• DNA ploidy in curettage specimens identifies high-risk patients and lymph node metastasis in endometrial cancer 

      Njølstad, Tormund Salvesen; Trovik, Jone; Hveem, Tarjei Sveinsgjerd; Kjæreng, Marna Lill; Kildal, Wanja; Pradhan, Manohar; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Haugland, Hans Kristian; Eraker, Runar; Oddenes, Klaus; Rokne, Jan Anders; Tjugum, Jostein; Lode, Margaret Sævik; Amant, Frédéric; Werner, Henrica Maria Johanna; Salvesen, Helga Birgitte; Danielsen, Håvard Emil (Peer reviewed; Journal article, 2015-04-21)
      Background: Preoperative risk stratification is essential in tailoring endometrial cancer treatment, and biomarkers predicting lymph node metastasis and aggressive disease are aspired in clinical practice. DNA ploidy ...
    • Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients 

      Tangen, Ingvild Løberg; Kopperud, Reidun Kristin; Visser, Nicole C.M.; Staff, Anne Cathrine; Tingulstad, Solveig; Marcickiewicz, Janusz; Amant, Frédéric; Bjørge, Line; Pijnenborg, Johanna M.A.; Salvesen, Helga; Werner, Henrica Maria Johanna; Trovik, Jone; Krakstad, Camilla (Peer reviewed; Journal article, 2017-09)
      Background: Several studies have identified L1 cell adhesion molecule (L1CAM) as a strong prognostic marker in endometrial cancer. To further underline the clinical usefulness of this biomarker, we investigated L1CAM as a ...
    • GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis 

      Cabral-Marques, Otavio; Marques, Alexandre; Melvær, Giil Lasse; De Vito, Roberta; Rademacher, Judith; Günther, Jeannine; Lange, Tanja; Humrich, Jens; Klapa, Sebastian; Schinke, Susanne; Schimke, Lena; Marschner, Gabriele; Pitann, Silke; Adler, Sabine; Dechend, Ralf; Muller, Dominik N.; Braicu, Ioana; Sehouli, Jalid; Schulze-Forster, Kai; Trippel, Tobias; Scheibenbogen, Carmen; Staff, Anne Cathrine; Mertens, Peter; Löbel, Madlen; Mastroianni, Justin; Plattfaut, Corinna; Gieseler, Frank; Dragun, Duska; Engelhardt, Barbara Elizabeth; Fernandez-Cabezudo, Maria; Ochs, Hans D; Al-Ramadi, Basel K; Lamprecht, Peter; Mueller, Antje; Heidecke, Harald; Riemekasten, Gabriela (Peer reviewed; Journal article, 2018-12-06)
      Autoantibodies have been associated with autoimmune diseases. However, studies have identified autoantibodies in healthy donors (HD) who do not develop autoimmune disorders. Here we provide evidence of a network of ...
    • Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial 

      Trovik, Jone; Wik, Elisabeth; Werner, Henrica Maria Johanna; Krakstad, Camilla; Helland, Harald; Vandenput, Ingrid; Njølstad, Tormund Salvesen; Stefansson, Ingunn; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Amant, Frédéric; Akslen, Lars A.; Salvesen, Helga Birgitte (Peer reviewed; Journal article, 2013-11)
      Background: Preoperative histologic examination of tumour tissue is essential when deciding if endometrial cancer surgery should include lymph node sampling. We wanted to investigate if biomarkers could improve prediction ...
    • Late-week surgical treatment of endometrial cancer is associated with worse long-term outcome: Results from a prospective, multicenter study 

      Njølstad, Tormund Salvesen; Werner, Henrica Maria Johanna; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Oddenes, Klaus; Bjørge, Line; Engh, Marie Ellström; Woie, Kathrine; Tjugum, Jostein; Lode, Margaret Sævik; Amant, Frédéric; Salvesen, Helga; Trovik, Jone (Peer reviewed; Journal article, 2017-08-03)
      Surgery is the cornerstone in primary endometrial cancer treatment, and with curative intent it constitutes total hysterectomy and bilateral salpingo-oopherectomy. In addition, lymphadenectomy is performed in selected ...
    • Pregnancy-Related Risk Factors Are Associated With a Significant Burden of Treated Hypertension Within 10 Years of Delivery: Findings From a Population-Based Norwegian Cohort 

      Egeland, Grace M.; Skurtveit, Svetlana; Staff, Anne Cathrine; Eide, Geir Egil; Daltveit, Anne Kjersti; Klungsøyr, Kari; Trogstad, Lill; Magnus, Per; Brantsæter, Anne Lise; Haugen, Margaretha (Peer reviewed; Journal article, 2018-05)
      Background: The association between pregnancy complications and women's later cardiovascular disease has, primarily, been evaluated in studies lacking information on important covariates. This report evaluates the prospective ...