Browsing Bergen Open Research Archive by Author "Stansberg, Christine"
Now showing items 1-9 of 9
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Demonstrating public value to funders and other stakeholders—the journey of ELIXIR, a virtual and distributed research infrastructure for life science data
Martin, Corinne S.; Repo, Susanna; Márquez, Juan Arenas; Blomberg, Niklas; Lauer, Katharina B.; Sitjà, Xènia Pérez; Velek, Premysl; Melo, Ana M. P.; Stansberg, Christine; de Leo, Francesca; Griniece, Elina; Rothe, Hannes; Petryszak, Robert; Smith, Andrew (Journal article; Peer reviewed, 2021)Open Science is a founding principle of ELIXIR, a pan-European research infrastructure for life science data, with 21 Member countries plus the European Molecular Biology Laboratory. The mission of ELIXIR is to coordinate ... -
Gene expression in the rat brain: High similarity but unique differences between frontomedial-, temporal- and occipital cortex
Stansberg, Christine; Ersland, Kari Merete; Valk, Paul van der; Steen, Vidar Martin (Peer reviewed; Journal article, 2011-01-26)Background: The six-layered neocortex of the mammalian brain may appear largely homologous, but is in reality a modular structure of anatomically and functionally distinct areas. However, global gene expression seems to ... -
Gene expression profiles in rat brain disclose CNS signature genes and regional patterns of functional specialisation
Stansberg, Christine; Vik-Mo, Audun O.; Holdhus, Rita; Breilid, Harald; Srebro, Boleslaw; Petersen, Kjell; Jørgensen, Hugo A.; Jonassen, Inge; Steen, Vidar Martin (Peer reviewed; Journal article, 2007-04-04)Background: The mammalian brain is divided into distinct regions with structural and neurophysiological differences. As a result, gene expression is likely to vary between regions in relation to their cellular composition ... -
Gene-Based Analysis of Regionally Enriched Cortical Genes in GWAS Data Sets of Cognitive Traits and Psychiatric Disorders
Ersland, Kari Merete; Christoforou, Andrea; Stansberg, Christine; Espeseth, Thomas; Mattheisen, Manuel; Mattingsdal, Morten; Hardarson, Gudmundur A.; Hansen, Thomas; Fernandes, Carla P. D.; Giddaluru, Sudheer; Breuer, René; Strohmaier, Jana; Djurovic, Srdjan; Nöthen, Markus M.; Rietschel, Marcella; Lundervold, Astri Johansen; Werge, Thomas; Cichon, Sven; Andreassen, Ole Andreas; Reinvang, Ivar; Steen, Vidar Martin; Le Hellard, Stephanie (Peer reviewed; Journal article, 2012-02-22)Background: Despite its estimated high heritability, the genetic architecture leading to differences in cognitive performance remains poorly understood. Different cortical regions play important roles in normal cognitive ... -
Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors
Raa, Anette; Stansberg, Christine; Steen, Vidar Martin; Bjerkvig, Rolf; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug (Journal article, 2007-01-30)This study investigated the effects of hyperoxic treatment on growth, angiogenesis, apoptosis, general morphology and gene expression in DMBA-induced rat mammary tumors. Methods: One group of animals was exposed to normobaric ... -
Implication of NOTCH1 Gene in Susceptibility to Anxiety and Depression among Sexual Abuse Victims
Steine, Iris Mulders; Zayats, Tetyana; Stansberg, Christine; Pallesen, Ståle; Mrdalj, Jelena; Håvik, Bjarte; Soule, Jonathan; Haavik, Jan; Milde, Anne Marita; Skrede, Silje; Murison, Robert; Krystal, John H; Grønli, Janne (Peer reviewed; Journal article, 2016-12-13)Sexual abuse contributes to the development of multiple forms of psychopathology, including anxiety and depression, but the extent to which genetics contributes to these disorders among sexual abuse victims remains unclear. ... -
LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortex
Ersland, Kari Merete; Håvik, Bjarte; Rinholm, Johanne Egge; Gundersen, Vidar; Stansberg, Christine; Steen, Vidar Martin (Peer reviewed; Journal article, 2013-07-11)Background: The neocortex is a highly specialised and complex brain structure, involved in numerous tasks, ranging from processing and interpretation of somatosensory information, to control of motor functions. The normal ... -
Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
Torsvik, Anja; Brattbakk, Hans-Richard; Trentani, Andrea; Holdhus, Rita; Stansberg, Christine; Bartz-Johannessen, Christoffer; Hughes, Timothy; Steen, Nils Eiel; Melle, Ingrid; Djurovic, Srdjan; Andreassen, Ole; Steen, Vidar Martin (Journal article; Peer reviewed, 2023)Schizophrenia (SCZ) and bipolar disorder (BD) share clinical characteristics, genetic susceptibility, and immune alterations. We aimed to identify differential transcriptional patterns in peripheral blood cells of patients ... -
Switch from stress response to homeobox transcription factors in Adipose tissue after profound fat loss
Dankel, Simon N; Fadnes, Dag J.; Stavrum, Anne-Kristin; Stansberg, Christine; Holdhus, Rita; Hoang, Tuyen Thi Van; Veum, Vivian L.; Christensen, Bjørn Jostein; Våge, Villy; Sagen, Jørn V.; Steen, Vidar Martin; Mellgren, Gunnar (Peer reviewed; Journal article, 2010-06-09)Background In obesity, impaired adipose tissue function may promote secondary disease through ectopic lipid accumulation and excess release of adipokines, resulting in systemic low-grade inflammation, insulin resistance ...