Blar i Bergen Open Research Archive på forfatter "Spigset, Olav"
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Actigraphy assessment of motor activity and sleep in patients with alcohol withdrawal syndrome and the effects of intranasal oxytocin
Melby, Katrine; Fasmer, Ole Bernt; Henriksen, Tone Elise Gjøtterud; Gråwe, Rolf W.; Aamo, Trond Oskar; Spigset, Olav (Journal article; Peer reviewed, 2020)Background and aims The alcohol withdrawal syndrome increases autonomic activation and stress in patients during detoxification, leading to alterations in motor activity and sleep irregularities. Intranasal oxytocin has ... -
Adverse events with fatal outcome associated with alemtuzumab treatment in multiple sclerosis
Holmøy, Trygve; Fevang, Børre; Olsen, David Benee; Spigset, Olav; Bø, Lars (Peer reviewed; Journal article, 2019-08-12)Objective: Sporadic fatal adverse events have been reported during treatment of multiple sclerosis with alemtuzumab. To provide a systematic overview, we searched the centralized European Medicines Agency database of ... -
Factors associated with time consumption when answering drug-related queries to Scandinavian drug information centres: a multi-centre study
Reppe, Linda Amundstuen; Spigset, Olav; Böttiger, Ylva; Christensen, Hanne Rolighed; Kampmann, Jens Peter; Damkier, Per; Lydersen, Stian; Schjøtt, Jan (Peer reviewed; Journal article, 2014-11)Purpose There is little research-based documentation on the services provided by drug information centres (DICs). The aim of this multi-centre study was to explore for the first time the factors associated with time ... -
Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero – the Norwegian Mother and Child Cohort Study
Husebye, Elisabeth Synnøve Nilsen; Gilhus, Nils Erik; Spigset, Olav; Daltveit, Anne Kjersti; Bjørk, Marte-Helene (Peer reviewed; Journal article, 2020)Background and purpose: The purpose was to examine the consequences of antiepileptic drug (AED) exposure during pregnancy on language abilities in children aged 5 and 8 years of mothers with epilepsy. Methods: The study ... -
Quality assessment of structure and language elements of written responses given by seven Scandinavian drug information centres
Reppe, Linda Amundstuen; Spigset, Olav; Kampmann, Jens Peter; Damkier, Per; Christensen, Hanne Rolighed; Böttiger, Ylva; Schjøtt, Jan (Peer reviewed; Journal article, 2017-05)Purpose: The aim of this study was to identify structure and language elements affecting the quality of responses from Scandinavian drug information centres (DICs). Methods: Six different fictitious drug-related queries ... -
Relationship Between Time Consumption and Quality of Responses to Drug-Related Queries: A Study From Seven Drug Information Centers in Scandinavia
Reppe, Linda Amundstuen; Lydersen, Stian; Schjøtt, Jan; Damkier, Per; Christensen, Hanne Rolighed; Kampmann, Jens Peter; Böttiger, Ylva; Spigset, Olav (Peer reviewed; Journal article, 2016-07)Purpose: The aims of this study were to assess the quality of responses produced by drug information centers (DICs) in Scandinavia, and to study the association between time consumption processing queries and the quality ... -
Use of References in Responses from Scandinavian Drug Information Centres
Schjøtt, Jan; Böttiger, Ylva; Damkier, Per; Reppe, Linda Amundstuen; Kampmann, Jens Peter; Christensen, Hanne Rolighed; Spigset, Olav (Journal article, 2018)Background: The aim of this study was to compare use of references in responses from Scandinavian drug information centres (DICs). Methods: Six different fictitious drug-related queries were sent to each of seven Scandinavian ... -
Using the Norwegian Mother and Child Cohort Study to determine risk factors for delayed development and neuro-psychiatric symptoms in the offspring of parents with epilepsy
Bjørk, Marte Helene; Veiby, Gyri; Spigset, Olav; Gilhus, Nils Erik (Peer reviewed; Journal article, 2014-12-29)Introduction: Antiepileptic drug (AED) teratogenicity is suspected to be the main cause of impaired development in children of women with epilepsy. However, many factors may confound the reported risks. The purpose of this ... -
Vascular risk factor control and adherence to secondary preventive medication after ischaemic stroke
Gynnild, Mari Nordbø; Aakerøy, Rachel; Spigset, Olav; Askim, Torunn; Beyer, Mona Kristiansen; Ihle-Hansen, Hege; Munthe-Kaas, Ragnhild; Knapskog, Anne Brita; Lydersen, Stian; Næss, Halvor; Røsstad, Tove Garåsen; Seljeseth, Yngve Müller; Thingstad, Pernille; Saltvedt, Ingvild; Ellekjær, Hanne (Journal article; Peer reviewed, 2021)Background Studies regarding adequacy of secondary stroke prevention are limited. We report medication adherence, risk factor control and factors influencing vascular risk profile following ischaemic stroke. Methods A ... -
Verbal abilities in children of mothers with epilepsy: Association to maternal folate status
Husebye, Elisabeth Synnøve Nilsen; Gilhus, Nils Erik; Riedel, Bettina; Spigset, Olav; Daltveit, Anne Kjersti; Bjørk, Marte-Helene (Peer reviewed; Journal article, 2018-08)Objective: To examine the effect of maternal folic acid supplementation and maternal plasma folate and antiepileptic drug (AED) concentrations on language delay in AED-exposed children of mothers with epilepsy. Methods: ... -
Vitamin B status and association with antiseizure medication in pregnant women with epilepsy
Husebye, Elisabeth Synnøve Nilsen; Riedel, Bettina Maria Ingeborg; Monsen, Anne-Lise Bjørke; Spigset, Olav; Daltveit, Anne Kjersti Nesje; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2021)Objective Antiseizure medication (ASM) use interacts with vitamin B status in nonpregnant epilepsy populations. We aimed to examine the association between ASM and vitamin B status in pregnant women with epilepsy. Methods ...