T.; Manuck, Stephen B.; Mather, Mara; Meeten, Frances; Min, Jungwon; Mueller, Bryon A.; Muench, Vera; Nees, Frauke; Nga, Lin; Nilsonne, Gustav; Ordonez Acuna, Daniela; Osnes, Berge; Ottaviani, Cristina; Penninx, Brenda W J H; Ponzio, Allison; Poudel, Govinda R.; Reinelt, Janis; Ren, Ping; Sakaki, Michiko; Schumann, Andy; Sørensen, Lin; Specht, Karsten; Straub, Joana; Tamm, Sandra; Thai, Michelle; Thayer, Julian F.; Ubani, Benjamin; van der Mee, Denise J.; van Velzen, Laura S.; Ventura‐Bort, Carlos; Villringer, Arno; Watson, David R.; Wei, Luqing; Wendt, Julia; Westlund Schreiner, Melinda; Westlye, Lars Tjelta; Weymar, Mathias; Winkelmann, Tobias; Wu, Guo‐Rong; Yoo, Hyun Joo; Quintana, Daniel (Journal article; Peer reviewed, 2020)Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides important insights into neurovisceral mechanisms underlying health and disease. Resting‐state ... -
Current Challenges in Translational and Clinical fMRI and Future Directions
Specht, Karsten (Journal article; Peer reviewed, 2020)Translational neuroscience is an important field that brings together clinical praxis with neuroscience methods. In this review article, the focus will be on functional neuroimaging (fMRI) and its applicability in clinical ... -
Deep brain imaging of three participants across 1 year: The Bergen breakfast scanning club project
Wang, Meng-yun; Korbmacher, Max; Eikeland, Rune Andreas; Specht, Karsten (Journal article; Peer reviewed, 2022-10-17)Our understanding of the cognitive functions of the human brain has tremendously benefited from the population functional Magnetic Resonance Imaging (fMRI) studies in the last three decades. The reliability and replicability ... -
Default-mode network functional connectivity is closely related to metabolic activity
Passow, Susanne; Specht, Karsten; Adamsen, Tom Christian; Biermann, Martin; Brekke, Njål; Craven, Alexander R.; Ersland, Lars; Grüner, Renate; Kleven-Madsen, Nina; Kvernenes, Ole Heine; Schwarzlmüller, Thomas; Olesen, Rasmus Aamand; Hugdahl, Kenneth (Peer reviewed; Journal article, 2015-06)Over the last decade, the brain's default-mode network (DMN) and its function has attracted a lot of attention in the field of neuroscience. However, the exact underlying mechanisms of DMN functional connectivity, or more ... -
Dynamic up- and down-regulation of the default (DMN) and extrinsic (EMN) mode networks during alternating task-on and task-off periods
Hugdahl, Kenneth; Kazimierczak, Katarzyna Anna; Beresniewicz, Justyna; Kompus, Kristiina; Westerhausen, René; Ersland, Lars; Grüner, Renate; Specht, Karsten (Peer reviewed; Journal article, 2019)Using fMRI, Hugdahl et al. (2015) reported the existence of a general-domain cortical network during active task-processing which was non-specific to the cognitive task being processed. They labelled this network the ... -
Effective Connectivity Between the Orbitofrontal Cortex and the Precuneus Differentiates Major Psychiatric Disorders: Results from a Transdiagnostic Spectral DCM Study
Kandilarova, Sevdalina; Stoyanov, Drozdstoy; Aryutova, Katrin; Paunova, Rossitsa; Mantarkov, Mladen; Mitrev, Ivo; Todeva-Radneva, Anna; Specht, Karsten (Journal article; Peer reviewed, 2023)Background & Objective: We have previously identified aberrant connectivity of the left precuneus, ventrolateral prefrontal cortex, anterior cingulate cortex, and anterior insula in patients with either a paranoid ... -
The effects of alcohol intoxication on neuronal activation at different levels of cognitive load
Gundersen, Hilde; Grüner, Renate; Specht, Karsten; Hugdahl, Kenneth (Peer reviewed; Journal article, 2008-08-22)The aim of this study was to investigate how alcohol intoxication at two blood alcohol concentrations (BAC) affected neuronal activation during increasing levels of cognitive load. For this purpose we used functional ... -
Effects of Facial Symmetry and Gaze Direction on Perception of Social Attributes: A Study in Experimental Art History
Folgerø, Per Olav; Hodne, Lasse; Johansson, Christer; Andresen, Alf Edgar; Sætren, Lill Charlotte; Specht, Karsten; Skaar, Øystein Olav; Reber, Rolf (Journal article; Peer reviewed, 2016)This article explores the possibility of testing hypotheses about art production in the past by collecting data in the present. We call this enterprise “experimental art history”. Why did medieval artists prefer to paint ... -
Effects of music production on cortical plasticity within cognitive rehabilitation of patients with mild traumatic brain injury
Vik, Berit; Skeie, Geir Olve; Vikane, Eirik; Specht, Karsten (Journal article; Peer reviewed, 2018)Objective: We explored the effects of playing the piano on patients with cognitive impairment after mild traumatic brain injury (mTBI) and, addressed the question if this approach would stimulate neural networks in re-routing ...